Rabeprazole+cinitapride
About Rabeprazole+cinitapride
Rabeprazole+cinitapride belongs to a class of drugs called gastrointestinal agents used to treat gastroesophageal reflux disease (GERD), peptic ulcers and Zollinger-Ellison syndrome. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). Peptic ulcers are sores that develop on the inner lining of the intestine and stomach. Zollinger-Ellison syndrome is characterised by the formation of tumours in the upper part of the small intestine, which leads to excess acid production.
Rabeprazole+cinitapride is a combination of two drugs: Rabeprazole (proton pump inhibitor) and Cinitapride (gastroprokinetic agent). Rabeprazole works by blocking the action of proton pumps that are involved in producing stomach acid. Thereby, it reduces the amount of acid produced by the stomach and prevents excess acid from flowing back into the food pipe. On the other hand, Cinitapride increases the food pipe movement (oesophagus), small intestine and stomach, thereby enhancing bowel movement and the digestive tract gets emptied from the food in a shorter time. Together, Rabeprazole+cinitapride helps in preventing acid reflux, thereby provides relief from hyperacidity and heartburn.
Take Rabeprazole+cinitapride as prescribed by your doctor. You are advised to take Rabeprazole+cinitapride for as long as your doctor has prescribed it for you based on your medical condition. You may experience diarrhoea, nausea, vomiting, headache, dizziness, flatulence (gas), stomach pain, or constipation in some cases. Most of these side effects of Rabeprazole+cinitapride do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Rabeprazole+cinitapride or any other medicines, please tell your doctor. Rabeprazole+cinitapride is not recommended for children as safety and effectiveness were not established. Avoid taking Rabeprazole+cinitapride if you are pregnant, especially in the first 3 months of pregnancy as it may cause harm to the fetus. Therefore, if you are pregnant or breastfeeding, please inform your doctor before taking Rabeprazole+cinitapride. Inform your doctor if you have any risk factors for reduced vitamin B12 as Rabeprazole+cinitapride may reduce the absorption of vitamin B12. Drive only if you are alert as Rabeprazole+cinitapride may cause drowsiness. Avoid alcohol consumption as it may lead to increased stomach acid production, thereby increasing acidity and heartburn.
Uses of Rabeprazole+cinitapride
Medicinal Benefits
Rabeprazole+cinitapride is a combination of two drugs, namely: Rabeprazole and Cinitapride used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. Rabeprazole blocks the action of proton pumps that are involved in producing stomach acid. Thereby, it reduces the amount of acid produced by the stomach and prevents excess acid from flowing back into the food pipe. On the other hand, Cinitapride increases the food pipe movement (esophagus), small intestine, and stomach, thereby enhancing bowel movement and the digestive tract gets emptied from the food in a shorter time. Together, Rabeprazole+cinitapride helps in preventing acid reflux, thereby providing relief from hyperacidity and heartburn.
Directions for Use
Storage
Side Effects of Rabeprazole+cinitapride
- Diarrhoea
- Nausea
- Vomiting
- Headache
- Dizziness
- Flatulence (gas)
- Stomach pain
- Constipation
Patients Concern
Disease/Condition Glossary
Gastroesophageal reflux disease (GERD): The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets irritated or eroded, which leads to complications like GERD, hyperacidity, peptic ulcers, and heartburn. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (esophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, a sour or bitter taste in the mouth, and difficulty swallowing.
Peptic ulcers: These are sores that develop on the stomach and intestine lining due to erosion of the stomach's protective lining. Symptoms include nausea, appetite changes, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.
Zollinger-Ellison syndrome: It is characterized by the formation of tumors in the upper part of the small intestine, which leads to excess acid production. Symptoms include bloating, burping, weight loss, loss of appetite, nausea, and vomiting.
FAQs
Rabeprazole+cinitapride contains Rabeprazole and Cinitapride. Rabeprazole works by blocking the action of proton pumps that are involved in producing stomach acid. Thereby, it reduces the amount of acid produced by the stomach and prevents excess acid flowing back into the food pipe. On the other hand, Cinitapride increases the movement of the food pipe (oesophagus), small intestine and stomach, thereby enhancing bowel movement and digestive tract gets emptied from the food in a shorter time. Together, Rabeprazole+cinitapride helps in preventing acid reflux, thereby provides relief from hyperacidity and heartburn.
Rabeprazole+cinitapride may cause diarrhoea as a common side effect. However, if the condition persists or worsens with fever, watery or bloody stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while taking Rabeprazole+cinitapride to prevent dehydration.
Rabeprazole+cinitapride may cause low levels of magnesium in the blood if taken for more than 3 months. If you experience involuntary muscle contractions, fits, tiredness, increased heart rate or dizziness while taking Rabeprazole+cinitapride, please consult a doctor immediately as these might be signs of low magnesium levels. However, regular blood tests are recommended to monitor magnesium levels in the blood while taking Rabeprazole+cinitapride.
You are not recommended to take Rabeprazole+cinitapride with antifungals such as ketoconazole or itraconazole as it may reduce the effectiveness of antifungal against fungal infections. However, please consult your doctor before taking Rabeprazole+cinitapride with other medicines.
Rabeprazole+cinitapride may reduce the absorption of vitamin B12 and lead to its deficiency if used for more than 3 years. Therefore, inform your doctor if you have any risk factors for reduced vitamin B12 before taking Rabeprazole+cinitapride.
Rabeprazole+cinitapride should be used with caution in osteoporosis (weak and brittle bones) patients as it may worsen the condition especially if Rabeprazole+cinitapride is taken for more than 1 year as it increases the risk of fracture of the spine, hip or wrist. Therefore, inform your doctor if you have osteoporosis or take any steroids which may increase the risk of osteoporosis.
Rabeprazole+cinitapride may cause tardive dyskinesia (involuntary and abnormal movements) in elderly patients if taken for a prolonged time. Therefore, it is recommended to use Rabeprazole+cinitapride only for the duration as prescribed by a doctor.
