Pregabalin+nortriptyline
About Pregabalin+nortriptyline
Pregabalin+nortriptyline is a combination medicine indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. Neuropathic pain is a chronic progressive nerve disease which causes nerve pain due to nerve damage or a malfunctioning nervous system.
Pregabalin+nortriptyline is a combination of two drugs: Pregabalin (anti-convulsant) and Nortriptyline (antidepressant). Pregabalin affects the chemicals in the brain that send pain signals across the nervous system. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Together, Pregabalin+nortriptyline helps to treat neuropathic pain.
In some cases, you may experience certain common side-effects such as dizziness, sleepiness, nausea, blurred vision, peripheral oedema (swelling of lower legs and hands), weight gain and dry mouth. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
Consult your doctor if you are pregnant or breastfeeding. Pregabalin+nortriptyline may cause drowsiness and dizziness, so drive only if you are alert. Pregabalin+nortriptyline should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Pregabalin+nortriptyline as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.
Uses of Pregabalin+nortriptyline
Medicinal Benefits
Pregabalin+nortriptyline is a combination of two medicines, namely: Pregabalin and Nortriptyline. Pregabalin+nortriptyline is indicated for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, spinal cord injury, etc. Pregabalin is an anti-convulsant which affects the chemicals in the brain that send pain signals across the nervous system. Nortriptyline is an antidepressant which works by increasing the levels of nerve transmitters (serotonin and noradrenaline) in the brain, thereby reduces the pain messages arriving in the brain. Together, Pregabalin+nortriptyline helps to treat neuropathic pain (pain due to nerve damage).
Directions for Use
Storage
Side Effects of Pregabalin+nortriptyline
- Dizziness
- Sleepiness
- Nausea
- Blurred vision
- Peripheral oedema (swelling of lower legs and hands)
- Weight gain
- Dry mouth
Patients Concern
Disease/Condition Glossary
Neuropathic pain: Neuropathic pain is caused due to damaged sensory nerves. It is caused by chronic progressive nerve disease, infection or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping and evoked pain (pain caused by events usually not painful).
FAQs
Pregabalin+nortriptyline contains Pregabalin and Nortriptyline. Pregabalin affects the chemicals in the brain that send pain signals across the nervous system. Nortriptyline works by increasing nerve transmitters (serotonin and noradrenaline) in the brain, thereby reducing the pain messages arriving in the brain. Together, Pregabalin+nortriptyline helps to treat neuropathic pain.
Pregabalin+nortriptyline may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.
Dry mouth could be a side-effect of Pregabalin+nortriptyline. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
To treat your condition effectually, continue taking Pregabalin+nortriptyline for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Pregabalin+nortriptyline.
Pregabalin+nortriptyline is used to treat nerve pain due to diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in the legs and feet.
Pregabalin+nortriptyline may cause peripheral oedema. Peripheral oedema is the swelling of hands and lower legs. Avoid sitting or standing for too long. Raise your legs by putting a pillow under the legs while lying down.
