Pregabalin+amitriptyline
About Pregabalin+amitriptyline
Pregabalin+amitriptyline is a combination medicine indicated for the management of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease which causes nerve pain due to nerve damage or a malfunctioning nervous system. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation.
Pregabalin+amitriptyline is a combination of two drugs: Pregabalin (anti-convulsant), and Amitriptyline (antidepressant). Pregabalin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Amitriptyline increases the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Together, Pregabalin+amitriptyline helps to treat neuropathic pain.
You are advised to take Pregabalin+amitriptyline for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as weight gain, dry mouth, blurred vision, dizziness, tiredness, nausea, vomiting, diarrhoea, and constipation. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
Consult your doctor if you are pregnant or breastfeeding. Pregabalin+amitriptyline may cause drowsiness and dizziness, so drive only if you are alert. Pregabalin+amitriptyline should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Pregabalin+amitriptyline as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.
Uses of Pregabalin+amitriptyline
Medicinal Benefits
Pregabalin+amitriptyline is a combination of two drugs: Pregabalin (anti-convulsant), and Amitriptyline (antidepressant). Pregabalin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Amitriptyline increases the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Together, Pregabalin+amitriptyline helps to treat neuropathic pain.
Directions for Use
Storage
Side Effects of Pregabalin+amitriptyline
- Weight gain
- Dry mouth
- Blurred vision
- Dizziness
- Tiredness
- Nausea
- Vomiting
- Diarrhoea
- Constipation
Patients Concern
Disease/Condition Glossary
Neuropathic pain: Neuropathic pain is caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events usually not painful).
FAQs
Pregabalin+amitriptyline contains Pregabalin and Amitriptyline. Pregabalin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Amitriptyline increases the level of serotonin and noradrenaline, thereby decreasing the movement of pain receptors. Together, Pregabalin+amitriptyline helps to treat neuropathic pain.
Pregabalin+amitriptyline may cause weight gain due to an increase in appetite. Maintain a healthy weight by regular exercise and following a proper diet.
Dry mouth could be a side-effect of Pregabalin+amitriptyline. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
To treat your condition effectually, continue taking Pregabalin+amitriptyline for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Pregabalin+amitriptyline; your doctor will reduce the dose gradually.
Pregabalin+amitriptyline is used to treat neuropathic pain due to diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in legs and feet.
Pregabalin+amitriptyline may cause sexual disturbances such as decreased sex drive and problems with erection. Consult your doctor if you have any concerns regarding this.
