PETHIDINE
About
PETHIDINE belongs to a class of drugs called opioid analgesics (pain killers). PETHIDINE is used to relieve moderate to severe pain and pain relief during labour. It may also stop you from feeling pain before and during an operation and provide continuous pain relief if needed. Pain is an unpleasant sensation caused by an injury or illness. Pain may be acute or chronic. It can be general (overall body pains) or localized (pain in a specific body area).
PETHIDINE contains Pethidine. It works to reduce feelings of pain by interrupting the way nerves signal pain between the brain and the body.
A qualified healthcare professional will administer PETHIDINE. Sometimes, you may experience restlessness, drowsiness, constipation, dry mouth, nausea, vomiting, facial flushing, sweating, a fast or slow heartbeat, palpitations (an irregular heart rhythm or missed beats), low blood pressure, mood changes, pain, redness or itching at the injection site, dizziness, dizziness, and muscle twitching. Most of these side effects of PETHIDINE do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.
Inform your doctor if you are allergic to any of the components in this medicine. Also, please inform your doctor about your health condition and medications before taking PETHIDINE to rule out any side effects. Inform your doctor If you are pregnant, suspect pregnancy, plan to have a baby, or are a nursing mother. Your doctor will discuss the possible risks and benefits of taking Pethidine during pregnancy. Consumption of alcohol should be avoided during therapy. You must not drive or operate machinery while receiving PETHIDINE.
Uses of PETHIDINE
Medicinal Benefits
PETHIDINE contains Pethidine, which belongs to the opioid analgesics (pain relievers) class of medicines. Pethidine Injection is used to relieve moderate to severe pain and is also used to relieve pain during labour. It may also be used to prevent discomfort before and during surgery, as well as to offer continuous pain relief if necessary. Pethidine helps alleviate pain by interfering with how nerves communicate pain between the brain and the body.
Directions for Use
Side Effects of PETHIDINE
- Restlessness
- Constipation
- Dry mouth
- Nausea
- Vomiting
- Facial flushing
- Sweating
- A fast or slow heartbeat
- Palpitations
- Low blood pressure
- Feeling dizzy or light-headed
- Feeling weak and fainting
- High blood pressure
- A feeling of dizziness or spinning
- Fainting
- Feeling weak
- Hallucinations
- Mood changes
- Headache
- Slowed breathing
- A red, itchy rash
- Reduced sex drive
- Pain, redness or itching at the injection site
- A feeling of intense happiness
- Difficulty in passing urine
- Addiction
- Confusion
- Tremor or involuntary shaking
- Dry eye
- Dizziness or drowsiness
- Muscle twitching
In-Depth Precautions and Warning
Drug Warnings
Pethidine tablets should not be given to you if you are an asthmatic, have breathing problems or have severe disease relating to the lungs, suffering from a head injury or brain tumour, or have an irregular heartbeat (arrhythmia), or are undergoing treatment with, or have finished treatment in the last two weeks with, monoamine oxidase (MAO) inhibitors (e.g. phenelzine, tranylcypromine, moclobemide), have severe liver or kidney disease, have blood-thinning problems, or are receiving treatment for this disorder (e.g. warfarin), have alcohol use disorder, have a blockage in the stomach and intestine (severe constipation) or have severe pain in the stomach with bloating, gut cramps and vomiting (paralytic ileus). So, before taking the PETHIDINE, let your doctor know about all your medical conditions, sensitivities, and all medications you are using.
Drug Interactions
Drug-Drug Interactions: PETHIDINE may have interaction with sedative-hypnotics (e.g. zolpidem), benzodiazepines (e.g. lorazepam, alprazolam), anti-depression medications (e.g. duloxetine, fluoxetine), skeletal muscle relaxants (e.g. cyclobenzaprine), anticonvulsants (e.g. gabapentin) and monoamine oxidase inhibitors (e.g. phenelzine, tranylcypromine, moclobemide) and blood thinners (warfarin).
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: PETHIDINE may interact with various disease conditions, including asthma, breathing problems, diabetes, phaeochromocytoma (a tumour of the adrenal gland), convulsive disorder (fits), head injury or brain tumour, irregular heartbeat (arrhythmia), severe liver or kidney disease, alcohol use disorder, blockage in the stomach and intestine (severe constipation), severe pain in the abdomen with bloating, gut cramps, and vomiting (paralytic ileus).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAvoid alcohol consumption while on treatment with PETHIDINE.
Pregnancy
cautionPETHIDINE is used for pain relief during labour. However, caution is advised as PETHIDINE may cause respiratory depression in newborns.
Breast Feeding
cautionPethidine can pass into your baby through your breast milk. This may cause respiratory problems in babies. So, your doctor may suggest stopping breastfeeding for a certain time after treatment per the doctor's direction.
Driving
cautionPETHIDINE may affect your reactions and your ability to drive. Do not drive and/or operate machines that require your alertness.
Liver
cautionPETHIDINE is not recommended to be used in patients with severe liver impairment. The dose of this medicine may have to be reduced in case of mild to moderate liver disease.
Kidney
cautionPETHIDINE is not recommended to be used in patients with severe kidney impairment. The dose of this medicine may have to be reduced in case of mild to moderate kidney disease.
Children
safe if suggestedIt can be used to relieve moderate to severe acute pain in children.
Habit Forming
Diet & Lifestyle Advise
- Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
- Performing yoga may also help in improving joint flexibility and pain management.
- Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
- Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.
- Follow heat or cold therapy, and apply a cold or hot compress on the joints for 15-20 minutes regularly.
- De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
- Acupuncture, massage and physical therapy may also be helpful.
- Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
- Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
- Avoid smoking and alcohol consumption.
Patients Concern
Disease/Condition Glossary
Pain: Pain is an unpleasant emotion brought on by an illness or injury. Acute or chronic pain both exist. Since different people have varying pain tolerance levels, pain is highly subjective. Even though pain is uncomfortable and inconvenient, it can provide clues as to what is wrong with the body. Cramps, headaches, bone fractures, stomach pain, arthritis (swelling of one or more joints), muscle strain or overuse, cuts, the flu, fibromyalgia, and irritable bowel syndrome are a few conditions that can cause pain (muscle pain with stiffness and tenderness).
FAQs
PETHIDINE contains Pethidine. It alleviates pain by interfering with how nerves communicate pain between the brain and the body.1
PETHIDINE may cause nausea and vomiting. It is not necessary for everyone taking PETHIDINE to experience these side effects. However, if the condition persists or worsens, consult your doctor.2
PETHIDINE is not recommended for people with supraventricular tachycardia. Inform your doctor if you are suffering from supraventricular tachycardia.3
PETHIDINE can be used in elderly or disabled patients. However, the initial dose should not exceed 25mg because this group of individuals may be especially sensitive to the drug's central depressive consequences.4