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Ofloxacin+tinidazole

About Ofloxacin+tinidazole

Ofloxacin+tinidazole is a combination of medicine called 'antibiotics' primarily used to treat various infections caused by bacteria & protozoans. Ofloxacin+tinidazole is used to treat a wide variety of infections caused by susceptible Gram-positive organisms, Gram-negative organisms, anaerobes, and protozoa. Examples of infection caused by protozoa include dysentery (inflammation of the colon) and malaria. 

Ofloxacin+tinidazole is a combination of two antibiotics: Ofloxacin and Tinidazole. Ofloxacin helps in treating and preventing a wide range of bacterial infections. It is bactericidal in nature, which means it works by killing bacteria that cause infections. It inhibits bacterial cells' process, ultimately destroying the bacteria, thereby preventing the further spread of the infection. Ofloxacin+tinidazole is a broad-spectrum antibiotic against most Gram-negative bacteria, many Gram-positive bacteria, and some anaerobes bacteria (that live without oxygen). On the other hand, Tinidazole kills parasites and anaerobic bacteria responsible for causing infections. It works by damaging their genetic material called DNA. 

Ofloxacin+tinidazole should be taken in the dose and duration your doctor advises. It is recommended to take it with food and be taken at a fixed time to achieve maximum effect. You may sometimes experience nausea, vomiting, stomach pain, loss of appetite, headache, etc. Most of these side effects of Ofloxacin+tinidazole do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Please consult your doctor immediately if you experience any allergic reaction symptoms such as rashes, itching, swelling, or shortness of breath.

Inform your doctor if you have any lung disease, muscle weakness (myasthenia gravis), sleeping disorder or difficulty sleeping (sleep apnoea), severe liver disease, or problem with alcohol or other prescription recreational drugs. Inform your doctor if you plan to get pregnant, are pregnant, or are breastfeeding. Use of Ofloxacin+tinidazole is associated with an increased risk of tendinitis and tendon (tough tissue that connects muscle to bone) rupture in all ages. People taking Ofloxacin+tinidazole who are over 60 years are at high risk, especially those taking anti-allergic medicines like corticosteroid drugs. Ofloxacin+tinidazole is contraindicated in people with kidney/heart diseases and those who have had lung transplants, should its use is not recommended.

Uses of Ofloxacin+tinidazole

Bacterial infections, Protozoal infections

Medicinal Benefits

Ofloxacin+tinidazole contains antibiotic Ofloxacin and Tinidazole, which helps treat and prevent a wide range of bacterial infections caused by Gram-negative bacteria, Gram-positive bacteria and some anaerobic bacteria (that live without oxygen). It is bactericidal and works by killing bacteria that cause infections by preventing the formation of their cell wall required for living. It also inhibits the repairing of bacterial cells. Altogether it kills the bacteria. Ofloxacin+tinidazole has the advantage of good penetration in most deep tissues and body fluids. Hence, it is also suitable for the treatment of deep tissue and bone bacterial infections. 

Directions for Use

This medicine can be taken with or without food (excluding dairy products). Ofloxacin+tinidazole should not be used unless prescribed by a doctor. Always take this medicine exactly as your doctor has told you. Check with your doctor if you are not sure. Tablet: Swallow the tablet with water; Do not chew or crush the medicine. Suspension: Shake the bottle well before each use. Take/administer the prescribed dose using the measuring cup/dosing syringe/dropper.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ofloxacin+tinidazole

  • Nausea
  • Vomiting
  • Headache
  • Headache
  • Metallic taste 
  • Stomach pain
  • Loss of appetite
  • Dryness in the mouth

Patients Concern

Disease/Condition Glossary

A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our bodies. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms comprising, commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. A few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. People with weak immune systems or taking immunosuppressive medicine can make them more prone to bacterial infection.

Pneumonia: In this type of infection, there is inflammation of the air sacs in one or both lungs. It can be caused by various organisms, including bacteria, viruses, and fungi.

Endocarditis: It is the infection of the inner lining of heart chambers and heart valves. It can occur when micro-organisms such as bacteria, fungi or other germs from other body parts, such as the mouth, spread through the bloodstream and get attached to damaged areas in the heart.

Septic arthritis: It is also known as joint infection or infectious arthritis. Joint inflammation is due to an infectious agent's invasion of a joint.

Osteomyelitis: It is an infection of the bone caused by staphylococcus bacteria that can be found in the nose or skin in healthy individuals.

Meningitis: It is inflammation of the meninges in which the membranes covering the brain and spinal cord get inflamed. It occurs due to infection, which bacteria or viruses can cause.

Dysentery: It is inflammation of the intestine, particularly the colon, caused by the bacteria Shigella.

Diarrhoea: It is a medical condition in which a person faces loose, watery stools loose or a frequent need to have a bowel movement.

FAQs

Not recommended. A patient with a transplanted kidney might be taking an immunosuppressive drug like cyclosporin which is contraindicated with Ofloxacin+tinidazole failing the efficacy of the Immnosuppresant drug. There are chances of rejection of the transplanted kidney in the patient and, hence, not recommended to take Ofloxacin+tinidazole without a doctor's consultation.

Do not consume alcohol or alcohol-based products while taking Ofloxacin+tinidazole and at least 3 days after your treatment commences. You may experience unpleasant side effects such as fast heartbeats, nausea, vomiting, sweating and tingling under your skin.

Yes, after taking Ofloxacin+tinidazole, you may have diarrhoea. Ofloxacin+tinidazole is an antibiotic that kills or prevents bacterial growth, so some good intestinal bacteria that aid digestion might also get killed. So, drink plenty of fluids and take probiotics to prevent excessive loss of fluids from the body (dehydration).

It is advised not to take Ofloxacin+tinidazole should not be taken along with dairy products as it might affect the absorption and efficacy of Ofloxacin+tinidazole. However, you can take it with a meal that includes these foods or drinks.

Ofloxacin+tinidazole makes your skin sensitive to sunlight, known as photosensitivity. So, prolonged exposure to sunlight or ultraviolet light should be avoided. In case of emergency, you should always wear sunscreen before going out.

If you miss a dose of Ofloxacin+tinidazole, take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.

Take Ofloxacin+tinidazole either 2 hours before or 2 hours after taking an antacid, multivitamin, or other product that has calcium/magnesium/aluminium/iron/zinc, antiulcer agent (sucralfate) or anti-HIV drug (didanosine).

No, Ofloxacin+tinidazole should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects. If you think your symptoms are not improving, please consult your doctor

Ofloxacin+tinidazole contains lactose so tell your doctor if you are intolerant to some sugars.

It is advised to tell your doctor if you are already taking Warfarin before taking Ofloxacin+tinidazole as it can increase the time it takes for blood clotting.

Available Medicines for

Ofloxacin+tinidazole

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