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NIMESULIDE+CHLORZOXAZONE

About NIMESULIDE+CHLORZOXAZONE

NIMESULIDE+CHLORZOXAZONE belongs to the group of medicines called muscle relaxants indicated for the relief of painful skeletal muscle spasms. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasms are the involuntary contractions of muscles which can be painful. Musculoskeletal pain affects the bones, muscles, ligaments, tendons and nerves.

NIMESULIDE+CHLORZOXAZONE is a combination of two drugs: Nimesulide (NSAID) and Chlorzoxazone (Muscle relaxant). Nimesulide works by inhibiting the synthesis of prostaglandins which are responsible for pain and inflammation. Chlorzoxazone acts on the brain and spinal cord centres where it inhibits multisynaptic reflex involved in muscle spasms, thereby providing relief from skeletal muscle spasms or stiffness. Together, NIMESULIDE+CHLORZOXAZONE helps in relieving musculoskeletal pain.

You are advised to take NIMESULIDE+CHLORZOXAZONE for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, NIMESULIDE+CHLORZOXAZONE may cause common side-effects such as nausea, vomiting, diarrhoea, weakness, and stomach upset. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. NIMESULIDE+CHLORZOXAZONE is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with NIMESULIDE+CHLORZOXAZONE as it could increase the risk of stomach bleeding. NIMESULIDE+CHLORZOXAZONE may cause sleepiness and dizziness, so drive only if you are alert. Keep your doctor informed about your health condition and medicines to rule out any side-effects/interactions.

Uses of NIMESULIDE+CHLORZOXAZONE

Musculoskeletal pain

Medicinal Benefits

NIMESULIDE+CHLORZOXAZONE is a combination of two drugs, namely: Nimesulide and Chlorzoxazone. NIMESULIDE+CHLORZOXAZONE is used to relieve pain and stiffness caused by muscle strains and sprains. Nimesulide is an NSAID that inhibits the synthesis of prostaglandins responsible for pain and inflammation. Chlorzoxazone is a muscle relaxant that acts on the brain and spinal cord centres, where it inhibits the multisynaptic reflex involved in muscle spasms, thereby providing relief from skeletal muscle spasms or stiffness. Together, NIMESULIDE+CHLORZOXAZONE helps in relieving pain due to muscle spasms.

Directions for Use

Take NIMESULIDE+CHLORZOXAZONE with food to prevent stomach upset. Swallow NIMESULIDE+CHLORZOXAZONE as a whole with a glass of water, do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of NIMESULIDE+CHLORZOXAZONE

  • Nausea
  • Vomiting
  • Diarrhoea
  • Weakness
  • Stomach upset
  • Heart burn or abdominal cramps

Patients Concern

Disease/Condition Glossary

Musculoskeletal pain: Musculoskeletal pain affects the bones, muscles, ligaments, tendons and nerves. It can be acute or chronic and can be localised or widespread. The pain can be mild or severe enough to interfere with your daily routine. Musculoskeletal pain could occur due to arthritis, osteoporosis, fractures, dislocations, problems with the bone structure or injury to the bones, joints, tendons, muscles and ligaments. Symptoms of musculoskeletal pain include stiffness, swelling, redness, weakness, muscle spasms or twitching, trouble moving the affected area, soreness, and cracking or popping sound at the joints.

FAQs

NIMESULIDE+CHLORZOXAZONE contains Nimesulide and Chlorzoxazone. Nimesulide works by inhibiting the synthesis of prostaglandins responsible for pain and inflammation. Chlorzoxazone acts on the brain and spinal cord centres, where it inhibits the multisynaptic reflex involved in muscle spasms, thereby providing relief from skeletal muscle spasms. Together, NIMESULIDE+CHLORZOXAZONE helps in relieving musculoskeletal pain.

NIMESULIDE+CHLORZOXAZONE is generally prescribed for short-term use. Avoid taking NIMESULIDE+CHLORZOXAZONE for longer durations unless prescribed by the doctor, as it could lead to unpleasant side effects and liver damage. Use the minimum effective dose for the shortest duration of time.

Do not take NIMESULIDE+CHLORZOXAZONE along with other painkiller medicines unless prescribed by the doctor, as it can lead to unpleasant side effects and can increase the risk of stomach bleeding associated with NSAIDs.

Physical therapy helps relieve muscle spasms. Therefore, proper rest and physical therapy are recommended to enhance and complement treatment with NIMESULIDE+CHLORZOXAZONE.

Diarrhoea might be a side-effect of NIMESULIDE+CHLORZOXAZONE. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in stools.

NIMESULIDE+CHLORZOXAZONE contains Nimesulide, an NSAID, which can enhance the activity of anticoagulant drugs leading to an increased risk of bleeding complications. Therefore, it is not recommended to take anti-coagulants along with NIMESULIDE+CHLORZOXAZONE unless told by the doctor.

Available Medicines for

NIMESULIDE+CHLORZOXAZONE

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