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MOXIFLOXACIN+LOTEPREDNOL

About MOXIFLOXACIN+LOTEPREDNOL

MOXIFLOXACIN+LOTEPREDNOL belongs to a group of medications called 'Antibiotics and Corticosteroids' used to treat bacterial eye infections or eye discomfort. It is also used in patients who have undergone eye surgeries. It is effectively used to treat eye inflammation caused by allergies, shingles, severe acne, iritis (inflammation of the coloured part of the eye (iris)), uveitis (inflammation of the middle layer of the eye (uvea)), eye injury, radiation, and chemical burns. A bacterial eye infection occurs when bacteria invade any part of the eyeball or its surrounding tissues, including the cornea (clear front surface of the eye) and the conjunctiva (thin membrane lining the outer eye and inner eyelids). MOXIFLOXACIN+LOTEPREDNOL is used to prevent or treat only bacterial eye infections. It does not work against infections caused by viruses and fungi.

MOXIFLOXACIN+LOTEPREDNOL contains two medicines: Moxifloxacin (antibiotic) and Loteprednol (corticosteroid). Moxifloxacin belongs to a class of drugs called fluoroquinolone antibiotics. Moxifloxacin is an antibiotic that helps treat and prevent a wide range of bacterial infections. It kills bacteria (bactericidal action) by preventing the synthesis of enzymes, namely DNA gyrase and Topoisomerase II and IV, which is essential for the growth and survival of the bacterial cell. Loteprednol belongs to the class of corticosteroids. It blocks prostaglandins' production (chemical messengers), making the eye red, swollen, and itchy. Together, MOXIFLOXACIN+LOTEPREDNOL prevents the spread of eye infections caused by bacteria and reduces inflammation and pain.

MOXIFLOXACIN+LOTEPREDNOL is available in the form of an ophthalmic solution (eye drops). Your doctor will advise on how often you take MOXIFLOXACIN+LOTEPREDNOL based on your medical condition. Some common side effects of eye drop formulation of MOXIFLOXACIN+LOTEPREDNOL include redness in the eyes, blurred vision, burning or stinging sensation in the eye, and eye discomfort. These side effects do not require medical attention and gradually resolve over time.

Please do not use MOXIFLOXACIN+LOTEPREDNOL without consulting your doctor if you have a damaged cornea, ulcers in the eye, eye infection and producing pus, open lesions in the eye, and glaucoma (a condition where the pressure inside the eye is increased). Inform your doctor if you are pregnant or breastfeeding before using MOXIFLOXACIN+LOTEPREDNOL. Avoid touching the eyedropper with bare hands or taking it closer to the eyelids while administering drops since it contaminates the dropper tip and solution. If you wear contact lenses, please inform your doctor since the MOXIFLOXACIN+LOTEPREDNOL may contain additives like Benzalkonium chloride that change the lens's colour. MOXIFLOXACIN+LOTEPREDNOL sometimes may make your eye red after administration; in such cases, please avoid wearing a lens until the eye improves. Avoid driving or operating machines since the administration of eye drops of MOXIFLOXACIN+LOTEPREDNOL cause blurred vision for a while after use.

Uses of MOXIFLOXACIN+LOTEPREDNOL

Bacterial eye infections, allergic eye conditions.

Medicinal Benefits

MOXIFLOXACIN+LOTEPREDNOL is a combination of two medicines: Moxifloxacin and Loteprednol. Moxifloxacin is a fluoroquinolone and broad-spectrum antibiotic. It can act against both gram-positive and gram-negative bacteria. It kills bacteria (bactericidal action) by preventing the synthesis of enzymes, namely DNA gyrase and Topoisomerase II and IV, which is essential for the growth and survival of the bacterial cell. Loteprednol is a corticosteroid with anti-inflammatory properties and acts by inhibiting the chemicals such as prostaglandins production (chemical messengers) that make the eye red, swollen, and itchy. It reduces symptoms associated with infection, such as redness and irritation of the eye, and decreases the risk of infections. Collectively, MOXIFLOXACIN+LOTEPREDNOL treats and prevents bacterial eye infections and eye inflammation caused by allergies, shingles, severe acne, iritis (inflammation of the coloured part of the eye (iris)), uveitis (inflammation of the middle layer of the eye (uvea)), eye injury, radiation, and chemical burns. MOXIFLOXACIN+LOTEPREDNOL is used to prevent or treat only bacterial eye infections. It does not work against infections caused by viruses and fungi.

Directions for Use

MOXIFLOXACIN+LOTEPREDNOL is for ophthalmic use only. Wash your hands thoroughly before and after using MOXIFLOXACIN+LOTEPREDNOL. Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops as advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes. Replace the outer cap after use. Please do not touch the container’s tip to the eye, eyelids or surrounding areas as it may contaminate MOXIFLOXACIN+LOTEPREDNOL.

Storage

Store in a cool and dry place away from sunlight

Side Effects of MOXIFLOXACIN+LOTEPREDNOL

  • Blurred vision
  • Burning/stinging sensation in the eyes
  • Redness in the eyes
  • Watery eyes
  • Inflammation of cornea

Patients Concern

Disease/Condition Glossary

Bacterial eye infections: Bacterial eye infections are the common eye problems seen in a primary care setting. The common eye problems are conjunctivitis (inflammation of the conjunctiva), stye (bump on the eyelid), and keratitis (inflammation of the cornea). The risk for eye infection is high in post-operative patients or patients who have undergone Lasik, cataract, or other eye surgeries.

Conjunctivitis: A condition caused by the inflammation and irritation of the eye's mucous membrane (conjunctiva).

FAQs

MOXIFLOXACIN+LOTEPREDNOL contains Moxifloxacin and Loteprednol. Moxifloxacin is an antibiotic that prevents bacterial cells from dividing and repairing, thereby killing the bacteria. Loteprednol, a corticosteroid, blocks prostaglandins' production (chemical messengers), making the eye red, swollen and itchy. Collectively, MOXIFLOXACIN+LOTEPREDNOL helps relieve and treat symptoms of bacterial eye infections.

You are not recommended to stop using MOXIFLOXACIN+LOTEPREDNOL without consulting your doctor even if you feel better, as it may increase pressure in the eyes and may lead to loss of vision. Your symptoms may improve before the infection is completely cured. Therefore, use MOXIFLOXACIN+LOTEPREDNOL for as long as your doctor has prescribed it, and if you experience any difficulty while taking MOXIFLOXACIN+LOTEPREDNOL, please consult your doctor.

If you are using other eye drops along with MOXIFLOXACIN+LOTEPREDNOL, maintain an interval of at least 10 minutes before administering other medicines in the same eye to avoid dilution.

MOXIFLOXACIN+LOTEPREDNOL is generally prescribed for seven days. You should take this medicine for a duration given by your doctor. Avoid prolonged use, as it may cause cataracts (clouding of the eye) and increase the second infection risk. If you use MOXIFLOXACIN+LOTEPREDNOL for longer than ten days, you may need frequent vision tests to check the pressure inside your eyes.

MOXIFLOXACIN+LOTEPREDNOL can cause blurry vision for some time in the beginning. Avoid driving and operating machinery in such cases until you feel better. If the effect persists longer, seek medical attention.

Avoid prolonged use, as it may cause cataracts (clouding of the eye) and increase the risk of a second infection. Also, do not wear contact lenses while using MOXIFLOXACIN+LOTEPREDNOL.

Available Medicines for

MOXIFLOXACIN+LOTEPREDNOL

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