Voglibose+metformin

Metformin+voglibose belongs to the class of anti-diabetic drugs. It is used in the treatment of type 2 diabetes mellitus. Diabetes mellitus is a metabolic disease that causes high blood sugar levels. It occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance) or the pancreas (an organ behind the stomach) produces little or no insulin at all.

Metformin+voglibose is composed of two medicines, namely Voglibose and Metformin. Voglibose belongs to the class of alpha-glucosidase inhibitors. It acts by inhibiting the intestinal enzymes, which break complex sugars into simple sugars such as glucose. This process prevents the rise of blood glucose levels. Metformin belongs to the class of biguanides and exhibits non-pancreatic effect to reduce serum glucose levels without increasing insulin secretion. It is also known as an insulin sensitizer as it increases the effects of insulin. Metformin is considered to be a unique anti-diabetic drug since it does not cause hypoglycemia (lowered blood sugar levels).

Take Metformin+voglibose with food at regular intervals as prescribed by your doctor. Your doctor will decide the dosage form, and this may change timely depending on your blood sugar levels. The common side effects of Metformin+voglibose include nausea, vomiting, changes in taste, diarrhoea, dizziness, stomach pain, shortness of breath, skin rash, bloating, and flatulence (intestinal wind/gas). Although not everyone experiences these side effects, if they occur, seek medical attention. Lactic acidosis, is a rare, but serious metabolic complication of excess lactic acid in the blood that is caused by metformin accumulation is reported. The risk of lactic acidosis is high in people with kidney, liver, and heart diseases.

Before starting Metformin+voglibose, let your doctor know if you have any medical history of anaemia (low hemoglobin levels), seizures (fits), heart, kidney, and liver diseases. Metformin+voglibose does not cause hypoglycemia (low blood sugar levels). However, when used with other diabetic drugs like insulin or sulfonylureas, it can lead to hypoglycemia. Also, speak to your doctor if you are on restricted food or fluid intake since Metformin+voglibose causes dehydration, low blood sugar, and kidney damage. Do not take Metformin+voglibose if you have gastrointestinal diseases like ulcerative colitis or Crohn’s disease. Do not take or stop Metformin+voglibose, if the doctor did not advise you to do so.

Type 2 Diabetes mellitus.

Metformin+voglibose is used to treat type 2 diabetes mellitus. It is a combination of Voglibose and Metformin. Voglibose belongs to the class of alpha-glucosidase inhibitors. It delays glucose absorption by inhibiting the intestinal enzymes, which break complex sugars into simple sugars such as glucose. This process prevents the rise of blood glucose levels immediately after meals. Metformin belongs to the class of biguanides. It shows the non-pancreatic effect to reduce serum glucose levels without increasing insulin secretion. It is also known as an insulin sensitizer as it increases the effects of insulin. It is considered to be a unique anti-diabetic drug since it does not lower blood sugar levels. Metformin does not cause weight gain in most cases.

Tablet: Swallow it as a whole with water; do not crush, break or chew it. Take Metformin+voglibose preferably with a meal, since it lowers the blood sugar levels and causes gastrointestinal side effects. Your doctor may start the course with a low dose and gradually maintain an effective dose to achieve the required blood glucose control.

Store in a cool and dry place away from sunlight

Common side effects:

• Nausea
• Vomiting
• Changes in taste
• Diarrhoea
• Dizziness
• Stomach pain
• Shortness of breath
• Skin rash
• Bloating
• Flatulence (intestinal wind/gas)

Rare side effects:

• Lactic acidosis