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Loteprednol+tobramycin

About Loteprednol+tobramycin

Loteprednol+tobramycin is an ophthalmic (for eye use) medication, primarily used to treat and prevent bacterial eye infections. It is effectively used to treat eye inflammation caused by allergies, shingles, severe acne, iritis (inflammation of the coloured part of the eye (iris)), uveitis (inflammation of the middle layer of the eye (uvea)), eye injury, radiation, and chemical burns. A bacterial eye infection occurs when bacteria invade any part of the eyeball or its surrounding tissues, including the cornea (clear front surface of the eye) and the conjunctiva (thin membrane lining the outer eye and inner eyelids).

Loteprednol+tobramycin contains two medicines, namely: Tobramycin (antibiotic) and Loteprednol (corticosteroid). Tobramycin belongs to a class of drugs called aminoglycoside antibiotics. It inhibits bacteria growth by interfering with protein synthesis. It binds to the bacteria's proteins, disrupting the cell membrane, and eventually leading to cell death. Loteprednol belongs to the class of corticosteroids. It blocks prostaglandins' production (chemical messengers) that make the eye red, swollen and itchy.

Your doctor will advise on how often you take Loteprednol+tobramycin based on your medical condition. Some common side effects of Loteprednol+tobramycin include blurred vision, burning/stinging sensation in the eye, and eye discomfort. These side effects do not require medical attention and gradually resolve over time.

Please do not use Loteprednol+tobramycin without consulting your doctor if you have any heart, liver and kidney diseases and allergic reactions to Loteprednol+tobramycin and its components. Avoid touching the eye dropper with bare hands or taking it closer to the eyelids while administering drops since it contaminates the dropper tip and solution. Avoid driving or operating machines since the administration of Loteprednol+tobramycin causes blurred vision for a while after using. If you are pregnant or a breastfeeding mother, please consult your doctor before using Loteprednol+tobramycin.

Uses of Loteprednol+tobramycin

Bacterial eye infections.

Medicinal Benefits

Loteprednol+tobramycin treats and prevents bacterial eye infections and contains two medicines, namely: Tobramycin (antibiotic) and Loteprednol (corticosteroid). Tobramycin is an aminoglycoside antibiotic that inhibits bacteria growth by interfering with protein synthesis. It binds to the bacteria's proteins, disrupting the cell membrane, and eventually leading to cell death. Loteprednol, a corticosteroid, blocks prostaglandins' production (chemical messengers) that make the eye red, swollen and itchy. Loteprednol+tobramycin is used to prevent or treat only bacterial eye infections.

Directions for Use

Eye drops: Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops as advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Loteprednol+tobramycin

  • Blurred vision
  • Burning/stinging sensation of the eye 
  • Eye discomfort 

Patients Concern

Disease/Condition Glossary

Bacterial eye infection: A bacterial eye infection occurs when bacteria invade any part of the eyeball or its surrounding tissues, including the cornea (clear front surface of the eye) and the conjunctiva (thin membrane lining the outer eye and inner eyelids). A bacterial eye infection symptoms include red eyes, pain, swelling of eyes, watery eyes, itching, and blurry vision. Some prevalent/very common eye infections are Conjunctivitis (pink eye) and Stye.

Conjunctivitis: A condition caused by the inflammation and irritation of the eye's mucous membrane (conjunctiva). 

Stye: Formation of a bump on the eyelid that happens when bacteria from the skin get into an eyelash's hair follicle.

FAQs

Loteprednol+tobramycin contains Tobramycin and Loteprednol. Tobramycin, an antibiotic, binds to the bacteria's proteins, disrupting the cell membrane, and leading to cell death. Loteprednol, a corticosteroid, blocks prostaglandins' production (chemical messengers) that make the eye red, swollen and itchy. Collectively, Loteprednol+tobramycin helps in relieving and treating symptoms of bacterial eye infections.

If you use other eye ointments/drops along with Loteprednol+tobramycin, it is advised to maintain a gap of at least 5-10 minutes after each administration. Also, use eye drops before applying any eye ointment.

Loteprednol+tobramycin can cause a blurry vision for some time in the beginning. Avoid driving and operating machinery in such cases until you feel better. If the effect persists longer, seek medical attention.

Avoid the contact of the dropper or tip with fingers, eyes, and eyelids when you use eye ointment or eye drops. Topical eye products, when contaminated by patients with eye diseases, bacterial keratitis (an infection of the cornea) and ocular infections (eye infections) may occur, which result in vision loss.

It is advised to remove your contact lens if you are wearing it while administering Loteprednol+tobramycin. Also, remember to wash your hands before and after administering the medicine to avoid contamination.

Available Medicines for

Loteprednol+tobramycin

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