Linagliptin+metformin
About Linagliptin+metformin
Linagliptin+metformin is a combination drug of Linagliptin (DPP4 inhibitors) and Metformin (Biguanides) belongs to the anti-diabetic class. Type 2 diabetes is a condition in which either the body stops producing enough insulin (the hormone which helps to decrease sugar levels in the blood) or resistance to insulin action. As a result, insulin is produced in large amounts but cannot act on the body's organs.
Linagliptin+metformin contains Linagliptin (DPP4 inhibitors) and Metformin (Biguanide). Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that blocks the action of DPP-4, an enzyme that destroys the hormone incretin that helps the body produce more insulin only when required. It also reduces the amount of sugar produced by the liver when not needed. Metformin functions by lowering glucose production in the liver, delaying glucose absorption from the intestines and increasing the body's sensitivity to insulin. Together, it prevents blood glucose levels from rising to very high levels after meals.
Linagliptin+metformin should be taken with food to avoid an upset stomach. Linagliptin+metformin should be taken at the same time of the day each time for the best results. Your doctor will decide what dose should be taken for better advice, which can change quickly depending on your condition. The most common side effect of Linagliptin+metformin is hypoglycemia (low blood glucose levels) characterized by dizziness, sweating, palpitations, hunger pangs, dry mouth, skin, etc. So to avoid hypoglycemia, you should not miss meals and should carry some form of sugar along with you. Other side effects include taste change, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms.
Linagliptin+metformin should not be stopped even if you feel better without consulting your doctor as the sugar level keeps changing. If you stop taking Linagliptin+metformin abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy), and nerve damage (neuropathy). Linagliptin+metformin should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease. Please inform your doctor if you have heart disease or are planning to get pregnant or breastfeed.
Uses of Linagliptin+metformin
Medicinal Benefits
Linagliptin+metformin helps your pancreas produce more insulin, make effective insulin utilization, and decrease the excess sugar that your liver makes. It helps control the rise of blood sugar levels in your body after a meal. Besides this, it does not cause weight gain in prolonged use. Linagliptin+metformin plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer, and delayed wound healing.
Directions for Use
Storage
Side Effects of Linagliptin+metformin
- Low blood sugar
- Runny nose
- Sore throat
- Upper lung infection
- Diarrhoea
- Nausea
- Vomiting
- Gas
- Stomach upset
- Indigestion,
- General weakness
- Headache
Patients Concern
Disease/Condition Glossary
Type 2 diabetes is a condition where the body cannot make sufficient insulin, or the insulin that it makes doesn't work properly or is utilized by our body. This can cause high blood sugar levels (hyperglycemia). Type 2 diabetes symptoms include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, and blurred vision. There may be weight gain in some cases, while weight loss may be observed in rare cases. The complication of type 2 diabetes also includes neuropathy (nerve problems), nephropathy (kidney problems), and retinopathy (damaged retina of eyes or blindness), loss of limbs, sexual dysfunction, and increase the chance of heart attack or stroke.
FAQs
Linagliptin+metformin contains Linagliptin (DPP4 inhibitors) and Metformin (Biguanide). Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that blocks the action of DPP-4, an enzyme that destroys the hormone incretin that helps the body produce more insulin only when required. It also reduces the amount of sugar produced by the liver when not needed. Metformin functions by lowering glucose production in the liver, delaying glucose absorption from the intestines and increasing the body's sensitivity to insulin. Together, it prevents blood glucose levels from rising to very high levels after meals.
Type 2 diabetes is a common form of diabetes in which the blood sugar-lowering hormone called insulin produced by the body does not function properly. Thus, the blood glucose level increases, and symptoms such as frequent urination, increased thirst, and increased hunger start. Diabetes, if left untreated or not treated properly, can cause long-term complications such as nerve damage, kidney damage, eye damage, foot problems, and poses a high risk of developing heart diseases.
Lactic acidosis is a rare but life-threatening condition when there is too much lactic acid built up in the bloodstream. Long term intake of Linagliptin+metformin may lead to lactic acidosis when cells get deprived of oxygen levels. Lactic acidosis symptoms include a burning sensation of muscle, muscle ache, fast breathing, nausea, and stomach pain. Immediately contact the doctor about this complication.
Do not take excessive alcohol while taking Linagliptin+metformin, as this may increase the risk of a life-threatening condition called lactic acidosis (too much lactic acid in the body).
No, Linagliptin+metformin is only prescribed to treat type 2 diabetes, also called 'non-insulin-dependent diabetes.'
Linagliptin+metformin should be given with caution in older adults as they are at an increased risk of hypoglycemia. Consult your doctor; dose adjustment may be required, and take Linagliptin+metformin in dose as prescribed by your doctor.
If you feel that your blood sugar level is decreasing and you are feeling weak, immediately eat sugar candies or drink sugary beverages. It will help to balance the blood sugar level in your body. So, it is advisable to keep sugar candies with you.
