Pioglitazone+metformin+glimepiride
About Pioglitazone+metformin+glimepiride
Glimepiride+metformin+pioglitazone belongs to the group of medications called ‘antidiabetic agents’ used in the treatment of Type 2 diabetes mellitus. Type 2 diabetes mellitus is a chronic or life-long condition in which blood sugar or glucose levels rise more than normal. It occurs when the body does not produce enough insulin (metabolizes glucose), or if produced, it cannot function properly in the body.
Glimepiride+metformin+pioglitazone is a combination of three medicines, namely: Metformin, Glimepiride, and Pioglitazone. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Glimepiride acts by increasing the amount of insulin released by the pancreas. Pioglitazone works by decreasing the amount of glucose released by the liver and also by improving the sensitivity of tissues towards insulin effects.
You should take this medicine as prescribed by your doctor. You may experience side-effects of such as nausea (feeling sick), vomiting (falling sick), diarrhea, headache, stomach ache, respiratory infection, weight gain, sweating, palpitations, and vision problems. Some patients experience decline in blood sugar levels lower than normal (hypoglycemia) resulting in sweating, dizziness, headache, confusion, feeling hungry, temporary changes in vision, uneasiness, irritability, and weakness. In such cases, seek medical attention immediately.
Do not take Glimepiride+metformin+pioglitazone if you are allergic to any of its contents. Do not use this medicine if you have heart failure, bladder cancer, or diabetic ketoacidosis (a complication of diabetes). Glimepiride+metformin+pioglitazone may cause ‘lactic acidosis’ (accumulation of lactic acid in the blood), which requires immediate medical attention. The risk increases if you are previously diagnosed with kidney or liver diseases. Do not consume alcohol (risk of lactic acidosis) or fast for prolonged periods (risk of hypoglycemia). Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Uses of Pioglitazone+metformin+glimepiride
Medicinal Benefits
Glimepiride+metformin+pioglitazone contains Metformin, Glimepiride, and Pioglitazone. Glimepiride+metformin+pioglitazone is given when single or dual therapy of hypoglycemic agents is not effective in diabetes patients. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Glimepiride acts by increasing the secretion of insulin by the pancreas. Pioglitazone works by decreasing the amount of glucose released by the liver and improving insulin sensitivity in muscle and fat.
Directions for Use
Storage
Side Effects of Pioglitazone+metformin+glimepiride
- Nausea (feeling sick)
- Vomiting (falling sick)
- Diarrhea
- Headache
- Stomach ache
- Respiratory infection
- Weight gain
- Sweating
- Palpitations
- Numbness
- Vision problems
Patients Concern
Disease/Condition Glossary
Type 2 diabetes mellitus: It is a chronic condition in which blood glucose levels are elevated in the body. Insulin is responsible for the utilization of glucose by the cells. In type 2 diabetes, the body cells do not respond to insulin, or in later stages, your body may not produce enough insulin. Symptoms include excessive thirst, excessive hunger, fatigue, increased appetite, and dry mouth. This condition may worsen over time and cause toxic effects if not properly treated.
FAQs
Glimepiride+metformin+pioglitazone is a combination of three antidiabetic medicines, Metformin, Glimepiride, and Pioglitazone. It works by increasing insulin production, helping to restore your body's appropriate response to insulin, especially muscle and fatty tissues, thereby lowering your elevated blood sugar levels.
Patients with type 2 diabetes who have congestive heart failure, kidney problems, liver problems, vision problems, or diabetic ketoacidosis should not take Glimepiride+metformin+pioglitazone. It is also not given to pregnant, breastfeeding, or a premenopausal woman.
Hypoglycemia refers to low blood glucose levels. Glimepiride+metformin+pioglitazone may cause hypoglycemia. Hypoglycemia can occur if you miss or delay your food, drink alcohol, intense exercise, or take other antidiabetic medicine along with this medicine. So, take your medicine as advised by your doctor to avoid any unwanted effects of this medicine.
If you feel that your blood sugar levels are dropping, eat glucose tablets or chocolate immediately. This will help to increase your sugar levels instantly. So, it is always advised to carry glucose tablets or sugar candies with you.
Yes, type 2 diabetes may also occur in children. The risk increases if the child is overweight or obese.
You may experience high blood sugar, symptoms such as increased thirst and hunger, frequent urination, weight loss, delayed wound healing, and frequent infections. Consult a doctor or endocrinologist to confirm the diagnosis.