Glibenclamide+metformin+rosiglitazone
About Glibenclamide+metformin+rosiglitazone
Glibenclamide+metformin+rosiglitazone belongs to a class of medicines called antidiabetic drugs used in the treatment of type 2 diabetes, especially in patients whose blood sugar levels are not controlled by diet and exercise alone. Type 2 diabetes is a chronic (long-lasting) condition that affects the way our body processes glucose. People with type 2 diabetes either do not produce enough insulin or the insulin produced is unable to perform its function in the body (insulin resistance).
Glibenclamide+metformin+rosiglitazone is a combination of three antidiabetic drugs, namely: Glibenclamide, Metformin, and Rosiglitazone. Glibenclamide works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Rosiglitazone works by increasing the sensitivity of liver, muscle, and fat cells to insulin and enables cells to remove glucose from blood more effectively. Thereby, Glibenclamide+metformin+rosiglitazone helps to control blood sugar levels.
Take Glibenclamide+metformin+rosiglitazone as prescribed by your doctor. You are advised to take Glibenclamide+metformin+rosiglitazone for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience stomach pain, nausea, diarrhea, vomiting, headache, or low blood sugar. Most of these side effects of Glibenclamide+metformin+rosiglitazone do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Glibenclamide+metformin+rosiglitazone or any other medicines, please tell your doctor. Glibenclamide+metformin+rosiglitazone is not recommended for children below 18 years of age. Avoid breastfeeding while taking Glibenclamide+metformin+rosiglitazone as it may be excreted in human milk. If you are pregnant or planning for pregnancy, please inform your doctor before taking Glibenclamide+metformin+rosiglitazone as it may harm an unborn baby. Glibenclamide+metformin+rosiglitazone should be used with caution in elderly patients. Avoid alcohol consumption with Glibenclamide+metformin+rosiglitazone as it may increase the risk of lactic acidosis (accumulation of lactic acid in the body). Drive only if you are alert after taking Glibenclamide+metformin+rosiglitazone.
Uses of Glibenclamide+metformin+rosiglitazone
Medicinal Benefits
Glibenclamide+metformin+rosiglitazone contains three antidiabetic drugs (Glibenclamide, Metformin, and Rosiglitazone) used in the treatment of type 2 diabetes. Glibenclamide stimulates cells in the pancreas that produce insulin which helps to remove sugar from the blood. Metformin reduces sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood. Rosiglitazone increases the sensitivity of liver, muscle, and fat cells to insulin and enables cells to remove glucose from blood more effectively. Also, it decreases the amount of glucose produced by the liver and preserves the functioning of beta cells in the pancreas that produce insulin. Thereby, Glibenclamide+metformin+rosiglitazone helps to control blood sugar levels.
Directions for Use
Storage
Side Effects of Glibenclamide+metformin+rosiglitazone
- Stomach pain
- Nausea
- Diarrhoea
- Vomiting
- Headache
- Low blood sugar
Patients Concern
Disease/Condition Glossary
Type 2 diabetes: It is a chronic (long-lasting) condition that keeps the body away from properly utilizing insulin. Hence, people affected with type 2 diabetes either do not produce enough insulin, or there is resistance to the action of insulin. Middle-aged or older are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes. Symptoms of type 2 diabetes include frequent urination at night, increased thirst, slow wound healing, increased hunger, fatigue, and blurred vision. In some cases, there may be weight gain while in rare cases weight loss may be observed. The complication of type 2 diabetes also includes nerve problems, kidney problems, the damaged retina of eyes or blindness, loss of limbs, sexual dysfunction, and increase the chance of heart attack or stroke.
FAQs
Glibenclamide+metformin+rosiglitazone contains Glibenclamide, Metformin and Rosiglitazone. Glibenclamide works by stimulating beta cells in the pancreas that produce insulin. Thus, insulin helps to remove sugar from the blood. Metformin works by reducing the sugar production by cells in the liver and delays sugar absorption from the intestines. Also, it increases the sensitivity of muscle cells to insulin which enables these cells to remove sugar more effectively from the blood. Rosiglitazone works by increasing the sensitivity of liver, muscle and fat cells to insulin and enables cells to remove glucose from blood more effectively. Thereby, Glibenclamide+metformin+rosiglitazone helps to control blood sugar levels.
Glibenclamide+metformin+rosiglitazone may increase the risk of low blood sugar levels, especially with alcohol intake, when you exercise more than usual, delay or miss snacks or meal. However, if you experience any signs of low blood pressure such as dizziness, nausea, light-headedness, dehydration or fainting, please consult a doctor.
You are not recommended to take Glibenclamide+metformin+rosiglitazone with levothyroxine as it may reduce the hypoglycemic (lowering blood sugar levels) effect of metformin. However, please consult a doctor before using Glibenclamide+metformin+rosiglitazone with other medicines.
In type 1 diabetes, the body doesn’t produce insulin as the islet cells (insulin-producing cells) in the pancreas are destroyed completed. In type 2 diabetes, though islet cells are working, the body doesn’t respond to insulin as the body becomes resistant to insulin.
You are not recommended to stop taking Glibenclamide+metformin+rosiglitazone on your own as discontinuing Glibenclamide+metformin+rosiglitazone suddenly may cause recurring symptoms or worsen the condition. However, if you experience any difficulty while taking Glibenclamide+metformin+rosiglitazone, please consult your doctor so that alternative medicine may be prescribed.
