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Phenylephrine+dextromethorphan+cetirizine+menthol

About Phenylephrine+dextromethorphan+cetirizine+menthol

Cetirizine+dextromethorphan+menthol+phenylephrine belongs to the class of medications called 'cough and cold preparations' primarily used to treat dry cough. In addition to this, it also helps to treat allergic symptoms like runny nose, watery eyes, sneezing, throat irritation. Cough is a reflex action that helps to clear any foreign irritant or mucus in the throat. Mostly cough lasts for a short time (two to three weeks), so it is acute. But sometimes, if it is persistent for more than eight weeks which can lead to chronic cough. Dry cough refers to cough where there is no mucus or secretion along with cough.

Cetirizine+dextromethorphan+menthol+phenylephrine is composed of four medicines, namely: Cetirizine (antihistamine/antiallergic), Phenylephrine (decongestant), Dextromethorphan (cough suppressant) and menthol (cooling/soothing agent). Cetirizine belongs to the class of antihistamines (antiallergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion or stiffness. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing stuffy nose. Dextromethorphan works by blocking the cough receptor present in the brain, which is known to cause cough. Menthol is an additive that acts as a cooling agent that relieves minor irritation in the throat. 

Cetirizine+dextromethorphan+menthol+phenylephrine is available in liquid form (syrup). Your doctor will recommend how often you take Cetirizine+dextromethorphan+menthol+phenylephrine based on your medical condition. The dose of Cetirizine+dextromethorphan+menthol+phenylephrine should be measured with a measuring cup and not with a spoon to avoid dose fluctuations. Some people may experience an upset stomach, skin rash, flushing of the skin, drowsiness, insomnia (difficulty in sleeping), itching, loss of appetite. Everyone doesn't need to experience the above side effects.

Inform your doctor if you are pregnant, planning for pregnancy, or breastfeeding before starting Cetirizine+dextromethorphan+menthol+phenylephrine. If you have high blood pressure (hypertension),  liver or kidney disease, coronary artery disease (heart disease), avoid using Cetirizine+dextromethorphan+menthol+phenylephrine as it may worsen your existing condition and symptom. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness. Do not take Cetirizine+dextromethorphan+menthol+phenylephrine if you have taken MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the last 14 days. Phenylephrine present in Cetirizine+dextromethorphan+menthol+phenylephrine should be used with caution in patients with occlusive vascular disease (nerve/artery blockage), including Raynaud's phenomenon (decreased blood flow to the fingers). 

Uses of Phenylephrine+dextromethorphan+cetirizine+menthol

Dry cough

Medicinal Benefits

Cetirizine+dextromethorphan+menthol+phenylephrine is primarily used to treat dry cough, which is composed of four medicines, namely: Cetirizine (antihistamine/antiallergic), Phenylephrine (decongestant), Dextromethorphan (cough suppressant) and menthol. Cetirizine belongs to the class of antihistamines (antiallergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing stuffy nose. Dextromethorphan works by blocking the cough receptor present in the brain, which is known to cause cough. Menthol is an additive that helps to relieve minor irritation in the throat and produces a cooling sensation.

Directions for Use

Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Phenylephrine+dextromethorphan+cetirizine+menthol

  • Upset stomach
  • Skin rash
  • Flushing of the skin
  • Drowsiness
  • Insomnia (difficulty in sleeping)
  • Itching
  • Loss of appetite

Drug Warnings

Do not take Cetirizine+dextromethorphan+menthol+phenylephrine if you are allergic to Cetirizine+dextromethorphan+menthol+phenylephrine, anti-histamine (cetirizine), a decongestant (phenylephrine), a cough suppressant (dextromethorphan), or any of its ingredients. Please inform your doctor if you are pregnant or breastfeeding before starting Cetirizine+dextromethorphan+menthol+phenylephrine. If you have high blood pressure,  kidney or liver disease, coronary artery disease, please do not take Cetirizine+dextromethorphan+menthol+phenylephrine as it is known to interact. Also, inform your doctor about all other medications you have been taking before starting Cetirizine+dextromethorphan+menthol+phenylephrine. Do not stop taking Cetirizine+dextromethorphan+menthol+phenylephrine even if you feel better without asking your doctor as your symptoms may come back and may even worsen your condition. Cetirizine+dextromethorphan+menthol+phenylephrine may cause drowsiness and sleepiness, so it is advised not to drive a car or operate machinery. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness. Do not take Cetirizine+dextromethorphan+menthol+phenylephrine if you have taken any MAO inhibitor (anti-depressant medication like Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine) in the past 14 days. Also, avoid tobacco consumption as it may worsen your condition further.

Drug Interactions

Drug-Drug Interaction: Cetirizine+dextromethorphan+menthol+phenylephrine may interact with MAO inhibitor (isocarboxazid, phenelzine, rasagiline, selegiline, tranylcypromine), anti-arrhythmic medications (amiodarone, propafenone, quinidine, and flecainide), opioid analgesics (codeine, tramadol, morphine, methadone), anti-anxiety medications (fluoxetine, paroxetine, sertraline), anti-fungal (terbinafine), blood thinners (warfarin, aspirin), anti-allergic drugs (diphenhydramine), anti-depressants (alprazolam, amitriptyline, amoxapine, clomipramine, doxepin), anticonvulsants (fosphenytoin, levetiracetam, phenytoin, valproic acid), HIV medications (lopinavir, ritonavir, saquinavir), antipsychotics (chlorpromazine, clozapine), diabetes medications (metformin, glimepiride, glipizide), and heart medications (digoxin).

Drug-Food Interaction: Avoid alcohol intake and tobacco consumption with Cetirizine+dextromethorphan+menthol+phenylephrine as it may cause increased drowsiness, dizziness, and lack of concentration.

Drug-Disease Interaction: If you have high blood pressure, kidney or liver problems, coronary artery disease, sinus (nasal congestion), diabetes, enlarged prostate, kidney or liver disease, overactive thyroid, high blood pressure (hypertension), glaucoma (increased eye pressure), are receiving monoamine oxidase inhibitor (MAO) therapy, inform your doctor before taking Cetirizine+dextromethorphan+menthol+phenylephrine.

 

Drug-Drug Interactions Checker List:

  • ISOCARBOXAZID
  • PHENELZINE
  • RASAGILINE
  • SELEGILINE
  • TRANYLCYPROMINE
  • AMIDODARONE
  • PROPAFENONE
  • QUINIDINE
  • FLECAINIDE
  • CODEINE
  • TRAMADOL
  • MORPHINE
  • METHADONE
  • FLUOXETINE
  • PAROXETINE
  • SERTRALINE
  • TERBINAFINE
  • WARFARIN
  • ASPIRIN
  • DIPHENHYDRAMINE
  • ALPRAZOLAM
  • AMITRIPTYLINE
  • AMOXAPINE
  • CLOMIPRAMINE
  • DOXEPIN
  • FOSPHENYTOIN
  • LEVETIRACETAM
  • PHENYTOIN
  • VALPROIC ACID
  • LOPINAVIR
  • RITONAVIR
  • SAQUINAVIR
  • CHLORPROMAZINE
  • CLOZAPINE
  • METFORMIN
  • GLIMEPIRIDE
  • GLIPIZIDE
  • DIGOXIN
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol with Cetirizine+dextromethorphan+menthol+phenylephrine as it may increase drowsiness. Please consult a doctor before consuming alcohol with Cetirizine+dextromethorphan+menthol+phenylephrine.

    • Safety Warning

      Pregnancy

      caution

      The safety of Cetirizine+dextromethorphan+menthol+phenylephrine in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      The safety of Cetirizine+dextromethorphan+menthol+phenylephrine in breastfeeding mothers is unknown. Therefore, it is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

    • Safety Warning

      Driving

      unsafe

      Cetirizine+dextromethorphan+menthol+phenylephrine may cause drowsiness or tiredness in some people. Therefore, drive only if you are alert after taking Cetirizine+dextromethorphan+menthol+phenylephrine.

    • Safety Warning

      Liver

      caution

      Take Cetirizine+dextromethorphan+menthol+phenylephrine with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Kidney

      caution

      Take Cetirizine+dextromethorphan+menthol+phenylephrine with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Children

      caution

      Cetirizine+dextromethorphan+menthol+phenylephrine is not recommended for children below 12 years of age. However, please consult a doctor before giving Cetirizine+dextromethorphan+menthol+phenylephrine to children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Wash your hands with soap and water regularly to prevent the spread of germs.
    • Eat plenty of foods rich in good bacteria like yogurt to improve overall health.
    • Drink plenty of fluids to avoid dehydration.
    • Gargle with salt water for relief from sore throat.
    • Do not smoke as it might worsen your symptoms, so avoid tobacco intake.
    • Avoid alcohol consumption with Cetirizine+dextromethorphan+menthol+phenylephrine as it may cause tiredness, drowsiness, or lack of concentration.

    Special Advise

    • Avoid alcohol consumption with Cetirizine+dextromethorphan+menthol+phenylephrine as it may cause tiredness, drowsiness, or lack of concentration. 
    • Do not take Cetirizine+dextromethorphan+menthol+phenylephrine if you have taken an MAO inhibitor (anti-depressant medication) in the past 14 days.
    • Please inform your doctor if you are pregnant or breastfeeding before starting Cetirizine+dextromethorphan+menthol+phenylephrine.
    • Smoking may further worsen your condition, so avoid tobacco consumption.

    Patients Concern

    Disease/Condition Glossary

    Cough: It is a reflex action that helps to clear any foreign irritant or mucus in the throat. Mostly cough lasts for a short time (two to three weeks), so it is acute. But sometimes, if it is persistent for more than eight weeks which can lead to chronic cough. If the cough is accompanied by blood or barking cough, this could be serious and require medical attention. The most common causes of cough are cold/flu, asthma, emphysema, COPD (chronic obstructive pulmonary disease). Also, some medications, especially angiotensin-converting enzyme inhibitors used for hypertension, are known to cause cough.

    Allergies: This is a condition that occurs when allergy-causing agents known as 'allergens' attack our body, thereby causing symptoms like redness, stuffy nose, watery eyes, excess mucus formation, airways irritation, itchy and watery nasal passage/throat. During the allergic condition, our body secretes many chemical messengers called 'histamines,' which in turn cause all these allergic symptoms. Allergies can be caused due to various chemicals, air pollutants, dust, pollen grains of plants, pet danders, hairs and various medicines. 

    FAQs

    Cetirizine+dextromethorphan+menthol+phenylephrine is primarily used to treat dry cough. It is composed of four medicines, namely: Cetirizine (antihistamine/antiallergic), Phenylephrine (decongestant), and Dextromethorphan (cough suppressant) and menthol. Cetirizine belongs to the class of antihistamines (antiallergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion or stiffness. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing stuffy nose. Dextromethorphan works by blocking the cough receptor present in the brain, which is known to cause cough. Menthol is an additive that helps to relieve minor irritation in the throat and produces a cooling sensation.

    It is not recommended to take Cetirizine+dextromethorphan+menthol+phenylephrine along with any anti-depressant medication as it contains dextromethorphan and phenylephrine, which may cause unpleasant side-effects or any drug interaction. Also, Cetirizine+dextromethorphan+menthol+phenylephrine should be taken at least 15 days after your last dose of anti-depressants, especially monoamine oxidase inhibitors (MAO).

    No, you are not recommended to stop taking Cetirizine+dextromethorphan+menthol+phenylephrine without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Cetirizine+dextromethorphan+menthol+phenylephrine for as long as your doctor has prescribed it, and if you experience any difficulty while taking Cetirizine+dextromethorphan+menthol+phenylephrine, please consult your doctor.

    No, it would be best if you did not take Cetirizine+dextromethorphan+menthol+phenylephrine along with high blood pressure (hypertension) medication, leading to a further rise in blood pressure. Please inform your doctor if you have high blood pressure before starting Cetirizine+dextromethorphan+menthol+phenylephrine.

    Yes, Cetirizine+dextromethorphan+menthol+phenylephrine may cause drowsiness. It is not necessary for everyone taking Cetirizine+dextromethorphan+menthol+phenylephrine to experience this side effect. Therefore, avoid driving if you feel drowsy after taking Cetirizine+dextromethorphan+menthol+phenylephrine.

    Available Medicines for

    Phenylephrine+dextromethorphan+cetirizine+menthol

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