Ceftazidime+avibactam
About Ceftazidime+avibactam
Ceftazidime+avibactam belongs to a class of medicines called antibiotics used in the treatment of bacterial infections of the urinary tract, respiratory tract and abdomen. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. Bacteremia is the presence of bacteria in the blood.
Ceftazidime+avibactam contains Ceftazidime and Avibactam. Ceftazidime works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. Avibactam decreases bacterial resistance and enhances the activity of Ceftazidime against the bacteria. Together, Ceftazidime+avibactam helps to treat bacterial infections.
In some cases, you may experience redness and swelling at the site of injection, and/or nausea and diarrhoea. Most of these side effects of Ceftazidime+avibactam do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to Ceftazidime+avibactam or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Ceftazidime+avibactam. Drive only if you are alert as Ceftazidime+avibactam may cause dizziness. Ceftazidime+avibactam should be used with caution in those with renal impairment and Clostridium difficile-associated diarrhoea.
Uses of Ceftazidime+avibactam
Medicinal Benefits
Ceftazidime+avibactam contains Ceftazidime and Avibactam; they act against both aerobic (grow in the presence of oxygen) and anaerobic (grow in the absence of oxygen) gram-negative and gram-positive bacteria. It is used in the treatment of bacterial infections of the urinary tract, respiratory tract, and abdomen. Ceftazidime inhibits enzymes that regulate the formation of the bacterial cell wall, thereby arresting bacterial development. Avibactam is a beta-lactamase inhibitor. Beta-lactamase is an enzyme that inactivates antibiotics and builds up a drug resistance. By inhibiting beta-lactamase, avibactam makes the bacteria more susceptible to antibiotic action. Ceftazidime+avibactam damages the bacterial cell wall, kills bacteria and makes the bacteria more sensitive to the action of the antibiotic. Hence Ceftazidime+avibactam finds widespread use in treating complicated bacterial infections.
Directions for Use
Storage
Side Effects of Ceftazidime+avibactam
- Redness and swelling on injection site
- Diarrhoea
- Dizziness
- Nausea
Patients Concern
Disease/Condition Glossary
Bacterial Infection: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When you get infected with bacteria, you can experience generalized symptoms, like fevers, chills, and fatigue.
FAQs
Ceftazidime+avibactam works by damaging the bacterial cell wall (protective covering) that is necessary for their survival and by increasing bacterial sensitivity.
Ceftazidime+avibactam may cause diarrhoea as a common side effect. However, if the condition persists, worsens or if you notice blood or mucus in stools, avoid taking Ceftazidime+avibactam and consult a doctor immediately.
Exercise caution while taking Ceftazidime+avibactam with diuretics/water tablets. You are not advised to take Ceftazidime+avibactam with a diuretic called furosemide as co-administration of these two medicines may increase the risk of kidney problems, especially in patients with kidney impairment and also when Ceftazidime+avibactam is given in high doses. However, please consult your doctor before taking Ceftazidime+avibactam with other medicines.
Ceftazidime+avibactam is not used to treat viral infections. Ceftazidime+avibactam is an antibiotic that is used to treat only bacterial infections.
