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Lidocaine+adrenaline

About Lidocaine+adrenaline

Adrenaline+lidocaine belongs to the class of local anaesthetics known as numbing medication used to produce local numbness (anaesthesia) on skin before surgical procedure and reduce pain and discomfort caused by invasive medical procedures such as surgery. It is also used to reduce the discomfort of contractions during labour. Adrenaline+lidocaine is also used to treat certain types of chronic pain. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or may come and go. The tolerance level of pain might vary from person to person.

Adrenaline+lidocaine is a combination of two drugs: Lidocaine (local anesthetic) and Adrenaline (vasoconstrictor). Lidocaine works by blocking the influx (entry) of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses. Hence, it gives an anaesthetic effect and helps decrease the sensation of pain. Adrenaline works by constricting and narrowing blood vessels to slow the dispersal. Thereby prolong the effect of Lidocaine.

Adrenaline+lidocaine will be administered by a healthcare professional. Do not self-administer. In some cases, you may experience certain common side-effects such as reactions at the application site (burning, itching, redness, and irritation), nausea, vomiting and allergy. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

The usage of Adrenaline+lidocaine is not allowed in patients who are hypersensitive to any of the components present in it as it may cause serious side effects.  Before starting the medication, tell your doctor about your medical history, especially if you have high blood pressure or heart problems such as a slow heart beat, hypovolaemia (decreased volume of blood), epilepsy, diabetes, liver disease, a certain blood disorder (methemoglobinemia). Please consult a doctor if you are pregnant or breastfeeding before taking Adrenaline+lidocaine. Adrenaline+lidocaine is not recommended for children. 

Uses of Lidocaine+adrenaline

Pain relief (local anaesthesia).

Medicinal Benefits

Adrenaline+lidocaine is a combination of two medicines, namely; Lidocaine (local anesthetic) and Adrenaline (vasoconstrictor). Adrenaline+lidocaine is used to produce local numbness (anaesthesia). Lidocaine is a local anesthetic which works by blocking the transmission of the nerve signals in the body, thereby helps in decreasing the sensation of pain. Adrenaline is a vasoconstrictor which works by constricting and narrowing blood vessels to slow the dispersal. Thereby prolong the effect of Lidocaine. Adrenaline+lidocaine is used to reduce pain and discomfort caused by invasive medical procedures such as surgery, needle punctures or insertion of a breathing tube or catheter. It is also used to reduce the discomfort of contractions during labour. Adrenaline+lidocaine will start to work rapidly after being injected and will slowly wear off when the surgical procedure is over.

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Lidocaine+adrenaline

  • Pale skin
  • Burning sensation
  • Stinging sensation
  • Erythema (skin redness)
  • Itching
  • Pain at the site of application
  • Petechiae (red or purple spot caused by bleeding into the skin)

Drug Warnings

Do not exceed the dose and duration prescribed by your doctor. Consult your doctor before taking Adrenaline+lidocaine if you are pregnant or breastfeeding, your doctor will prescribe you Adrenaline+lidocaine only if the benefits outweigh the risks. Adrenaline+lidocaine causes drowsiness, so drive with caution. Avoid consuming alcohol along with Adrenaline+lidocaine as it could lead to increased drowsiness. Adrenaline+lidocaine may not be suitable for people with respiratory disease, heart disease, epilepsy, low blood pressure, kidney or liver problems. Inform your doctor about your health condition and medications before taking Adrenaline+lidocaine to rule out any side-effects.

Drug Interactions

Drug-Drug Interaction: Adrenaline+lidocaine may have interaction with used to treat anxiety (lorazepam, alprazolam), medicines used to induce anaesthesia (halothane, prilocaine), a medicine used to relieve pain (tramadol), medicines used to treat an uneven heartbeat (arrhythmia) and hypertension (amiodarone,  propranolol, sodium nitrite), medicines for sickness (domperidone), medicines for mental problems (haloperidol, chlorpromazine) antidepressants (isocarboxazid, phenelzine, selegiline, tranylcypromine), antiulcer (cimetidine).

Drug-Food Interaction: Avoid consuming alcohol along with Adrenaline+lidocaine as it could lead to increased drowsiness.

Drug-Disease Interaction: Adrenaline+lidocaine may interact with heart dysfunction, seizures (fits), electrolyte imbalance, liver problems and kidney dysfunction.

Drug-Drug Interactions Checker List:

  • LORAZEPAM
  • ALPRAZOLAM
  • HALOTHANE
  • PRILOCAINE
  • TRAMADOL
  • AMIODARONE
  • PROPRANOLOL
  • SODIUM NITRITE
  • DOMPERIDONE
  • CIMETIDINE
  • ISOCARBOXAZID
  • PHENELZINE
  • SELEGILINE
  • TRANYLCYPROMINE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      You are recommended to avoid alcohol consumption while taking Adrenaline+lidocaine. Alcohol intake, along with Adrenaline+lidocaine, may cause increased drowsiness.

    • Safety Warning

      Pregnancy

      unsafe

      It is not recommended to take Adrenaline+lidocaine while you are pregnant. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe you Adrenaline+lidocaine only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      unsafe

      Please consult your doctor if you have any concerns regarding this, your doctor will decide whether breastfeeding mothers can take Adrenaline+lidocaine or not.

    • Safety Warning

      Driving

      caution

      Adrenaline+lidocaine may cause drowsiness and vision disturbances, do not drive or operate heavy machinery if you feel drowsy.

    • Safety Warning

      Liver

      caution

      Adrenaline+lidocaine should be used with caution in patients with liver impairment/liver disease. Dose adjustment may be needed. Please consult your doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Adrenaline+lidocaine should be used with caution in patients with kidney impairment/kidney disease. Dose adjustment may be needed. Please consult your doctor if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      unsafe

      Adrenaline+lidocaine should not be used by children, as the efficacy and safety have not been established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • ​Indulge yourself in mindfulness activities like yoga that help in reducing stress levels and pain management.
    • Never forget to get about 7-8 hours of sleep as it will help your muscles to heal fast and reduces inflammation and swelling.
    • Take out some time for meditation, read books, take a warm bubble bath, spend time with family or listen to relaxing music.
    • Make a habit of eating food rich in antioxidants such as berries, onion, milk, spinach, kidney beans, dark chocolate, etc.
    • Foods rich in flavonoids helps the body to heal faster by reducing inflammation. These include soy, berries, broccoli, grapes and green tea.
    • Strictly limit smoking and alcohol consumption as it may worsen the side effects of the drug.

    Special Advise

    Inform your doctor about any blood diseases/problems like hypovolaemia (decreased volume of blood), heart problems such as a slow heart beat, difficulty breathing or ever had a stroke.

    Patients Concern

    Disease/Condition Glossary

    Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). Pain can be considered a good thing as it helps us know that something is wrong in the body and thereby helps diagnose the condition. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, arthritis and stomach ache.

    FAQs

    Adrenaline+lidocaine contains Lidocaine and Adrenaline. Lidocaine blocks the influx of sodium ions into the membrane that surrounds the nerves, thereby preventing initiation and conduction of impulses (nerve signal). Hence, it gives an anesthetic effect and decreases the sensation of pain. Adrenaline works by constricting and narrowing blood vessels by acting on alpha receptors that cause muscle contractions. Thus, it decreasing the bleeding and the effects of Adrenaline+lidocaine will last longer.

    You are not recommended to take duloxetine (antidepressant) with Adrenaline+lidocaine as co-administration of these two medicines may increase the risk of high blood pressure and heart rate. However, please consult your doctor before taking other medicines with Adrenaline+lidocaine.

    Adrenaline+lidocaine causes drowsiness and vision disturbances. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.

    A person of age 65 or older should use Adrenaline+lidocaine with caution, as directed by the doctor as the chances of occurrence of side effects increase in older people.

    Adrenaline+lidocaine should be used with caution in patients suffering from heart rhythm disorders as it may increase the risk of severe adverse effects. Therefore, inform your doctor if you have any heart problems before taking Adrenaline+lidocaine so that the dose may be adjusted appropriately or an alternate medicine may be prescribed.

    Available Medicines for

    Lidocaine+adrenaline

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