Aceclofenac+rabeprazole
About Aceclofenac+rabeprazole
Aceclofenac+rabeprazole is a combination medication primarily used to reduce and relieve pain and inflammation (swelling) associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Aceclofenac+rabeprazole may also be indicated in the treatment of pain associated with post-traumatic and post-operative cases.
Aceclofenac+rabeprazole combines two drugs: Aceclofenac (painkiller) and Rabeprazole (antacid). Aceclofenac works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins. By blocking the effect of COX enzymes, lesser prostaglandins are produced. This helps reduce mild to moderate pain and inflammation at the injured or damaged site. Aceclofenac has been reported to cause gastric discomfort and acidity. Hence, it is combined with Rabeprazole, a medicine belonging to a group of proton pump inhibitors that reduce the amount of acid the stomach makes, thus preventing damage to the stomach. Thus, the combination helps alleviate pain with minimal gastric irritation caused due to Aceclofenac alone.
Take Aceclofenac+rabeprazole as prescribed by your doctor. You are advised to take Aceclofenac+rabeprazole for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience indigestion, stomach pain, constipation, dizziness, nausea and diarrhoea. Most of these side effects of Aceclofenac+rabeprazole do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Before taking the Aceclofenac+rabeprazole, let your doctor know about all your allergic or hypersensitivity reactions to medicines or food. Inform your doctor if you are suffering from kidney, liver, or heart disease. Aceclofenac+rabeprazole may cause dizziness, so avoid driving or operating machinery unless you are alert. Aceclofenac+rabeprazole is not recommended for use during pregnancy, breastfeeding and in children. Avoid consuming alcohol along with Aceclofenac+rabeprazole as it could lead to increased dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects.
Uses of Aceclofenac+rabeprazole
Medicinal Benefits
Aceclofenac+rabeprazole is a combination of two drugs: Aceclofenac (painkiller) and Rabeprazole (antacid). Aceclofenac belongs to the class of non-steroidal anti-inflammatory drugs (pain killers) that block the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). Prostaglandins play an important role in controlling pain and inflammation. By blocking the effect of COX enzymes, lesser PGs are produced. Thereby, it helps relieve pain and swelling associated with different types of arthritis, such as osteoarthritis, rheumatoid arthritis and ankylosing spondylitis (pain and stiffness in the backbone). On the other hand, Rabeprazole belongs to proton pump inhibitors (PPIs) that help reduce the excess amount of stomach acid and bile produced. Aceclofenac has been reported to cause gastric discomfort and acidity. Hence, it is combined with Rabeprazole, a medicine that reduces the amount of acid made by the stomach, thus preventing damage to the stomach. Thus, the combination is superior as it helps alleviate pain with minimal gastric irritation caused due to Aceclofenac alone. Aceclofenac+rabeprazole is also used to relieve toothache, lower back, ear, and throat pain.
Directions for Use
Storage
Side Effects of Aceclofenac+rabeprazole
- Indigestion
- Stomach pain
- Constipation
- Dizziness
- Nausea
- Diarrhoea
Patients Concern
Disease/Condition Glossary
Osteoarthritis: Osteoarthritis is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation and tenderness. The main reason for osteoarthritis is age; the older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear out as a person ages. Other reasons include past injuries such as torn cartilage, dislocated joints and ligaments.
Rheumatoid arthritis: Rheumatoid arthritis is an auto-immune disease (the body's immune system attacks its tissue) which leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function.
Ankylosing spondylitis: Ankylosing spondylitis causes pain and stiffness in the spine. The pain usually starts in the lower back and can spread to the neck, damaged joints or other parts of the body. Symptoms of ankylosing spondylitis include decreased flexibility which usually leads to hunched-forward posture, pain and back and joints.
FAQs
Aceclofenac+rabeprazole contains Aceclofenac and Rabeprazole. Aceclofenac is a pain killer called NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) which works by blocking the effect of chemical messengers (prostaglandin), thereby helping in reducing pain, and inflammation. Rabeprazole works by blocking the action of an enzyme called a proton pump, which is responsible for the production of stomach acid. Thus, the combination used for pain relief, decrease stiffness in joints and reduces the release of excess stomach acid caused by aceclofenac.
Aceclofenac+rabeprazole is not recommended for asthma patients as it may worsen the condition. Therefore, please inform your doctor if you have asthma or a history of asthma due to the use of aspirin or any other non-steroidal drugs.
You are not recommended to take Aceclofenac+rabeprazole with warfarin as co-administration of these two medicines may increase the risk of bleeding more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.
Aceclofenac in Aceclofenac+rabeprazole may increase the risk of heart problems such as heart attack, especially when used in high doses or for prolonged duration and in patients who are smokers, have high blood pressure, diabetes or high cholesterol. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking Aceclofenac+rabeprazole. However, taking Aceclofenac+rabeprazole in the dose and for the duration, as prescribed by your doctor, is recommended.
Aceclofenac+rabeprazole may impair fertility in females and make it more difficult to conceive. Therefore, if you are pregnant, planning for pregnancy or have difficulties conceiving, please consult your doctor before taking Aceclofenac+rabeprazole.
Do not take Aceclofenac+rabeprazole for longer durations as it might increase the risk of heart problems, stomach bleeding and might increase the risk of fractures of the hip, spine, and wrist. Do not exceed the dose and duration of treatment as prescribed by the doctor.
