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Reviewed By Sunny S , MBBS
Last Updated Aug 20, 2024 | 12:50 PM IST
Prescription drug
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Composition

DOMPERIDONE-10MG

Manufacturer/Marketer

Int-Intas Laboratories Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About DOMEL MT TABLET

DOMEL MT TABLET belongs to a class of medications known as 'dopamine antagonist' used to treat nausea (feeling sick) and vomit (being sick) in adults and adolescents 12 years or older. Besides this, it also helps in the treatment of indigestion. Nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying).

DOMEL MT TABLET contains domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.

Take DOMEL MT TABLET as prescribed by your doctor. Symptoms of nausea and vomiting may usually resolve within 3-4 days after taking DOMEL MT TABLET. However, if it does not resolve even after this, stop taking this medicine and contact the doctor. Do not take DOMEL MT TABLET for longer than seven days. The most common side effect of DOMEL MT TABLET is dry mouth. This side effect is temporary and may resolve after some time; however, if this side persists, contact the doctor.

Do not consume DOMEL MT TABLET if you are hypersensitive to any components present in DOMEL MT TABLET. Before taking the DOMEL MT TABLET, inform your doctor if you suffer from liver or kidney problems. Prolonged intake of DOMEL MT TABLET may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be more likely in the elderly (those over 60 years old) or taking doses higher than 30 mg daily. DOMEL MT TABLET is not usually recommended in pregnancy and breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine. Adolescents (children from 12-18 years of age) who weigh less than 35 kg should not be given the DOMEL MT TABLET.

Uses of DOMEL MT TABLET

Nausea, Vomiting.

Medicinal Benefits

DOMEL MT TABLET contains domperidone, a dopamine antagonist that helps by blocking certain vomiting-inducing receptors in the brain. DOMEL MT TABLET also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and decreases gastric emptying time. Domperidone is occasionally used to boost milk production. If you're experiencing difficulty nursing, your doctor may prescribe it if nothing else has helped.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.Oral Suspension/Syrup/Oral drops: Shake the bottle well before use. Check the label for directions and take DOMEL MT TABLET in doses as prescribed by your doctor with the help of a measuring cup/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of DOMEL MT TABLET

  • Dry mouth
  • Headache

Drug Warnings

Do not consume DOMEL MT TABLET if you are allergic to any components present in DOMEL MT TABLET. Before taking the DOMEL MT TABLET, contact your doctor if you suffer from liver or kidney problems (kidney function impairment or failure). Prolonged intake of DOMEL MT TABLET may be associated with an increased risk of heart rhythm disorder (arrhythmia) and cardiac arrest (heart attack). This risk may be more likely in the elderly (those over 60 years old) or taking doses higher than 30 mg daily. Tell your doctor if you are using anti-fungal medicines and/or if you have heart problems or AIDS/HIV. If you experience heart rhythm disorders like palpitations, trouble breathing, or loss of consciousness after taking the DOMEL MT TABLET, immediately contact your doctor. Domperidone is not usually recommended in pregnancy and breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine. Adolescents (children from 12-18 years of age) who weigh less than 35 kg should not be given the DOMEL MT TABLET.

Drug Interactions

Drug-Drug Interactions: DOMEL MT TABLET may interact with medicines used to treat heart problems or high blood pressure (e.g. amiodarone, dronedarone, quinidine, disopyramide, dofetilide, sotalol, diltiazem, verapamil), depression (e.g. citalopram, escitalopram),  anti-cancer agents (e.g. toremifene, vandetanib, vincamine), bacterial infections (e.g. specifically erythromycin, clarithromycin, telithromycin, moxifloxacin, pentamidine), gastrointestinal disorders (e.g. cisapride, dolasetron, prucalopride), antimalarial (e.g. halofantrine), neuro related medicines (e.g. haloperidol, pimozide, sertindole), antifungal (e.g. ketoconazole, fluconazole, voriconazole), gastrointestinal drugs (e.g. cisapride, dolasetron, prucalopride) and anti HIV drugs.

Drug-Food Interactions: DOMEL MT TABLET may interact with grapefruit juice, alcohol, and tobacco. This may affect the efficacy of DOMEL MT TABLET. So, a DOMEL MT TABLET should not be taken along with them.

Drug-Disease Interactions: Caution should be exercised while using DOMEL MT TABLET in patients with heart, kidney, liver disease, brain tumours, history of gastrointestinal bleeding, or any problem involving the bowels.

Drug-Drug Interactions Checker List

  • AMIODARONE
  • MOXIFLOXACIN
  • ERYTHROMYCIN
  • DILTIAZEM
  • SOTALOL
  • ESCITALOPRAM
  • VERAPAMIL

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy low-fat diet, especially in small portions, as it will be easy to digest. Avoid eating over-sweet food and include more salty food, especially if you have been vomiting.
  • Also, if you like vomiting at a specific time, avoid eating your favourite food at that particular time, as your taste for that food may get turned off. 
  • Include more cool beverages in your food like clear soups, flavoured gelatin, and carbonated beverages. And also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas or acidity.
  • Drink after or any other liquid at least 30 minutes after eating food. After eating food, lie down for at least after 2 hours.
  • If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else cook food or use prepared food from the freezer.
  • Avoid caffeine-containing beverages (coffee, tea), spicy/deep-fried/processed foods, carbonated drinks, and acidic foods like citrus fruits/vegetables (tomatoes).

Disease/Condition Glossary

Nausea is a feeling of stomach uneasiness that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. In short, nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). A receptor in our brain known as the chemoreceptor zone (CTZ) controls vomiting.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - DOM0019

FAQs

DOMEL MT TABLET contains domperidone, which prevents nausea and vomiting symptoms by blocking certain receptors (like dopamine and serotonin) that stimulate the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. It also acts as a prokinetic agent that increases the upper gastrointestinal tract's motility and helps decrease stomach emptying time.
If you are intolerant to sugars, please inform your doctor before starting DOMEL MT TABLET as it contains lactose. So, to avoid any unpleasant side effects, do as your doctor advises.
Yes, DOMEL MT TABLET can cause dry mouth. In case you feel excessively thirsty, please increase your fluid intake and do frequent mouth rinses.
If you miss a dose, take your medicine as soon as you remember. If it is almost time for your next dose, wait until that is due and continue as usual. Do not take a double dose to make up for a forgotten dose.
Domperidone should be used for the shortest time. It is commonly taken for up to a week. Domperidone can produce irregular heartbeats if taken for an extended time or at a high dose.
No, it is a prescribed medication; it should be used only if specified by the doctor.

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Alcohol

Caution

Drinking alcohol with DOMEL MT TABLET may cause sleepiness, or an irregular heartbeat.

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Pregnancy

Unsafe

DOMEL MT TABLET is not usually recommended in pregnancy.

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Breast Feeding

Caution

DOMEL MT TABLET is not usually recommended when breastfeeding. But in some cases, domperidone is used to increase milk supply. However, it should be used only during breastfeeding if your physician considers this necessary. Ask your doctor for advice before taking this medicine.

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Driving

Safe if prescribed

DOMEL MT TABLET has no effect on your ability to drive or operate machinery.

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Liver

Caution

DOMEL MT TABLET should be taken with precaution in patients with liver disease. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.

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Kidney

Caution

DOMEL MT TABLET should be taken with caution in patients with kidney problems. Your doctor will adjust your dose depending upon the condition of your disease.

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Children

Caution

DOMEL MT TABLET should not be given to adolescents younger than 12 years of age or are less than 35 kg in weight.