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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sureshvarma D , MPharma
Last Updated Aug 20, 2024 | 1:08 PM IST
Prescription drug
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Manufacturer/Marketer

Zydus Healthcare Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Aldonil Plus Tablet 10's

Aldonil Plus Tablet 10's is a combination medicine indicated for the management of diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It primarily damages the nerves in the legs and feet. Diabetic neuropathic pain is common in patients with type 1 and type 2 diabetes.
 
Aldonil Plus Tablet 10's contains Epalrestat and Methylcobalamin. Epalrestat works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol, thereby preventing the accumulation of sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients suffering from diabetes which leads to nerve pain. Methylcobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Together, Aldonil Plus Tablet 10's helps in treating diabetic neuropathy.
 
You are advised to take Aldonil Plus Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as nausea, vomiting, diarrhoea, dizziness, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Aldonil Plus Tablet 10's may cause drowsiness and dizziness, so drive only if you are alert. Aldonil Plus Tablet 10's is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Aldonil Plus Tablet 10's as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side effects/interactions.

Uses of Aldonil Plus Tablet 10's

Diabetic neuropathy (diabetic nerve pain)

Medicinal Benefits

Aldonil Plus Tablet 10's is a combination of two drugs, namely: Epalrestat and Methylcobalamin. Aldonil Plus Tablet 10's is indicated for the management of diabetic neuropathy. Epalrestat works by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. This prevents the accumulation of sorbitol. Accumulation of sorbitol occurs due to hyperglycaemia in patients suffering from diabetes which leads to nerve pain. Methylcobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Together, Aldonil Plus Tablet 10's helps in treating diabetic neuropathy.

Directions for Use

Swallow Aldonil Plus Tablet 10's as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Aldonil Plus Tablet 10's

  • Dizziness
  • Nausea
  • Vomiting
  • Headache
  • Diarrhoea

Drug Warnings

Do not take Aldonil Plus Tablet 10's if you are allergic to any of its components. Inform your doctor if you have liver or kidney problems. Consult your doctor if you are pregnant or breastfeeding. Aldonil Plus Tablet 10's may cause drowsiness and dizziness, so drive only if you are alert. Aldonil Plus Tablet 10's is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol with Aldonil Plus Tablet 10's as it could lead to increased drowsiness and sleepiness. 

Drug Interactions

Drug-Drug Interactions: Aldonil Plus Tablet 10's may interact with antibiotic (chloramphenicol) and anti-diabetic (metformin).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have severe liver or kidney dysfunction.

Drug-Drug Interactions Checker List

  • CHLORAMPHENICOL
  • METFORMIN

Habit Forming

No

Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain. 
  • Rest well, get plenty of sleep.
  • Try taking a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Disease/Condition Glossary

Diabetic neuropathy: Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in the legs and feet. Diabetic neuropathic pain is common in patients with type1 and type2 diabetes, which usually develops slowly. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty with coordination when walking, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).

Country of origin

India

Manufacturer/Marketer address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Other Info - ALD0072

FAQs

Aldonil Plus Tablet 10's is a combination of two drugs, namely: Epalrestat and Methylcobalamin. Epalrestat prevents the accumulation of sorbitol by inhibiting the aldose reductase enzyme, which catalyses the conversion of glucose to sorbitol. Methylcobalamin helps in the rejuvenation and protection of damaged nerve cells by producing a substance called myelin. Together, Aldonil Plus Tablet 10's helps in treating diabetic neuropathy.
Diarrhoea could be a side-effect of Aldonil Plus Tablet 10's. Drink plenty of fluids to prevent dehydration and consume non-spicy meals if you experience diarrhoea. Consult your doctor if you have severe diarrhoea.
Inform your doctor if you notice any cut/sore on your feet that is not healing or if you have a tingling/burning sensation in your feet/arms causing a hamper to the daily routine. If you experience trouble in sexual function, digestion, or urination, please consult a doctor. Examine your feet daily for lesions and wear proper footwear to prevent diabetic neuropathy.
Do not discontinue Aldonil Plus Tablet 10's without consulting your doctor. To treat your condition effectually, continue taking Aldonil Plus Tablet 10's for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Aldonil Plus Tablet 10's.
Aldonil Plus Tablet 10's may cause peripheral oedema. Peripheral oedema is the swelling of the hands and lower legs. Avoid sitting or standing for too long. Raise your legs by putting a pillow under the legs while lying down.
Aldonil Plus Tablet 10's does not help in controlling diabetes. Aldonil Plus Tablet 10's is indicated to treat neuropathic pain. It is recommended to adhere to your diabetic medicines to keep your blood sugar levels at normal.

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Alcohol

Caution

Avoid consumption of alcohol while taking Aldonil Plus Tablet 10's as it may cause increased dizziness.

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Pregnancy

Caution

Please consult your doctor if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Aldonil Plus Tablet 10's; your doctor will decide whether Aldonil Plus Tablet 10's can be taken by breastfeeding mothers or not.

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Driving

Caution

Aldonil Plus Tablet 10's may cause dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Limited information is available regarding the use of Aldonil Plus Tablet 10's in patients with liver disease. Please consult your doctor.

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Kidney

Caution

Limited information is available regarding the use of Aldonil Plus Tablet 10's in patients with kidney impairment. Please consult your doctor.

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Children

Caution

Aldonil Plus Tablet 10's should not be given to children as safety and efficacy have not been established.

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