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48 Hrs returnable
COD available

Online payment accepted

Prescription drug

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DENOSUMAB-60MG
PARENTERAL
Not Returnable
Apr-24
Prescription drug
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Country of origin

India
Other Info - DEN0349

FAQs

Denoclast 60 mg Injection binds to a protein on RANK ligand on osteoclast (cells that cause bone breakdown) and inhibits their formation, functioning and survival. Thereby decreases bone breakdown, increases bone density, and strengthens the bone. Denoclast 60 mg Injection makes the bones stronger and less likely to break.
Osteonecrosis of the jaw (bone damage in the jaw) might be a side-effect of Denoclast 60 mg Injection. The risk increases in people taking Denoclast 60 mg Injection for longer durations. It might also occur upon discontinuation of the treatment. Maintain good dental hygiene and receive regular dental check-ups whilst on treatment with Denoclast 60 mg Injection. Inform your doctor if you have dental problems, gum disease, planned tooth extractions, cancer, if you smoke, or are taking bisphosphonates or corticosteroids.
Breakdown of bones releases calcium and causes hypercalcemia (high calcium levels in the blood). Denoclast 60 mg Injection helps treat high calcium levels by decreasing bone breakdown.
Unusual thigh bone fractures might occur whilst on treatment with Denoclast 60 mg Injection. Consult your doctor if you experience new or unusual pain in the thigh, hip, or groin.
Denoclast 60 mg Injection treats giant cell tumour of bone (GCTB) by blocking certain receptors in the tumour cells, thereby slows the tumour growth. Giant cell tumour of the bone is a non-cancerous tumour that typically grows at the ends of long bones.
Denoclast 60 mg Injection might cause skin infections. Consult your doctor immediately if you notice symptoms such as swollen skin, redness, cellulitis (hot and tender skin), commonly in the lower leg with feverish symptoms.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

It is not known if alcohol interacts with Denoclast 60 mg Injection, so please consult a doctor.

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Pregnancy

Unsafe

Denoclast 60 mg Injection is not recommended during pregnancy as it might cause foetal harm. If you are a woman of child-bearing potential, use effective contraception during the treatment with Denoclast 60 mg Injection and for 5 months after discontinuation. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.

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Breast Feeding

Caution

Consult your doctor if you are breastfeeding; your doctor will decide if breastfeeding mothers can take Denoclast 60 mg Injection or not.

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Driving

Safe if prescribed

Denoclast 60 mg Injection generally does not affect your ability to drive. However, drive or operate machinery only if you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Denoclast 60 mg Injection is not recommended for children below 18 years as safety and effectiveness were not established.

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Keep Refrigerated. Do not freeze.Prepaid payment required.

About Denoclast 60 mg Injection

Denoclast 60 mg Injection belongs to a group of medicines called RANK ligand inhibitors used to treat osteoporosis in postmenopausal women and men who have an increased risk of fracture. Denoclast 60 mg Injection is also used to treat bone loss due to reduced testosterone level caused by surgery, due to the treatment with medicines such as glucocorticoids and in patients with prostate cancer. Denoclast 60 mg Injection may also be used to reduce the risk of fractures in people with multiple myeloma, giant cell tumour of the bone, and to treat high calcium levels caused due to cancer.
 
Denoclast 60 mg Injection contains ‘denosumab’, which works by blocking a receptor in the body that causes bone loss, thereby treats bone loss. Denoclast 60 mg Injection treats giant cell tumour of bone (GCTB) by blocking certain receptors in the tumour cells, thereby slowing the tumour growth. Denoclast 60 mg Injection helps treat high calcium levels by decreasing bone breakdown as a breakdown of the bones releases calcium. Denoclast 60 mg Injection makes the bones stronger and less likely to break.
 
Denoclast 60 mg Injection will be administered by a healthcare professional; do not self-administer. In some cases, you may experience common side-effects such as bone/joint/muscle pain, arm/leg pain, abdominal discomfort, constipation, and painful/frequent urination. You are advised to talk to your doctor if the side effects persist or worsen.
 
Denoclast 60 mg Injection might cause osteonecrosis of the jaw; therefore, maintain good dental hygiene and receive regular dental check-ups whilst on treatment with Denoclast 60 mg Injection. Avoid taking Denoclast 60 mg Injection if you are pregnant. Consult your doctor before taking Denoclast 60 mg Injection if you are breastfeeding. Denoclast 60 mg Injection is not recommended for children below 18 years as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any interactions.

Uses of Denoclast 60 mg Injection

Osteoporosis, bone loss, giant cell tumour of the bone, high calcium levels.

Medicinal Benefits Mweb

Medicinal Benefits

Denoclast 60 mg Injection belongs to a group of medicines called RANK ligand inhibitors used to treat osteoporosis in postmenopausal women and men who have an increased risk of fracture. Denoclast 60 mg Injection is also used to treat bone loss due to reduced hormone levels caused by surgery or due to treatment with medicines in patients with prostate cancer. It is also used to treat bone loss occurring due to long-term treatment with glucocorticoids in patients who are at an increased risk of fractures. Denoclast 60 mg Injection may also be used to reduce the risk of fractures in people with multiple myeloma, giant cell tumours of the bone and to treat high calcium levels caused due to cancer. Denoclast 60 mg Injection binds to a protein on RANK ligand on osteoclast (cells that cause bone breakdown) and inhibits their formation, functioning and survival. Thereby decreases bone breakdown, increases bone density, and strengthens the bone. Denoclast 60 mg Injection treats giant cell tumour of bone (GCTB) by blocking certain receptors in the tumour cells, thereby slows the tumour growth. Denoclast 60 mg Injection helps treat high calcium levels by decreasing bone breakdown as the breakdown of the bones releases calcium. Denoclast 60 mg Injection makes the bones stronger and less likely to break.

Directions for Use

Denoclast 60 mg Injection will be administered by a healthcare professional; do not self-administer.

Side Effects of Denoclast 60 mg Injection

  • Bone/joint/muscle pain
  • Pain in extremities (arm/leg pain)
  • Abdominal discomfort
  • Constipation
  • Painful/frequent urination
  • Upper respiratory tract infection
  • Rash
  • Eczema
  • Hair loss

Drug Warnings

Do not take Denoclast 60 mg Injection if you are allergic to any of its components; if you have hypocalcaemia (low levels of calcium in the blood). Inform your doctor if you have low levels of calcium, kidney dysfunction, liver problems, poor dental health, gum problems, weak immune system, hypoparathyroidism (decreased function of the parathyroid gland), malabsorption, latex allergy, undergone thyroid surgery, planned dental procedure, if you are taking glucocorticoids, or cannot take calcium and vitamin D supplements. Avoid taking Denoclast 60 mg Injection if you are pregnant. Consult your doctor if you are breastfeeding. Denoclast 60 mg Injection is not recommended for children below 18 years as safety and effectiveness have not been established.

Drug-Drug Interactions

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DenosumabCladribine
Severe
DenosumabEtelcalcetide
Severe

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Drug Interactions Checker List

  • PALBOCICLIB

Habit Forming

No

Special Advise

  • If you are a woman of child-bearing potential, use effective contraception during the treatment with Denoclast 60 mg Injection and for 5 months after discontinuation. 
  • Your doctor might prescribe calcium and vitamin D supplements whilst on treatment with Denoclast 60 mg Injection.

Diet & Lifestyle Advise

  • Include dairy products like milk, yoghurt, cheese, or milk-based custard in your diet.
  • Eat daily a serving of broccoli, cabbage, bok choy (Chinese white cabbage), spinach, and other green leafy vegetables.
  • Snack on calcium-rich nuts like Brazil nuts or almonds.
  • Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
  • Avoid or reduce the intake of caffeine, soft drinks, and alcohol as they may inhibit calcium absorption.
  • Replace the meat with tofu or tempeh for extra calcium in your food.

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