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  1. Home
  2. Medicine

  3. Casodex 150mg Tablet 14's

Prescription drug
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Composition :

BICALUTAMIDE-50MG

Manufacturer/Marketer :

Astra Zeneca Pharma India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

Therapeutic Class

ANTINEOPLASTIC

Country of origin

India

Manufacturer/Marketer address

Corporate & Registered Office, Block N1, 12Th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore
Other Info - CAS0015

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:34 AM IST

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Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Interaction of Casodex 150mg Tablet with alcohol is unknown. Please consult a doctor before consuming alcohol while using Casodex 150mg Tablet .

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Pregnancy

Unsafe

Casodex 150mg Tablet is contraindicated in pregnant women as it is not approved for use in women. Please consult a doctor if you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Casodex 150mg Tablet is contraindicated in breastfeeding women as it is not approved for use in women. Please consult a doctor if you are breastfeeding.

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Driving

Caution

Casodex 150mg Tablet may cause drowsiness in some people. Therefore, avoid driving if you are drowsy after taking Casodex 150mg Tablet .

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Liver

Caution

Take Casodex 150mg Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Safe if prescribed

Casodex 150mg Tablet is safe to use in patients with kidney problems if prescribed by a doctor.

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Children

Unsafe

Casodex 150mg Tablet is not recommended for children as the safety and effectiveness were not established.

Product Substitutes

Reference

  1. https://www.medicines.org.uk/emc/files/pil.2052.pdf
  2. https://www.drugs.com/cdi/bicalutamide.html

About Casodex 150mg Tablet

Casodex 150mg Tablet belongs to the class of anticancer drugs called non-steroidal anti-androgens used to treat prostate cancer. Prostate cancer is prostate gland cancer (a small gland under the bladder that produces semen) found only in men. The symptoms include difficulty in urination, pain, numbness, or sexual problems.

Casodex 150mg Tablet contains Bicalutamide which works by inhibiting the effects of androgens (male hormones) such as testosterone that increase the growth of prostate cancer cells. Casodex 150mg Tablet prevents testosterone from binding to androgen receptors on the prostate cancer cells and starves cancer cells of testosterone. Thereby, it prevents the growth of prostate cancer cells and eventually shrinks the prostate tumor.

Take Casodex 150mg Tablet with or without food as advised by your doctor and swallow whole with a glass of water. Do not crush, chew or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience weakness, skin rash, swelling and tenderness of the breast, nausea, dry skin, weight gain, hair loss, hot flushes (sudden feeling of warmth), anemia (lack of blood), reduces sex drive, constipation, depression, indigestion or dizziness. Most of these side effects of Casodex 150mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Casodex 150mg Tablet or any other medicines, please tell your doctor. Casodex 150mg Tablet is not recommended for women and children. Please consult a doctor if you are pregnant or breastfeeding before taking Casodex 150mg Tablet . Please consult a doctor if you want to father a child before taking Casodex 150mg Tablet as it may impair fertility in men. Avoid taking Casodex 150mg Tablet with cisapride, astemizole, or terfenadine. Avoid direct exposure to excessive UV light or sunlight and wear protective clothing while going out in the sun as Casodex 150mg Tablet may increase sunburn risk. If you have diabetes, liver, or heart problems, inform your doctor before taking Casodex 150mg Tablet .

Uses of Casodex 150mg Tablet

Prostate cancer

Medicinal Benefits Mweb

Medicinal Benefits

Casodex 150mg Tablet contains Bicalutamide, an anticancer drug used in the treatment of prostate cancer. Casodex 150mg Tablet works by inhibiting the effects of androgens (male hormones) such as testosterone that increase the growth of prostate cancer cells. Casodex 150mg Tablet prevents testosterone from binding to androgen receptors on the prostate cancer cells and starves cancer cells of testosterone. Thereby, it prevents the growth of prostate cancer cells and eventually shrinks the prostate tumor. Also, Casodex 150mg Tablet relieves difficulty in urination. Casodex 150mg Tablet can be used in combination with radiation therapy to treat prostate cancer where cancer has spread from the prostate gland to the surrounding tissues.

Directions for Use

Take Casodex 150mg Tablet with or without food as prescribed by your doctor and swallow whole with a glass of water. Do not crush, chew or break it.

Side Effects of Casodex 150mg Tablet

  • Weakness
  • Skin rash
  • Swelling and tenderness of breast
  • Nausea
  • Dry skin
  • Weight gain
  • Hair loss
  • Hot flushes (sudden feeling of warmth)
  • Anaemia (lack of blood)
  • Reduced sex drive
  • Constipation
  • Depression
  • Indigestion
  • Dizziness

Drug Warnings

If you are allergic to Casodex 150mg Tablet or any other medicines, please tell your doctor. Casodex 150mg Tablet is not recommended for women and children. Please consult a doctor if you are pregnant or breastfeeding before taking Casodex 150mg Tablet . You and your partner recommend using effective birth control measures while taking Casodex 150mg Tablet and for 130 days after discontinuing Casodex 150mg Tablet . Please consult a doctor if you want to father a child before taking Casodex 150mg Tablet as it may impair fertility in men. You are advised to quit smoking as it may increase the risk of prostate cancer. Avoid taking Casodex 150mg Tablet with cisapride, astemizole, or terfenadine. Regular tests are recommended to monitor liver function and if there is any severe disturbance in liver functioning, avoid taking Casodex 150mg Tablet . Avoid direct exposure to excessive UV light or sunlight and wear protective clothing while going out in the sun as Casodex 150mg Tablet may increase sunburn risk. If you have diabetes, liver, or heart problems, inform your doctor before taking Casodex 150mg Tablet .

Drug-Drug Interactions

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BicalutamideSaquinavir
Critical
BicalutamideZiprasidone
Critical

Drug-Drug Interactions

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BicalutamideSaquinavir
Critical
How does the drug interact with Casodex 150mg Tablet:
When Casodex 150mg Tablet is taken with Saquinavir, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Casodex 150mg Tablet with Saquinavir is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamideZiprasidone
Critical
How does the drug interact with Casodex 150mg Tablet:
Taking Casodex 150mg Tablet and Ziprasidone can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Casodex 150mg Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
BicalutamideThioridazine
Critical
How does the drug interact with Casodex 150mg Tablet:
Taking Casodex 150mg Tablet with Thioridazine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Casodex 150mg Tablet with Thioridazine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamidePimozide
Critical
How does the drug interact with Casodex 150mg Tablet:
When Casodex 150mg Tablet is taken with Pimozide, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Casodex 150mg Tablet with Pimozide is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamideDronedarone
Critical
How does the drug interact with Casodex 150mg Tablet:
When Casodex 150mg Tablet is taken with Dronedarone, can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Casodex 150mg Tablet with Dronedarone is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamideMesoridazine
Critical
How does the drug interact with Casodex 150mg Tablet:
Taking Casodex 150mg Tablet with Mesoridazine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Casodex 150mg Tablet with Mesoridazine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamideHalofantrine
Critical
How does the drug interact with Casodex 150mg Tablet:
Taking Casodex 150mg Tablet with Halofantrine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Casodex 150mg Tablet with Halofantrine is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
BicalutamideOlaparib
Severe
How does the drug interact with Casodex 150mg Tablet:
When Casodex 150mg Tablet is taken with Olaparib, it can increase the blood levels and effects of Olaparib.

How to manage the interaction:
Although there is a possible interaction between Casodex 150mg Tablet and Olaparib, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
BicalutamideDofetilide
Severe
How does the drug interact with Casodex 150mg Tablet:
Co-administration of Casodex 150mg Tablet and Dofetilide together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Casodex 150mg Tablet and Dofetilide together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
BicalutamideToremifene
Severe
How does the drug interact with Casodex 150mg Tablet:
Co-administration of Casodex 150mg Tablet and Toremifene together can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Casodex 150mg Tablet and Toremifene together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CISAPRIDE
  • ASTEMIZOLE
  • TERFENADINE
  • PROCAINAMIDE
  • AMIODARONE
  • SOTALOL
  • QUINIDINE
  • MOXIFLOXACIN
  • METHADONE
  • WARFARIN
  • CICLOSPORIN
  • CIMETIDINE
  • KETOCONAZOLE

Habit Forming

No

Special Advise

Regular blood tests are recommended to monitor changes in blood and liver functioning while taking Casodex 150mg Tablet .

Diet & Lifestyle Advise

  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk and dairy products as they may increase prostate cancer risk.
  • Exercise regularly to lose weight as obesity is also considered as a risk factor for prostate cancer.
  • Quit smoking to reduce the risk of prostate cancer.

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