Caluran 50 mg Tablet 10's belongs to the class of anticancer drugs called non-steroidal anti-androgens used to treat prostate cancer. Prostate cancer is prostate gland cancer (a small gland under the bladder that produces semen) found only in men. The symptoms include difficulty in urination, pain, numbness, or sexual problems.

Caluran 50 mg Tablet 10's contains Bicalutamide which works by inhibiting the effects of androgens (male hormones) such as testosterone that increase the growth of prostate cancer cells. Caluran 50 mg Tablet 10's prevents testosterone from binding to androgen receptors on the prostate cancer cells and starves cancer cells of testosterone. Thereby, it prevents the growth of prostate cancer cells and eventually shrinks the prostate tumor.

Take Caluran 50 mg Tablet 10's with or without food as advised by your doctor and swallow whole with a glass of water. Do not crush, chew or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience weakness, skin rash, swelling and tenderness of the breast, nausea, dry skin, weight gain, hair loss, hot flushes (sudden feeling of warmth), anemia (lack of blood), reduces sex drive, constipation, depression, indigestion or dizziness. Most of these side effects of Caluran 50 mg Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Caluran 50 mg Tablet 10's or any other medicines, please tell your doctor. Caluran 50 mg Tablet 10's is not recommended for women and children. Please consult a doctor if you are pregnant or breastfeeding before taking Caluran 50 mg Tablet 10's. Please consult a doctor if you want to father a child before taking Caluran 50 mg Tablet 10's as it may impair fertility in men. Avoid taking Caluran 50 mg Tablet 10's with cisapride, astemizole, or terfenadine. Avoid direct exposure to excessive UV light or sunlight and wear protective clothing while going out in the sun as Caluran 50 mg Tablet 10's may increase sunburn risk. If you have diabetes, liver, or heart problems, inform your doctor before taking Caluran 50 mg Tablet 10's.

Caluran 50 mg Tablet 10's contains Bicalutamide, an anticancer drug used in the treatment of prostate cancer. Caluran 50 mg Tablet 10's works by inhibiting the effects of androgens (male hormones) such as testosterone that increase the growth of prostate cancer cells. Caluran 50 mg Tablet 10's prevents testosterone from binding to androgen receptors on the prostate cancer cells and starves cancer cells of testosterone. Thereby, it prevents the growth of prostate cancer cells and eventually shrinks the prostate tumor. Also, Caluran 50 mg Tablet 10's relieves difficulty in urination. Caluran 50 mg Tablet 10's can be used in combination with radiation therapy to treat prostate cancer where cancer has spread from the prostate gland to the surrounding tissues.

• Weakness
• Skin rash
• Swelling and tenderness of breast
• Nausea
• Dry skin
• Weight gain
• Hair loss
• Hot flushes (sudden feeling of warmth)
• Anaemia (lack of blood)
• Reduced sex drive
• Constipation
• Depression
• Indigestion
• Dizziness

If you are allergic to Caluran 50 mg Tablet 10's or any other medicines, please tell your doctor. Caluran 50 mg Tablet 10's is not recommended for women and children. Please consult a doctor if you are pregnant or breastfeeding before taking Caluran 50 mg Tablet 10's. You and your partner recommend using effective birth control measures while taking Caluran 50 mg Tablet 10's and for 130 days after discontinuing Caluran 50 mg Tablet 10's. Please consult a doctor if you want to father a child before taking Caluran 50 mg Tablet 10's as it may impair fertility in men. You are advised to quit smoking as it may increase the risk of prostate cancer. Avoid taking Caluran 50 mg Tablet 10's with cisapride, astemizole, or terfenadine. Regular tests are recommended to monitor liver function and if there is any severe disturbance in liver functioning, avoid taking Caluran 50 mg Tablet 10's. Avoid direct exposure to excessive UV light or sunlight and wear protective clothing while going out in the sun as Caluran 50 mg Tablet 10's may increase sunburn risk. If you have diabetes, liver, or heart problems, inform your doctor before taking Caluran 50 mg Tablet 10's.

Drug-Drug Interactions: Caluran 50 mg Tablet 10's may have interaction with medicine for stomach disorders (cisapride), anti-allergic drugs (astemizole, terfenadine), heart-related drugs (procainamide, amiodarone, sotalol, quinidine), antibiotic (moxifloxacin), opioid painkiller (methadone), blood thinner (warfarin), immunosuppressant (ciclosporin), antacid (cimetidine), antifungal (ketoconazole).

Drug-Food Interactions: Caluran 50 mg Tablet 10's may interact with grapefruit juice. Therefore, avoid intake of grapefruit juice with Caluran 50 mg Tablet 10's as it may increase concentrations of Caluran 50 mg Tablet 10's and cause more adverse effects.

Drug-Disease Interactions: If you have diabetes, liver or heart problems, inform your doctor before taking Caluran 50 mg Tablet 10's.

• CISAPRIDE
• ASTEMIZOLE
• TERFENADINE
• PROCAINAMIDE
• AMIODARONE
• SOTALOL
• QUINIDINE
• MOXIFLOXACIN
• METHADONE
• WARFARIN
• CICLOSPORIN
• CIMETIDINE
• KETOCONAZOLE

• Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
• Avoid grilled meat, red meat, saturated fat found in animal products, milk and dairy products as they may increase prostate cancer risk.
• Exercise regularly to lose weight as obesity is also considered as a risk factor for prostate cancer.
• Quit smoking to reduce the risk of prostate cancer.

Regular blood tests are recommended to monitor changes in blood and liver functioning while taking Caluran 50 mg Tablet 10's.

Prostate cancer: It is prostate gland cancer (a small gland under the bladder that produces semen) found only in men. The symptoms include difficulty in urination, pain, numbness, or sexual problems. It is the most common type of cancer in men. The cause of prostate cancer is unknown and may be caused due to exposure to certain chemicals or family history. There are certain factors that increase the risk of prostate cancer, such as a family history of prostate cancer, older age, obesity, or genetic changes.