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Written By Urvashi Bharti , MBBS
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Last Updated Aug 20, 2024 | 12:51 PM IST
Prescription drug
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Composition

FEBUXOSTAT-40MG

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Foxstat-40 Tablet 10's

Foxstat-40 Tablet 10's belongs to a class of anti-gout medications, also known as xanthine oxidase inhibitors, widely used to prevent severe gout attacks or flares. Gout is a chronic condition that occurs due to the deposition of uric acid crystals in the joints. It is characterized by intense pain and swelling at the affected joints. Foxstat-40 Tablet 10's prevents the sudden attacks of pain caused by severe gout and decreases pain, swelling, and inflammation.

Foxstat-40 Tablet 10's contains febuxostat. It works by inhibiting the enzyme xanthine oxidase (an enzyme that helps your body make uric acid), thereby reducing the level of uric acid in your body. Thus, it reduces the inflammation caused by uric acid crystals in affected joints, thereby reducing pain, swelling and inflammation. Foxstat-40 Tablet 10's is used to prevent gout attacks or flares.

Your doctor will advise you on how often you take off the Foxstat-40 Tablet 10's based on your medical condition. The common side effects of Foxstat-40 Tablet 10's nausea, rash, dizziness, diarrhoea, pain, rash, inaccurate liver function test results, gout flare-ups (intense joint pain that comes on suddenly, often in the middle of the night), localized swelling due to retention of fluids in tissues (oedema). Most of these side effects of Foxstat-40 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not stop taking a Foxstat-40 Tablet 10's of your own. Stopping it may worsen your condition and increase the risk of increased uric acid levels and future gout attacks. Inform your doctor if you have allergic to Foxstat-40 Tablet 10's or any other medicines, have a heart problem (Foxstat-40 Tablet 10's may cause heart problems that can lead to heart attack), or have kidney/liver disease. Some people experience more gout flare-ups when you start taking Foxstat-40 Tablet 10's. You should continue taking this drug even if gout flare-ups occur. Your doctor may give you combination therapy to prevent flare-ups when you start Foxstat-40 Tablet 10's. The safety and effectiveness of children under 18 years of age have not been established, so Foxstat-40 Tablet 10's should not be given to them. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Foxstat-40 Tablet 10's.

Uses of Foxstat-40 Tablet 10's

Treatment of severe gout, prevention of gout attacks

Medicinal Benefits

Foxstat-40 Tablet 10's is a class of medications called xanthine oxidase (enzyme that helps your body to make the uric acid) inhibitors. It works by inhibiting the enzyme xanthine oxidase, thereby reducing the level of uric acid that is made in your body. Thus, it reduces the inflammation caused by uric acid crystals in affected joints, thereby reducing pain, swelling and inflammation. Foxstat-40 Tablet 10's is used to prevent gout attacks or flares.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Foxstat-40 Tablet 10's

  • Nausea
  • Rash
  • Dizziness
  • Diarrhoea
  • Joint pain
  • Rash,
  • Inaccurate liver function test results
  • Gout flare-ups (intense joint pain that comes on suddenly, often in the middle of the night)
  • Localized swelling due to retention of fluids in tissues (oedema)

Drug Warnings

You should avoid taking Foxstat-40 Tablet 10's if you are allergic to Foxstat-40 Tablet 10's, or have heart-related problems, as it increases the risk of a heart attack. It should be used cautiously in patients with kidney problems and blood disorders. Caution is required before taking Foxstat-40 Tablet 10's if you are pregnant, planning to become pregnant, or already a breastfeeding mother. The safety and effectiveness of children under 18 years of age have not been established, so Foxstat-40 Tablet 10's should not be given to them.

Drug Interactions

Drug-Drug Interactions: Foxstat-40 Tablet 10's interacts with anticancer medications (mercaptopurine, methotrexate), immunosuppressant medications (azathioprine), antidiabetic medications (rosiglitazone), and antiasthma medications (theophylline).

Drug-Food Interactions: Intake of alcohol may increase the risk of side effects, so avoid taking alcohol with Foxstat-40 Tablet 10's. Limit the purine-rich diet.

Drug-Disease Interactions: Brief your doctor if you have a medical history of allergic reactions to medicines,  hyperuricemia (an abnormally high level of uric acid in the blood), heart diseases, liver or kidney diseases before taking Foxstat-40 Tablet 10's.

Drug-Drug Interactions Checker List

  • MERCAPTOPURINE
  • METHOTREXATE
  • AZATHIOPRINE
  • THEOPHYLLINE
  • ROSIGLITAZONE

Habit Forming

No

Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulfate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish can help in reducing inflammation in the tissue.
  • Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do low-impact aerobic movements like walking on a treadmill and swimming. You can also strengthen your muscles by lifting light weights.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short duration of time. Long-term immobility is harmful in conditions like arthritis. Use back support like a rolled-up towel to minimise pain at the back of your spine curve. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.
  • Avoid a high purine-rich diet, including organ meats (kidneys, liver, and sweetbreads) and oily fish (sardines, anchovies, and herring).
  • Limit meat in favour of plant-based proteins like beans and legumes.
  • Eat complex carbohydrates, such as whole-grain bread, fruits, and vegetables, rather than sugary sweets and refined carbohydrates like white bread.
  • Avoid drinking beer and alcoholic beverages and drink plenty of water or other nonalcoholic beverages.

Special Advise

  • Please consult your doctor and check your levels of uric acid two weeks after starting Foxstat-40 Tablet 10's. Your goal is a uric acid level in your blood that is less than 6 mg/dL.

Disease/Condition Glossary

Gout: Gout is a type of arthritis called 'gouty arthritis'. It is caused by a build-up of a naturally occurring chemical (uric acid) in your body (hyperuricemia). The excess uric acid deposit and crystallize in the joints leading to pain and inflammation. The general signs and symptoms of gout include sudden, severe attacks of pain, swelling, redness, and tenderness in the joints, mostly in the joint at the base of the big toe. Patients with gout may often experience acute attacks that result in sudden and severe pain, often waking you up in the middle of the night with the sensation that your big toe is on fire.

Country of origin

India

Manufacturer/Marketer address

20, Dr. E. Moses Road, Mahalaxmi, Mumbai - 400 011
Other Info - FOX0010

FAQs

Foxstat-40 Tablet 10's is a class of antigout drugs called xanthine oxidase inhibitors. It works by decreasing a high amount of uric acid to the normal level that is made in the body. Foxstat-40 Tablet 10's is used to prevent gout attacks but not to treat them once they occur.
No, Do not discontinue Foxstat-40 Tablet 10's without consulting your doctor. To treat your condition effectively, continue taking Foxstat-40 Tablet 10's for as long as prescribed. If you stop taking Foxstat-40 Tablet 10's, your uric acid levels will likely remain high and continue to cause gout symptoms.
Foxstat-40 Tablet 10's is not recommended if you have heart disease; taking Foxstat-40 Tablet 10's may cause serious heart problems, which can be life-threatening in some cases. So, please consult your doctor before taking the Foxstat-40 Tablet 10's.
Do not drive or operate machinery if you experience dizziness or drowsiness while using Foxstat-40 Tablet 10's.
The dose and duration of Foxstat-40 Tablet 10's depend upon your medical condition. It may take several months before Foxstat-40 Tablet 10's begins to prevent gout attacks. Do not stop taking Foxstat-40 Tablet 10's without the advice of your doctor even if you feel better.
It is best taken in the morning. You can take Foxstat-40 Tablet 10's with or without food. Keep taking Foxstat-40 Tablet 10's every day, to prevent gout attacks.

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Alcohol

Caution

You should avoid taking alcohol while taking Foxstat-40 Tablet 10's because alcohol may affect Foxstat-40 Tablet 10's effectiveness.

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Pregnancy

Caution

Foxstat-40 Tablet 10's should not be taken until prescribed. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Breast Feeding

Caution

There is limited data on how Foxstat-40 Tablet 10's affects breastfeeding. Please consult your doctor before starting Foxstat-40 Tablet 10's.

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Driving

Caution

Do not drive or operate machinery if you experience sleepiness, blurred vision and numbness or tingling sensation while using Foxstat-40 Tablet 10's. Seek medical attention if the symptoms persist longer.

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Liver

Caution

Let your doctor know if you have any history of liver disease or hepatic impairment. Your doctor will weigh the benefits and any potential risks before prescribing Foxstat-40 Tablet 10's.

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Kidney

Caution

Foxstat-40 Tablet 10's should be used with caution in patients with renal impairment. The doctor may adjust the dose depending on your condition.

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Children

Caution

Foxstat-40 Tablet 10's is not recommended for children below the age of 18 years. The safety and efficacy of Foxstat-40 Tablet 10's have not been established in children due to limited testing of this drug on children.

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