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  3. Pegeze Syrup 200 ml

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Therapeutic Class

LAXATIVES

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Hari Kumar

Reviewed By

Hari Kumar

MBBS

Last Updated

Jul 8, 2025 | 9:40 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Drug Interactions Checker List

  • PHENYTOIN
  • CARBAMAZEPINE

Drug-Drug Interactions

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Potassium chlorideMepenzolate
Critical
Potassium chlorideCyproheptadine
Critical

Drug-Drug Interactions

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Potassium chlorideMepenzolate
Critical
How does the drug interact with Pegeze Syrup 200 ml:
Taking Mepenzolate and Pegeze Syrup 200 ml(in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Mepenzolate with Pegeze Syrup 200 ml is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.
Potassium chlorideCyproheptadine
Critical
How does the drug interact with Pegeze Syrup 200 ml:
Taking Cyproheptadine with Pegeze Syrup 200 ml can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Cyproheptadine with Pegeze Syrup 200 ml is not recommended, as it can lead to an interaction, can be taken if your doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not stop any medication without talking to a doctor.
Potassium chlorideDifenoxin
Critical
How does the drug interact with Pegeze Syrup 200 ml:
Taking Difenoxin and Pegeze Syrup 200 ml (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
Taking Difenoxin with Pegeze Syrup 200 ml is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately.
Potassium chlorideProcyclidine
Critical
How does the drug interact with Pegeze Syrup 200 ml:
Taking Procyclidine and Pegeze Syrup 200 ml together can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Procyclidine with Pegeze Syrup 200 ml is not recommended, but it can be taken together if advised by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium chlorideDoxepin
Critical
How does the drug interact with Pegeze Syrup 200 ml:
Taking Doxepin with Pegeze Syrup 200 ml can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Doxepin with Pegeze Syrup 200 ml is not recommended, as it can lead to an interaction, but it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), loss of appetite, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium chlorideTolterodine
Critical
How does the drug interact with Pegeze Syrup 200 ml:
Taking Tolterodine and Pegeze Syrup 200 ml together can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Tolterodine and Pegeze Syrup 200 ml, they can be taken if prescribed by a doctor. However, contact a doctor immediately if you develop severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), or less desire to eat. Do not discontinue medications without consulting a doctor.
Potassium chlorideFlavoxate
Critical
How does the drug interact with Pegeze Syrup 200 ml:
Co-administration of Flavoxate with Pegeze Syrup 200 ml can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Flavoxate with Pegeze Syrup 200 ml is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue the medication without consulting a doctor.
Potassium chlorideDimenhydrinate
Critical
How does the drug interact with Pegeze Syrup 200 ml:
Co-administration of Dimenhydrinate and Pegeze Syrup 200 ml can increase the risk of stomach inflammation.

How to manage the interaction:
Co-administration of Dimenhydrinate with Pegeze Syrup 200 ml is generally not recommended, as it can lead to an interaction, it can be taken when a doctor has prescribed it. However, if you experience severe stomach pain, sudden dizziness, vomiting (especially with blood), or dark stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
Potassium chlorideAmitriptyline
Critical
How does the drug interact with Pegeze Syrup 200 ml:
The combination of Amitriptyline and Pegeze Syrup 200 ml may cause stomach and upper intestinal discomfort. (Only applicable to an oral preparation)

How to manage the interaction:
Although co-administration of Amitriptyline and Pegeze Syrup 200 ml is not recommended as it can possibly lead to an interaction, they can be taken if prescribed by a doctor. If you experience severe stomach pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (in particular with blood), decreased hunger, and black stools while taking these medications, consult a doctor immediately. Do not discontinue any medications without talking to a doctor.
Potassium chlorideclidinium bromide
Critical
How does the drug interact with Pegeze Syrup 200 ml:
Taking Pegeze Syrup 200 ml with clidinium bromide may increase the risk of irritant effects of potassium on your stomach and upper intestine.

How to manage the interaction:
Co-administration of Pegeze Syrup 200 ml with clidinium bromide is not recommended, it can be taken if prescribed by the doctor. However, if you experience symptoms such as severe stomach pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), decreased hunger, black, tarry stools, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug Warnings

If you are allergic to Pegeze Syrup or any other medicines, please tell your doctor. If you have ulcerative colitis or Crohn’s disease, inform your doctor before taking Pegeze Syrup . Pegeze Syrup is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please consult a doctor before taking Pegeze Syrup . Drink plenty of fluids while taking Pegeze Syrup . Do not take Pegeze Syrup in more than the recommended doses. Discard Pegeze Syrup after 30 days of first opening the bottle. Do not freeze or refrigerate Pegeze Syrup .

Side Effects of Pegeze Syrup

  • Stomach pain
  • Indigestion
  • Mild diarrhoea
  • Nausea
  • Vomiting

Directions for Use

Use Pegeze Syrup as advised by your doctor. Check the label for directions before use.Oral solution: Dilute it with water as advised by your doctor. Take it by mouth using the measuring cup provided with the pack. Shake the bottle well before each use.Sachet: Dissolve the contents of sachet in water as advised by the doctor. Drink it.

Medicinal Benefits Mweb

Medicinal Benefits

Pegeze Syrup contains Polyethylene glycol, Potassium chloride, Sodium bicarbonate and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools making them easier to pass. Also, it works by cleaning stool from the gastrointestinal tract. Potassium chloride is essential for healthy organ functioning. Sodium bicarbonate works by suppressing high levels of acid in the stomach and helps to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, Pegeze Syrup helps in comfortable bowel movement and provides relief from constipation.

Uses of Pegeze Syrup

Constipation

About Pegeze Syrup

Pegeze Syrup belongs to a class of drugs called laxatives used to treat constipation. Constipation refers to infrequent bowel movements in which the stools are often dry, painful, and hard to pass.

Pegeze Syrup is a combination of four drugs, namely: Polyethylene glycol, Potassium chloride, Sodium bicarbonate, and Sodium chloride. Polyethylene glycol draws water into the intestine and softens stools making them easier to pass. Potassium chloride is essential for healthy organ functioning. Sodium bicarbonate works by suppressing high levels of acid in the stomach and helps to treat acidity and heartburn. Sodium chloride maintains sodium levels in the body. Together, Pegeze Syrup helps in relieving constipation.

Take Pegeze Syrup as advised by your doctor. In some cases, you may experience stomach pain, indigestion, mild diarrhea, nausea, or vomiting. Most of these side effects of Pegeze Syrup do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Pegeze Syrup or any other medicines, please tell your doctor. If you have ulcerative colitis or Crohn’s disease, inform your doctor before taking Pegeze Syrup . Pegeze Syrup is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please consult a doctor before taking Pegeze Syrup . Drink plenty of fluids while taking Pegeze Syrup . Do not take Pegeze Syrup in more than the recommended doses.

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Hari Kumar

Reviewed By

Hari Kumar

MBBS

Last Updated

Jul 8, 2025 | 9:40 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Therapeutic Class

LAXATIVES

All Substitutes & Brand Comparisons

Side effects of Pegeze Syrup 200 ml
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

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Side Effects

Common Side Effects
  • Stomach Pain
  • Stomach rumbles
  • Loose/ Watery Stools
  • Vomiting
  • Nausea
  • Itching
  • Headache

If any of the above side effects continue or intensify, seek medical advice. Professional guidance may be necessary for appropriate care and treatment adjustments.
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