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  1. Home
  2. Medicine

  3. Zyle-100 Tablet 10's

Prescription drug
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Written By ,
Reviewed By Sunny S , MBBS

Composition :

ALLOPURINOL-100MG

Manufacturer/Marketer :

Leeford Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

Therapeutic Class

GOUT THERAPY

Country of origin

India

Manufacturer/Marketer address

Leeford Healthcare Limited , Leo House, Shaheed Bhagat Singh Nagar, Dugri-Dhandra Road, Near Joseph School , Ludhiana-141116.
Other Info - ZYL0041

FAQs

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Zyle-100 Tablet should not be taken along with alcohol as it increases uric acid levels.

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Pregnancy

Caution

Zyle-100 Tablet is a Category C pregnancy drug. If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.

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Breast Feeding

Unsafe

Zyle-100 Tablet is excreted in human breast milk, so it is not recommended during breastfeeding.

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Driving

Unsafe

Zyle-100 Tablet may make some people feel drowsy or sleepy. Do not drive or operate dangerous machinery if you are affected.

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Liver

Caution

Zyle-100 Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Zyle-100 Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Zyle-100 Tablet hasn’t been studied and shouldn’t be used in people younger than 18 years to treat gout or kidney stones.

Product Substitutes

Reference

  1. https://www.medicines.org.uk/emc/files/pil.6006.pdf
  2. https://medlineplus.gov/druginfo/meds/a682673.html
  3. https://www.drugs.com/allopurinol.html

About Zyle-100 Tablet

Zyle-100 Tablet belongs to a class of medication called 'enzyme inhibitor', primarily used to decrease blood uric acid levels in the body. It is used to treat Gout (increased uric acid leading to inflammation), kidney stones, bladder stones. Gout is a type of inflammatory reaction (allergic reaction) to uric acid crystals that form and accumulate inside joints, especially  big toe, due to high uric acid levels in the blood resulting in immense pain in joints. 

Zyle-100 Tablet contains allopurinol, which works by inhibiting the enzyme xanthine oxidase, the enzyme responsible for the formation of uric acid. It stops uric acid formation inside the body without affecting the essential mechanism of cells and the body. 

Take Zyle-100 Tablet as prescribed by your doctor. You are advised to take Zyle-100 Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. The most common side effects of Zyle-100 Tablet are upset stomach, diarrhoea, skin rash, drowsiness. Most of these side effects of Zyle-100 Tablet are temporary, do not require medical attention, and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. 

Do not take Zyle-100 Tablet if you are allergic to any of its ingredients. Zyle-100 Tablet contains monohydrated lactose, if you are intolerant to some sugars, call your doctor before taking this drug. If you are pregnant or planning to get pregnant, are breast-feeding ask your doctor for advice before taking this medicine. Drink at least 2-3 litres of water so that you stay hydrated. For people who have kidney disease or renal dysfunction, dose adjustment is required. If you lose unexplained weight, please visit your doctor immediately.

Uses of Zyle-100 Tablet

Gout (increased uric acid in joints), Kidney stones, Bladder stones

Medicinal Benefits Mweb

Medicinal Benefits

Zyle-100 Tablet contains an 'enzyme inhibitor', medication, primarily used to decrease blood uric acid levels in the body. In addition to this, it is sometimes also used to treat pain caused by pancreas disease, seizures, and improve survival after bypass surgery. It also prevents the rejection of a kidney transplant. Zyle-100 Tablet contains allopurinol, an enzyme inhibitor primarily used to decrease blood uric acid levels in the body. It works by inhibiting the enzyme xanthine oxidase, the enzyme responsible for the formation of uric acid. It stops uric acid formation inside the body without affecting the essential mechanism of cells and the body.

Directions for Use

Take Zyle-100 Tablet with or without food as directed by your physician. Swallow it as a whole with a glass of water. Do not crush, chew, or break it.

Side Effects of Zyle-100 Tablet

  • Upset stomach
  • Diarrhea
  • Nausea
  • Skin rash
  • Drowsiness
  • Feeling or being sick

Drug Warnings

Do not take Zyle-100 Tablet if you are allergic to any of its ingredients. Zyle-100 Tablet  contains monohydrated lactose; if your doctor mentioned that you are intolerant to some sugars, call your doctor before taking this drug. If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine, you have heart problems or high blood pressure and you take diuretics and/or a medicine called ACE-inhibitors, you have thyroid problems. In rare cases, Zyle-100 Tablet can cause bone marrow depression, especially in patients who are already taking that can cause bone marrow depression. For people who have kidney disease or renal dysfunction, dose adjustment is required. If you lose unexplained weight, please visit your doctor immediately. Zyle-100 Tablet can cause drowsiness so do not operate machinery or car as it can impair judgment.

Drug-Drug Interactions

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AllopurinolDidanosine
Critical
AllopurinolTrandolapril
Severe

Drug-Drug Interactions

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AllopurinolDidanosine
Critical
How does the drug interact with Zyle-100 Tablet:
When Didanosine is taken with Zyle-100 Tablet, can increase the blood levels of didanosine.

How to manage the interaction:
Taking Zyle-100 Tablet with Didanosine lead to an interaction, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
AllopurinolTrandolapril
Severe
How does the drug interact with Zyle-100 Tablet:
Co-administration of Zyle-100 Tablet with Trandolapril may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Zyle-100 Tablet and Trandolapril you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not discontinue the medication without consulting a doctor.
AllopurinolCaptopril
Severe
How does the drug interact with Zyle-100 Tablet:
Co-administration of Zyle-100 Tablet with Captopril may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Zyle-100 Tablet and Captopril, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not discontinue the medication without consulting a doctor.
AllopurinolFosinopril
Severe
How does the drug interact with Zyle-100 Tablet:
Co-administration of Zyle-100 Tablet with Fosinopril may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Zyle-100 Tablet and Fosinopril, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not discontinue any medications without consulting a doctor.
AllopurinolMoexipril
Severe
How does the drug interact with Zyle-100 Tablet:
Co-administration of Zyle-100 Tablet with Moexipril may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Zyle-100 Tablet and Moexipril, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also, let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not discontinue any medications without consulting a doctor.
AllopurinolMercaptopurine
Severe
How does the drug interact with Zyle-100 Tablet:
Co-administration of Zyle-100 Tablet with Mercaptopurine together may increase the effects of mercaptopurine.

How to manage the interaction:
If you take Zyle-100 Tablet and Mercaptopurine together, a doctor may adjust the dose or recommend special tests to use both medications safely. However, contact a doctor immediately if you develop any symptoms such as chills, fever, sore throat, mouth sores, body pains, weakness, muscle pain, easy bruising or bleeding, pale stools, darkened urine, or severe nausea, vomiting, and diarrhea. Do not discontinue any medications without a doctor's advice.
AllopurinolPerindopril
Severe
How does the drug interact with Zyle-100 Tablet:
Co-administration of Zyle-100 Tablet with Perindopril may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Zyle-100 Tablet and Perindopril, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms, contact your doctor immediately . Do not discontinue any medications without consulting a doctor.
AllopurinolRamipril
Severe
How does the drug interact with Zyle-100 Tablet:
Co-administration of Zyle-100 Tablet with Ramipril may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Zyle-100 Tablet and Ramipril, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also, let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not discontinue the medication without consulting a doctor.
AllopurinolQuinapril
Severe
How does the drug interact with Zyle-100 Tablet:
Co-administration of Zyle-100 Tablet with Quinapril may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Zyle-100 Tablet and Quinapril, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness, contact your doctor immediately. Also, let your doctor know if you notice signs of infection or experience chills, fever, sore throat, extreme tiredness, body pains, or other flu-like symptoms. Do not discontinue any medications without consulting a doctor.
AllopurinolLisinopril
Severe
How does the drug interact with Zyle-100 Tablet:
Co-administration of Zyle-100 Tablet with Lisinopril may increase the risk of severe allergic reactions and infections.

How to manage the interaction:
Although there is a possible interaction between Zyle-100 Tablet and Lisinopril, you can take these medicines together if prescribed by your doctor. However, if you develop throat tightness, shortness of breath, itching, rash, swelling of the face, lips, or tongue, fever, and/or muscle pain or weakness chills, sore throat, extreme tiredness, body pains, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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ALLOPURINOL-100MGAbnormality of white blood cells, not elsewhere classified
Moderate
ALLOPURINOL-100MGVolume depletion
Moderate

Drug-Diseases Interactions

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ALLOPURINOL-100MGAbnormality of white blood cells, not elsewhere classified
Moderate
How does the disease interact with Zyle-100 Tablet:
Zyle-100 Tablet should be administered cautiously to patients with or predisposed to bone marrow suppression.

How to manage the interaction:
Zyle-100 Tablet should be used with caution in patients with or who are at risk of developing bone marrow suppression.
ALLOPURINOL-100MGVolume depletion
Moderate
How does the disease interact with Zyle-100 Tablet:
Zyle-100 Tablet should be used with caution in patients with dehydration.

How to manage the interaction:
Zyle-100 Tablet should be used with caution in patients with dehydration. Adequate hydration is necessary during treatment with Zyle-100 Tablet.
ALLOPURINOL-100MGAlcoholic liver disease
Moderate
How does the disease interact with Zyle-100 Tablet:
Zyle-100 Tablet should be administered cautiously in patients with liver disease.

How to manage the interaction:
Zyle-100 Tablet should be used with caution in patients with liver disease. Regular monitoring of liver function tests is recommended in these patients during the early stages of therapy.
ALLOPURINOL-100MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Zyle-100 Tablet:
Zyle-100 Tablet should be used with caution in patients with renal dysfunction.

How to manage the interaction:
Zyle-100 Tablet should be used with caution in kidney failure patients. Kidney function should be monitored during the initial stages of therapy, and the dosage reduced or the drug withdrawn if necessary.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • CAPTOPRIL
  • AMPICILLIN
  • AMOXICILLIN
  • DICOUMAROL
  • PHENPROCOUMON
  • WARFARIN
  • CHLORPROPAMIDE
  • TOLBUTAMIDE
  • PHENYTOIN
  • CARBAMAZEPINE
  • AZATHIOPRINE
  • MERCAPTOPURINE
  • CYCLOPHOSPHAMIDE
  • CYCLOSPORINE
  • THEOPHYLLINE

Habit Forming

No

Special Advise

  • Drink at least 8 glasses of water or other fluids each day while taking Zyle-100 Tablet unless directed to do otherwise by your doctor. If you are a kidney patient consult a doctor before any fluid intake. 
  • If you are intolerant to sugars, please mention your doctor before starting Zyle-100 Tablet .
  • The doctor will monitor your kidney function constantly before and during you take Zyle-100 Tablet .
  • A liver function test should be done regularly to monitor liver enzymes as Zyle-100 Tablet can cause liver enzyme fluctuations.

Diet & Lifestyle Advise

  • Purines are found in certain foods such as alcohol, fish, meat, bacon. People with gout should restrict or avoid them greatly.
  • Losing weight helps lower the levels of uric acid.
  • It is also beneficial to drink plenty of fluids. However, the restricted use of alcohol and tobacco is recommended, raising the levels of uric acid.
  • Maintain a diet that is rich in fruits, vegetables, whole grains, and low-fat dairy products.

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