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Zrepag-2 MF Tablet 10's

Zrepag-2 MF Tablet 10's

About Zrepag-2 MF Tablet 10's

Zrepag-2 MF Tablet 10's belongs to a class of medicine known as an antidiabetic. It is a combination of two antidiabetic drugs: Repaglinide and Metformin. Type 2 diabetes is a chronic or lifelong condition affecting how your body processes glucose. People with type 2 diabetes either do not produce enough insulin or if the insulin is produced, it cannot perform its function in the body (insulin resistance). Due to this, the blood glucose level increases, and symptoms such as frequent urination, increased thirst, and increased hunger start. It can lead to serious complications like skin infection, eye problems (retinopathy), nerve damage (neuropathy), diabetic foot (foot ulcer), kidney disease (nephropathy), high blood pressure, and even stroke.

Repaglinide acts by increasing the amount of insulin released by the pancreas. It starts acting so quickly on controlling blood sugar levels immediately after a meal. On the other hand, Metformin, which is a 'biguanide', acts by lowering the liver's glucose production, delaying glucose absorption from the intestines, and increasing the body's response to insulin. In a nutshell, the two medicines prevent blood glucose levels from rising to very high levels, thus keeping your Diabetes under control. Zrepag-2 MF Tablet 10's act together to keep your blood sugar levels under check. The strict control of blood sugars is essential to mention the many disabling side effects of Diabetes. Zrepag-2 MF Tablet 10's shows optimum effects when taken along with healthy lifestyle changes like weight loss, regular exercise, healthy diet, etc.

Zrepag-2 MF Tablet 10's should be taken with food to avoid an upset stomach. Zrepag-2 MF Tablet 10's should be taken at the same time of the day each time for the best results. Your doctor will decide what dose should be taken for better advice, which can change quickly depending on your condition. A common side effect of Zrepag-2 MF Tablet 10's is hypoglycaemia (low blood glucose levels), characterized by dizziness, sweating, palpitations, hunger pangs, dry mouth, skin, etc. So, to avoid hypoglycaemia, you should not miss meals and also should carry some form of sugar along with you. Other side effects include taste change, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms.

You should not take Zrepag-2 MF Tablet 10's if you have renal impairment, metabolic acidosis, including diabetic ketoacidosis (excess acids in your blood), and receiving gemfibrozil (used to treat abnormal blood lipid levels). Zrepag-2 MF Tablet 10's should not be stopped even if you feel better, without consulting your doctor as your sugar level keeps changing. If you stop taking Zrepag-2 MF Tablet 10's abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy), and nerve damage (neuropathy). Zrepag-2 MF Tablet 10's should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease. Please inform your doctor if you have any heart disease, are planning to get pregnant, or are breastfeeding.

Uses of Zrepag-2 MF Tablet 10's

Type 2 Diabetes Mellitus

Medicinal Benefits

Zrepag-2 MF Tablet 10's should be taken with food to avoid an upset stomach. Zrepag-2 MF Tablet 10's should be taken at the same time of the day each time for the best results. Your doctor will decide what dose should be taken for better advice, which can change quickly depending on your condition. A common side effect of Zrepag-2 MF Tablet 10's is hypoglycaemia (low blood glucose levels), characterised by dizziness, sweating, palpitations, hunger pangs, dry mouth, skin, etc. To avoid hypoglycaemia, you should not miss meals and should carry some form of sugar along with you. Other side effects include taste change, nausea, diarrhoea, stomach pain, headache, and upper respiratory symptoms.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Zrepag-2 MF Tablet 10's

  • Dizziness
  • Sweating
  • Palpitations
  • hunger pangs
  • Dry mouth and skin
  • Hypoglycaemia (low blood glucose level)

Drug Warnings

Some diabetic patients taking Zrepag-2 MF Tablet 10's may develop a rare but serious condition called lactic acidosis. In this condition, too much lactic acid is accumulated in the blood. So, your liver and kidney's proper functioning is required to eliminate excess lactic acid from the blood. You should not take Zrepag-2 MF Tablet 10's if you have kidney disease, as measured by a blood test. Zrepag-2 MF Tablet 10's may lower vitamin B12 levels, so try to have blood tests for annual blood and vitamin. Zrepag-2 MF Tablet 10's, when used with or without insulin, tends to lower the blood sugar level extremely. So, the doctor may lower the dose of insulin. Zrepag-2 MF Tablet 10's may lower your thyroid-stimulating hormone (TSH), so an annual check-up of TSH is suggested.

Drug Interactions

Drug-Drug Interactions: Zrepag-2 MF Tablet 10's may interact with insulin, high blood pressure-lowering pills (hydrochlorothiazide, amlodipine), water pills/diuretics (furosemide), heart failure-related medicines (digoxin), anti-hypertensive (metoprolol), steroids (prednisolone), thyroid hormones etc. So, tell your doctor if you are using these drugs before taking Zrepag-2 MF Tablet 10's.

Drug-Food Interactions: Taking Zrepag-2 MF Tablet 10's with alcoholic beverages may increase the risk of a rare but serious and potentially life-threatening condition known as lactic acidosis (build-up of lactic acid in the blood) or hypoglycemia.

Drug-Disease Interactions: Zrepag-2 MF Tablet 10's should be avoided in patients with vitamin B12 deficiency, kidney problems, liver problems, cardiovascular disease (heart-related issues), and low blood sugar level (hypoglycemia) may worsen the condition.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • INSULIN GLARGINE
  • LEVOTHYROXINE SODIUM
  • METOPROLOL
  • SITAGLIPTIN
  • FUROSEMIDE
  • GLIPIZIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Fill your half plate with starchy veggies, a quarter with proteins, and a quarter with whole grains.
  • Eat at regular intervals. Do not take the long gap between a meal or snack.
  • Monitor your blood sugar level regularly, especially when there are a lot of fluctuations.
  • Invest in at least 150 minutes of moderate-intensity physical activity and 15 minutes of high-intensity exercise weekly.
  • Lose weight gradually to achieve a healthy body mass index (18.5 to 24.9).
  • Replace refined carbohydrates containing whole-grain foods and increase the intake of fruits, veggies, and other fibre-enriched foods.
  • Reduce saturated fat (or hidden fats) intake in food like chips, crisps, pastries, biscuits, and samosas. Choose omega-3 fatty acid-containing oils for daily cooking. For frying, you may use palm oil, mustard oil, groundnut oil, rice bran oil, and safflower oil.
  • Do not take stress as it may elevate your blood sugar level. You may adopt stress management techniques like mindfulness, yoga, or meditation to control stress-related blood sugar changes.
  • Opt for low-fat dairy products (low-fat yoghurt, fat-free milk, cheese, etc.).
  • Keep your blood pressure as normal (120/80) as possible, as it reduces the risk of cardiovascular diseases in diabetes patients.

Special Advise

  • Keep taking the drug even if you think your blood sugar levels are under control. If you miss a dose, do not take a larger dose, cons. Consulttreating physician for advice.
  • Take short, frequent meals, avoid prolonged fasting when taking this drug. Beware of hypoglycaemia symptoms include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination, etc. Whenever you experience the above-mentioned symptoms, immediately consume 5-6 candies, three glucose biscuits, or three teaspoons of honey/sugar and get in touch with your physician. Make sure to carry these with you at all times, especially for long travels. 
  • Before the doctor prescribes this medicine, it is always better that your physician knows about any underlying conditions like kidney or liver disease, prior heart attack, alcohol intake, etc.
  • Avoid drinking alcohol while on this drug as it increases the risk of hypoglycaemia (a decrease in blood sugar which might be fatal in some cases) and lactic acidosis (when the lactic acid increases in the body, impacting the functioning of various organs in the body).
  • Try to quit smoking and reduce carbohydrate-rich food like potatoes, mangoes, bread, sugar etc.
  • Remember, lifestyle modifications are the most important step in controlling blood sugar levels.

Disease/Condition Glossary

Type 2 diabetes is a condition where the body cannot make sufficient insulin, or the insulin that it makes doesn't work properly or is utilized by our body. This can cause high blood sugar levels (hyperglycaemia). Type 2 diabetes symptoms include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, and blurred vision. There may be weight gain in some cases, while in rare cases, weight loss may be observed. The complication of type 2 diabetes also includes neuropathy (nerve problems), nephropathy (kidney problems), and retinopathy (damaged retina of eyes or blindness), loss of limbs, sexual dysfunction, and an increase in the chance of heart attack or stroke.

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