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  1. Home
  2. Medicine

  3. Zidolam N Tablet 60's

Prescription drug
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Written By ,
Reviewed By Sunny S , MBBS

Composition :

LAMIVUDINE-150MG + NEVIRAPINE-200MG + ZIDOVUDINE-300MG

Manufacturer/Marketer :

Hetero Drugs Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIRETROVIRAL AGENTS

Country of origin

INDIA

Manufacturer/Marketer address

7-2-A2, Hetero Corporate, Industrial Estates, Sanath Nagar, Hyderabad – 500 018. Telangana, INDIA
Other Info - ZID0044

FAQs

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

ZIDOLAM N 300/150/200MG TABLET with alcohol causes liver damage. so Inform Your doctor while prescribing the ZIDOLAM N 300/150/200MG TABLET .

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Pregnancy

Caution

ZIDOLAM N 300/150/200MG TABLET can be used in pregnancy by the advice of your doctor because studies do not show any defects in the unborn baby as ZIDOLAM N 300/150/200MG TABLET passes through the placenta.

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Breast Feeding

Caution

ZIDOLAM N 300/150/200MG TABLET can be used in breastfeeding mothers by the advice of your doctor because studies do not show any defects in baby as ZIDOLAM N 300/150/200MG TABLET passes through breast milk.

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Driving

Unsafe

ZIDOLAM N 300/150/200MG TABLET may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.

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Liver

Caution

If you take ZIDOLAM N 300/150/200MG TABLET , Your doctor may monitor your liver functions regularly. Inform your doctor if you develop abdominal pain symptoms, loss of appetite, yellowing of the eyes or skin. If needed dose adjustments can be made by your doctor.

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Kidney

Caution

If you take ZIDOLAM N 300/150/200MG TABLET , Your doctor may monitor your kidney functions regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite darkened urine. If needed dose adjustments can be done by your doctor.

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Children

Unsafe

ZIDOLAM N 300/150/200MG TABLET cannot be used in children below 12 years. If their age is >35 can be prescribed and dose adjustments can be done by your doctor.

Product Substitutes

Reference

  1. https://www.drugs.com/ppa/lamivudine-nevirapine-and-zidovudine.html
  2. https://www.accessdata.fda.gov/drugsatfda_docs/pepfar/022061PI.pdf
  3. https://www.rxwiki.com/zidovudine-lamivudine-and-nevirapine
  4. https://medlineplus.gov/druginfo/meds/a601066.html#:~:text=The%20combination%20of%20lamivudine%20and,of%20HIV%20in%20t

About ZIDOLAM N 300/150/200MG TABLET

ZIDOLAM N 300/150/200MG TABLET is a combination of three drugs: lamivudine, zidovudine, and nevirapine. ZIDOLAM N 300/150/200MG TABLET works by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body and also increasing the CD4 cell (white blood cells that protect against infection) count in your blood. ZIDOLAM N 300/150/200MG TABLET is generally prescribed for the treatment of HIV infection.

lamivudine and zidovudine is nucleosidase reverse transcriptase inhibitor, both medicines together decrease the amount of virus in your body by inhibiting HIV reverse transcription via viral DNA chain termination, whereas Niverapine is a non-nucleosidase reverse transcriptase inhibitor, works by lowering the amount of HIV in the blood. ZIDOLAM N 300/150/200MG TABLET  will not cure HIV infection or AIDS, however, it helps keep HIV from reproducing and appears to slow down the destruction of the immune system.

Take ZIDOLAM N 300/150/200MG TABLET by mouth with a glass full of water.  Take it on an empty stomach, preferably at bedtime, to reduce side effects. Skipping doses increases the risk of treatment failure. Make sure that you take all your doses at the correct time. Common side effects of ZIDOLAM N 300/150/200MG TABLET are Nausea, Vomiting, Diarrhea, Headache, Tiredness, Insomnia (difficulty in sleeping), Rash, Muscle damage, Anemia (low number of red blood cells), and Decreased white blood cell count (neutrophils).

ZIDOLAM N 300/150/200MG TABLET should not be prescribed for people who are allergic to any one of the components in the name. $ name carries a boxed warning for the risk of life-threatening (including fatal) hepatotoxicity, skin reactions, hematologic toxicity, myopathy, lactic acidosis and severe hepatomegaly with steatosis, and exacerbations of hepatitis B. ZIDOLAM N 300/150/200MG TABLET may cause dizziness or sleepiness, so don't drive or do anything requiring concentration until you know how it affects you. It can cause birth defects, use effective contraception while taking ZIDOLAM N 300/150/200MG TABLET , and 12 weeks after stopping it. Skipping doses increases the risk of treatment failure. Make sure that you take all your doses at the correct time. Do not stop taking ZIDOLAM N 300/150/200MG TABLET without your doctor’s advice.

Uses of ZIDOLAM N 300/150/200MG TABLET

Human immunodeficiency virus infection

Medicinal Benefits Mweb

Medicinal Benefits

ZIDOLAM N 300/150/200MG TABLET is a combination of three medicines that slows down or stops the progression of HIV infections. ZIDOLAM N 300/150/200MG TABLET work by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood. ZIDOLAM N 300/150/200MG TABLET is also used in preventing pregnancy complications.

Directions for Use

Take it on an empty stomach, preferably at bedtime, to reduce side effects or take it as advised by the doctor. Swallow it as a whole with a glass of water. Skipping doses increases the risk of treatment failure. Make sure that you take all your doses at the correct time.

Side Effects of ZIDOLAM N 300/150/200MG TABLET

  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Tiredness
  • Insomnia (difficulty in sleeping)
  • Rash
  • Muscle damage
  • Anemia (low number of red blood cells)
  • Decreased white blood cell count (neutrophils)
  • Chills and fever
  • Indigestion
  • Difficulty with bowel movements

Drug Warnings

ZIDOLAM N 300/150/200MG TABLET should not be prescribed for people who are allergic to any one of the components in the name. ZIDOLAM N 300/150/200MG TABLET carries a boxed warning for the risk of life-threatening (including fatal) hepatotoxicity, skin reactions, hematologic toxicity, myopathy, lactic acidosis and severe hepatomegaly with steatosis, and exacerbations of hepatitis B. ZIDOLAM N 300/150/200MG TABLET may cause dizziness or sleepiness, so don't drive or do anything requiring concentration until you know how it affects you. Skipping doses increases the risk of treatment failure. Make sure that you take all your doses at the correct time. Do not stop taking ZIDOLAM N 300/150/200MG TABLET without your doctor’s advice.

Drug-Drug Interactions

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LamivudineEmtricitabine
Critical
NevirapineAtazanavir
Critical

Drug-Drug Interactions

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LamivudineEmtricitabine
Critical
How does the drug interact with Zidolam N Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Taking Emtricitabine with Zidolam N Tablet is not recommended, but it can be taken if your doctor prescribes it. Contact your doctor if your symptoms do not improve. Do not stop taking any medication without consulting your doctor.
NevirapineAtazanavir
Critical
How does the drug interact with Zidolam N Tablet:
When Atazanavir is taken with Zidolam N Tablet, it can reduce the levels and side effects of atazanavir & increase the blood levels and effects of Zidolam N Tablet.

How to manage the interaction:
Taking Zidolam N Tablet with Atazanavir is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience a rash on any parts of your body, loss of appetite, nausea, vomiting, jaundice (yellowing of the skin and/or eyes), dark-coloured urine, pale-coloured stools, or pain or ache in the right abdominal area below your ribs, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NevirapineRanolazine
Critical
How does the drug interact with Zidolam N Tablet:
Co-administration of Zidolam N Tablet with Ranolazine may significantly reduce the blood levels of Ranolazine. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Zidolam N Tablet with Ranolazine is generally avoided as it can lead to an interaction, they can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
LamivudineTeriflunomide
Severe
How does the drug interact with Zidolam N Tablet:
Teriflunomide can cause Zidolam N Tablet to stay in the body longer, leading to higher levels in the blood.

How to manage the interaction:
Although there is a possible interaction between Zidolam N Tablet and Teriflunomide, you can take these medicines together if prescribed by your doctor. If you have any of these signs and symptoms, contact your doctor immediately: fever, chills, pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, or bleeding. Do not discontinue any medications without consulting your doctor.
LamivudineMipomersen
Severe
How does the drug interact with Zidolam N Tablet:
Taking Zidolam N Tablet and mipomersen together can increase the risk of liver damage.

How to manage the interaction:
Although taking Zidolam N Tablet and Mipomersen together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include fever, rash, itching, loss of appetite, feeling sick, feeling tired, pain in the upper right side of your belly, dark urine, yellowing of the skin or eyes, chills, joint pain, swelling, bruising, loss of appetite, and bleeding. Do not stop using any medications without talking to your doctor.
LamivudineLeflunomide
Severe
How does the drug interact with Zidolam N Tablet:
Combining Zidolam N Tablet with Leflunomide can increase the risk and severity of muscle problems.

How to manage the interaction:
Although there is a possible interaction between Zidolam N Tablet and Leflunomide, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms it's important to contact your doctor right away: fever, feeling cold, joint discomfort, swelling, bruising, skin irritation, itching, not feeling hungry, tiredness, feeling sick, stomach ache, dark urine or bleeding. Do not stop using any medications without talking to your doctor.
LamivudineLomitapide
Severe
How does the drug interact with Zidolam N Tablet:
Taking Zidolam N Tablet and lomitapide together can increase the risk of liver damage

How to manage the interaction:
There may be a possibility of interaction between Zidolam N Tablet and Lomitapide, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include fever, rash, itching, loss of appetite, feeling sick, feeling tired, feeling unwell, pain in the upper right side of your stomach, dark urine, yellowing of the skin or eyes, chills, joint pain, swelling, bruising, stomach pain, liver damage, or bleeding. Do not stop using any medications without a doctor's advice.
LamivudineZalcitabine
Severe
How does the drug interact with Zidolam N Tablet:
Combining these two medications may reduce overall effectiveness due to potential antagonistic effects (opposite actions).

How to manage the interaction:
Although there is a possible interaction between Zidolam N Tablet and Zalcitabine, you can take these medicines together if prescribed by your doctor. Contact your doctor if your symptoms do not improve. Do not discontinue any medications without consulting your doctor.
LamivudineBexarotene
Severe
How does the drug interact with Zidolam N Tablet:
Taking bexarotene together with Zidolam N Tablet increases the risk of pancreatitis (inflammation of the pancreas).

How to manage the interaction:
There may be a possibility of interaction between Zidolam N Tablet and Bexarotene, but it can be taken if prescribed by a doctor. If you're having symptoms like nausea, vomiting, or abdominal pain, contact your doctor right away. Do not discontinue any medications without consulting your doctor.
LamivudineSorbitol
Severe
How does the drug interact with Zidolam N Tablet:
Zidolam N Tablet can cause higher levels of Sorbitol in the blood by reducing its excretion rate.

How to manage the interaction:
Taking Sorbitol with Zidolam N Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • EFAVIRENZ
  • INDINAVIR
  • RITONAVIR
  • CHLORAMPHENICOL
  • CARBAMAZEPINE
  • FLUCONAZOLE
  • KETOCONAZOLE
  • GANCICLOVIR
  • LOPINAVIR

Habit Forming

No

Special Advise

  • Take it on an empty stomach, preferably at bedtime, to reduce side effects.
  • Skipping doses increases the risk of treatment failure. Make sure that you take all your doses at the correct time.
  • $ name can cause congenital disabilities. Use effective contraception while taking Lamivudine + Zidovudine + Nevirapine and 12 weeks after stopping it.
  • ZIDOLAM N 300/150/200MG TABLET may cause the weakening of your bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.
  • Your doctor may monitor your kidney and liver functions regularly. Inform your doctor if you develop abdominal pain, loss of appetite, darkened urine, or yellowing of the eyes or skin.

Diet & Lifestyle Advise

  • Getting moderate exercise. Being physically active three to six times a week can help improve your mood and outlook and improve your overall quality of life.
  • quit smoking and avoid alcohol
  •  Take healthy diet for someone living with HIV is one that is rich in whole grains, low-fat dairy products, protein, and lots of fresh fruits and vegetables.
  •  If you have HIV, you can get infections more easily. so always wash your hands well and often, and practice good food safety to avoid foodborne illness.

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