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  1. Home
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  3. Zam-MT 0.5 Tablet 10's

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Zam-MT 0.5 Tablet 10's, Pack of 10 TABLETS
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Written By ,
Reviewed By Sunny S , MBBS

Composition :

ALPRAZOLAM-0.5MG+MELATONIN-3MG

Manufacturer/Marketer :

East West Pharma India Pvt Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

[SEDATIVE-HYPNOTIC DRUGS]

Country of origin

India

Manufacturer/Marketer address

6, Nandalal Bose Sarani,Kolkata -700071.
Other Info - ZAM0021

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Safe if prescribed

Alcohol is sedative in nature, so taking it with Zam-MT 0.5 Tablet may interrupt the sleep cycle. Alcohol may worsen the effects of Zam-MT 0.5 Tablet so one should not consume it with Zam-MT 0.5 Tablet .

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Pregnancy

Consult your doctor

Zam-MT 0.5 Tablet is a category D pregnancy drug. It is not recommended for use during pregnancy, especially in the second and third trimesters as it may cause harm to the unborn baby.

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Breast Feeding

Consult your doctor

Avoid breastfeeding while taking Zam-MT 0.5 Tablet as it may be excreted in breast milk and cause adverse effects in the baby.

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Driving

Safe if prescribed

Zam-MT 0.5 Tablet may cause dizziness, double vision, or drowsiness in some people. It is an offence to drive if Zam-MT 0.5 Tablet affects you. Therefore, avoid driving if you feel drowsy, dizzy, or experience any vision problems after taking Zam-MT 0.5 Tablet .

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Liver

Consult your doctor

Take Zam-MT 0.5 Tablet with caution, especially if you have or had a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Consult your doctor

Take Zam-MT 0.5 Tablet with caution, especially if you have or had a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Safe if prescribed

Not enough scientific data available for Zam-MT 0.5 Tablet , hence it is best to consult a child specialist.

Product Substitutes

Reference

  1. https://www.drugs.com/melatonin.html
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/018276s052lbl.pdf

About Zam-MT 0.5 Tablet

Zam-MT 0.5 Tablet belongs to a class of medication called sedatives and hypnotics, primarily used to treat sleeplessness (insomnia). Besides this, it also helps to provide a calming effect on anxiety disorder and panic disorder. Insomnia is a sleeping disorder in which a person finds difficulty in falling asleep or staying asleep. Due to anxiety and panic disorder, a person cannot sleep due to disturbances in their circadian cycle and hormonal imbalance in the brain like melatonin. 

Zam-MT 0.5 Tablet is a combination of two medicines: Alprazolam and Melatonin, which helps a person fall asleep faster and stay asleep during the night. Alprazolam is a benzodiazepine (BZD) that increases the activity of a chemical messenger in the brain known as GABA, reducing the abnormal and overactivity of brain cells (neurons), which in turn relaxes the brain and promotes sleep. On the other hand, Melatonin is a natural hormone that activates the ON-OFF mechanism of a person's sleeping-waking cycle (circadian cycle), thereby inducing sleep during the nighttime. 

Take Zam-MT 0.5 Tablet with or without food and swallow whole with a glass of water. Do not break, crush, or chew it. Your doctor will advise you how often you take Zam-MT 0.5 Tablet based on your medical condition. The most common side effects of Zam-MT 0.5 Tablet include drowsiness, tiredness, headache, depressed mood, daytime drowsiness, stomach pain, and dizziness. Most of these side effects of Zam-MT 0.5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Tell your doctor if you have an ongoing medical condition, including depression, diabetes, an autoimmune disorder, or high blood pressure. If you are known to be allergic to Zam-MT 0.5 Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, inform your doctor before taking Zam-MT 0.5 Tablet . Zam-MT 0.5 Tablet should be used with caution in elderly patients as there is an increased risk of adverse reactions such as dizziness, muscle weakness, and drowsiness.

Uses of Zam-MT 0.5 Tablet

Insomnia (sleeplessness) 

Medicinal Benefits Mweb

Key Benefits

Zam-MT 0.5 Tablet belongs to a class of sedatives and hypnotics, primarily used to treat insomnia (difficulty in falling asleep or staying asleep). Zam-MT 0.5 Tablet is a combination of two medicines: 'Alprazolam' and  'Melatonin', which helps a person fall asleep faster and stay asleep during the night, which has been disturbed due to anxiety or panic disorder. Zam-MT 0.5 Tablet helps relax the brain's exciting chemicals (GABA), allowing a person to sleep easily and stay asleep during the whole night without any disturbance.  

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Zam-MT 0.5 Tablet

  • Tiredness
  • Dizziness
  • Headache
  • Drowsiness
  • Stomach pain
  • Depressed mood

Drug Warnings

Before your doctor prescribes your Zam-MT 0.5 Tablet , you should tell your doctor if you have allergies or not. With it, also tell if you are pregnant or breastfeeding as the use of this medication is restricted to be used in pregnancy and breastfeeding. Elderly people are more responsive to the side effects of the drug, so they should tell every product, including the herbal ones to their doctor so that doctor can decide the dosage for them. Inform your doctor about myasthenia gravis (muscle weakness), drug addiction, chronic pulmonary insufficiency, narrow-angle glaucoma, and kidney/liver problem before taking Zam-MT 0.5 Tablet . Do not take Zam-MT 0.5 Tablet with opioids as it may cause breathing problems, drowsiness and coma.

Drug-Drug Interactions

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AlprazolamSodium oxybate
Critical
AlprazolamCeritinib
Critical

Drug-Drug Interactions

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AlprazolamSodium oxybate
Critical
How does the drug interact with Zam-MT 0.5 Tablet:
Co-administration of Zam-MT 0.5 Tablet with Sodium Oxybate may increase Sodium Oxybate's adverse effects (respiratory depression, low blood pressure, fainting).

How to manage the interaction:
Although the combination of Zam-MT 0.5 Tablet and sodium oxybate may cause an interaction, they can be used if prescribed by a doctor. Consult a doctor if you suffer any of the following symptoms: breathing difficulties, low blood pressure, being severely drowsy, or fainting. Avoid driving or operating hazardous machinery or performing other hazardous activities for at least 6 hours after taking a dose. Do not discontinue any medications without consulting a doctor.
AlprazolamCeritinib
Critical
How does the drug interact with Zam-MT 0.5 Tablet:
Co-administration of Zam-MT 0.5 Tablet with Ceritinib may considerably increase the blood levels and effects of Zam-MT 0.5 Tablet.

How to manage the interaction:
Although there is a interaction between Zam-MT 0.5 Tablet and Ceritinib, it can be taken if prescribed by a doctor. Consult a doctor if you experience excessive or prolonged drowsiness or difficulty in breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamKetoconazole
Critical
How does the drug interact with Zam-MT 0.5 Tablet:
Co-administration of Zam-MT 0.5 Tablet with Ketoconazole may considerably increase the blood levels of Zam-MT 0.5 Tablet, which may result in side effects.

How to manage the interaction:
Although there is an interaction between Zam-MT 0.5 Tablet and Ketoconazole, it can be taken if prescribed by a doctor. Consult a doctor if you experience excessive or prolonged drowsiness or difficulty in breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamDelavirdine
Critical
How does the drug interact with Zam-MT 0.5 Tablet:
The combination of Zam-MT 0.5 Tablet and Delavirdine may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Zam-MT 0.5 Tablet and Delavirdine, it can be used if prescribed by a doctor. Consult a doctor if you have sleepiness, dizziness, confusion, or weak or rapid breathing over a long duration of time. Do not discontinue any medications without consulting a doctor.
AlprazolamClarithromycin
Critical
How does the drug interact with Zam-MT 0.5 Tablet:
The combination of Zam-MT 0.5 Tablet and clarithromycin may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Zam-MT 0.5 Tablet and clarithromycin, it can be used if prescribed by a doctor. Consult a doctor if you have excessive drowsiness, problems with movement, memory loss, anxiety, hallucinations (illogical thoughts), or breathing issues (particularly if you have asthma or obstructive sleep apnea). Do not discontinue any medications without consulting a doctor.
AlprazolamItraconazole
Critical
How does the drug interact with Zam-MT 0.5 Tablet:
Zam-MT 0.5 Tablet's blood levels may be significantly raised when combined with itraconazole.

How to manage the interaction:
Although combining Zam-MT 0.5 Tablet and Itraconazole may lead to an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you get extremely drowsy and your breathing becomes slow. Without consulting a doctor, never stop taking any medication.
AlprazolamIndinavir
Critical
How does the drug interact with Zam-MT 0.5 Tablet:
The combination of Zam-MT 0.5 Tablet and Indinavir may considerably increase the risk of side effects.

How to manage the interaction:
Despite the fact that there is an interaction between Zam-MT 0.5 Tablet and Indinavir, it can be used if prescribed by a doctor. Consult a doctor if you have drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamCobicistat
Critical
How does the drug interact with Zam-MT 0.5 Tablet:
Co-administration of Zam-MT 0.5 Tablet with Cobicistat may considerably increase the blood levels and effects of Zam-MT 0.5 Tablet.

How to manage the interaction:
Despite the fact that there is an interaction between Zam-MT 0.5 Tablet and Cobicistat, it can be taken if prescribed by a doctor. Consult a doctor if you experience excessive or prolonged drowsiness or difficulty in breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamPerindopril
Severe
How does the drug interact with Zam-MT 0.5 Tablet:
Taking Zam-MT 0.5 Tablet with Perindopril shows additive effects which may increase their efficacy and side effects. Increased Zam-MT 0.5 Tablet levels may alter blood pressure.

How to manage the interaction:
Taking Zam-MT 0.5 Tablet with Perindopril can show additive efficacy, it can be taken if your doctor has advised it. Contact your doctor immediately if you experience signs such as slurred speech, drowsiness, confusion, blurry visions, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
AlprazolamAlfentanil
Severe
How does the drug interact with Zam-MT 0.5 Tablet:
Using Zam-MT 0.5 Tablet together with Alfentanil can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although the combination of Zam-MT 0.5 Tablet and Alfentanil may cause an interaction, they can be used if prescribed by a doctor. Consult a doctor if you have any symptoms such as dizziness, drowsiness, difficulty concentrating, or impairment in judgment, reaction speed, or control of movements. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • FLUOXETINE
  • NEFAZODONE
  • ERYTHROMYCIN
  • RIFABUTIN
  • KETOCONAZOLE
  • MORPHINE
  • CODEINE
  • DIHYDROCODEINE
  • BUPRENORPHINE

Habit Forming

Yes

Special Advise

  • Do not take Zam-MT 0.5 Tablet for a prolonged time as it may lead to mental or physical dependence on Zam-MT 0.5 Tablet .

Diet & Lifestyle Advise

  • Keeping a fixed time to go to bed and wake up consistently every day helps maintain a better sleeping and waking plan.
  • Engage yourself in workouts, dancing, and walking that help promote calmness in the body so that you can enjoy a good night's sleep.
  • Taking naps in a day can make it harder to fall asleep at night, so one should try to limit a nap to no more than half an hour and don't nap after 2 p.m. 
  • Limit caffeine and alcohol consumption as it will not let you sleep and causes frequent urination.
  • Avoid large, heavy meals before bed. One can have a light snack that helps to avoid heartburn.
  • Avoid consumption of alcohol as it may increase drowsiness.
  • Take less liquid before bedtime so that you won't have to urinate as often. One must keep their worries and planning aside and enjoy a warm bath or a massage before bedtime. It will help in having a good night's relaxing sleep.

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