VONADAY TABLET

VONADAY TABLET belongs to the class of ‘antiretrovirals,’ used to treat HIV infection. VONADAY TABLET helps in decreasing the chance of developing AIDS (acquired immunodeficiency syndrome). HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses.

VONADAY TABLET is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil. Efavirenz is a non-nucleoside reverse transcriptase inhibitor. Lamivudine is a nucleoside reverse transcriptase inhibitor. Tenofovir disoproxil is a nucleotide reverse transcriptase inhibitor. They work by inhibiting the reverse transcriptase enzyme, which is essential for the reproduction of the virus. 

Your doctor will decide the dosage based on your medical condition. Sometimes, VONADAY TABLET may have common side effects like nausea, headache, dizziness, depression, sleeping problems, weakness, tiredness, cough, rash, unusual dreams, concentration problems, drowsiness (sleepiness), and diarrhoea. These side effects do not require medical attention and gradually resolve over time. However, if these side effects persist for a longer time, please seek medical advice.

Let your doctor know if you are using a prescription, non-prescription drugs, and herbal products before starting VONADAY TABLET. If you are known to be allergic to VONADAY TABLET or its inactive components, please inform your doctor. Please tell your doctor if you have any heart problems, liver or kidney diseases, alcohol addiction, fits, high cholesterol levels, and weak/broken bones. If you are pregnant, please consult your doctor before taking VONADAY TABLET. Do not breastfeed while taking VONADAY TABLET. VONADAY TABLET is recommended for children who weigh at least 77 pounds (35 kg).

VONADAY TABLET is used to treat HIV infection. It consists of three medicines, namely: Efavirenz, Lamivudine, and Tenofovir disoproxil. Efavirenz belongs to the class of non-nucleoside reverse transcriptase inhibitors. Lamivudine is a nucleoside reverse transcriptase inhibitor, whereas Tenofovir disoproxil is a nucleotide reverse transcriptase inhibitor. They work by inhibiting the reverse transcriptase enzyme, which is essential for the reproduction of the virus. 

• Nausea
• Headache
• Dizziness
• Depression
• Sleeping problems
• Weakness
• Tiredness
• Cough
• Rash
• Unusual dreams
• Concentration problems
• Drowsiness (sleepiness)
• Diarrhoea

Let your doctor know if you are using a prescription, non-prescription drugs, and herbal products before starting VONADAY TABLET. Inform your doctor if you are allergic to VONADAY TABLET or its inactive components. Please inform your doctor if you have heart problems, liver (hepatitis B or C, cirrhosis) or kidney diseases, depression, pancreas (inflammation of the pancreas), alcohol addiction, fits, high cholesterol levels, and weak/broken bones (osteoporosis). You are advised to take proper precautions if you are infected with HIV infection to prevent the spread of infection to others through sexual contact or body fluids. VONADAY TABLET should be used with caution due to the increased risk of immune reconstitution syndrome, decreased bone mineral density, pancreatitis, and lactic acidosis. Pregnant women should consult their doctor before taking VONADAY TABLET. It is not recommended to breastfeed while using VONADAY TABLET since it excretes into the breast milk. VONADAY TABLET may cause dizziness/drowsiness, so do not drive or operate heavy machinery if you feel dizzy or drowsy.

Drug-Drug Interaction: VONADAY TABLET may interact with antifungal drugs (amphotericin B), antivirals (foscarnet, ganciclovir, cidofovir), drugs treating obesity (orlistat), medicines used to treat chronic hepatitis B infection (adefovir), medicines treating chronic hepatitis C (ombitasvir, paritaprevir, ritonavir, dasabuvir), immunosuppressants (tacrolimus), antibiotics (amikacin, gentamicin, pentamidine, vancomycin), and fits medicines (carbamazepine).

Drug-Food Interaction: VONADAY TABLET may have interaction with St.John’s wort (herbal supplement used to treat depression). Avoid alcohol consumption while being treated with this medication.

Drug-Disease Interaction: VONADAY TABLET should not be used in patients with liver diseases, kidney diseases, mood disorders, heart diseases, hypercholesterolemia (high cholesterol levels in the body), bone disorders, lactic acidosis, and immune reconstitution syndrome.

• AMPHOTERICIN B
• FOSCARNET
• GANCICLOVIR
• CIDOFOVIR
• ORLISTAT
• ADEFOVIR
• OMBITASVIR
• PARITAPREVIR
• RITONAVIR
• DASABUVIR
• TACROLIMUS
• AMIKACIN
• GENTAMICIN
• PENTAMIDINE
• VANCOMYCIN
• CARBAMAZEPINE

• Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
• Never share personal items that can have body fluids or blood on them, such as razor blades or toothbrushes.
• Avoid sharing used needles, other injection or drug equipment.
• Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis as they can make you prone to HIV infection.
• Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark-green, yellow, orange, and red vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
• Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
• Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.
• Try to reduce emotional and physical stress by spending time with family or do whatever makes you happy.

Regular kidney and liver function tests, bone mineral density tests are recommended while taking VONADAY TABLET.

HIV infection: HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms, such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. HIV spreads through body fluids, such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it. However, it can be controlled by treating with antiretroviral drugs.