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Written By aquibnaseer ,
Reviewed By Sunny S , MBBS

Composition :

DISULFIRAM-500MG

Manufacturer/Marketer :

Kc Laboratories

Consume Type :

Oral

Return Policy :

Not Returnable

Therapeutic Class

[ANTI-ALCOHOLIC AGENT]

Country of origin

India

Manufacturer/Marketer address

2, Mahadev Darshan Compound, Opp. Sadanand Danait Hospital, Jeevan Vikas Kendra Marg Mumbai - 400069, Maharashtra.
Other Info - TYF0015

Author Details

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FAQs

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Safe if prescribed

Not recommended for alcoholism as Tyfusin 500 mg Tablet 10's and alcohol causes severe 'aldehyde reaction' causing life-threatening conditions.

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Pregnancy

Consult your doctor

Not enough data available but Tyfusin 500 mg Tablet 10's is not given in pregnant females unless recommended in a doctor.

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Breast Feeding

Consult your doctor

Not recommended as such, as not enough data is available. Breastfeeding mothers should consult a doctor before taking the Tyfusin 500 mg Tablet 10's.

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Driving

Safe if prescribed

Not recommended before driving. Tyfusin 500 mg Tablet 10's has been found to cause drowsiness in the patient. Hence, taking Tyfusin 500 mg Tablet 10's before driving or performing hazardous tasks is not recommended.

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Liver

Consult your doctor

Not recommended in liver patients. Tyfusin 500 mg Tablet 10's has been found to cause liver damage in patients & hence not recommended to be taken without doctors consultation.

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Kidney

Consult your doctor

Not recommended in kidney patients. Tyfusin 500 mg Tablet 10's should be taken by kidney patients only on doctors consultation.

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Children

Safe if prescribed

Strictly not recommended in children. it may result in neurological interactions resulting in harmful symptoms.

About Tyfusin 500 mg Tablet 10's

Tyfusin 500 mg Tablet 10's belongs to the class of medications called 'Antabuse' used to treat alcohol dependence or chronic alcoholism. Heavy long-term use of alcohol can cause addiction in an individual, thereby making changes in your brain. Long-term alcohol intake can severely damage your liver and cause liver cirrhosis or fatty liver syndrome.

Tyfusin 500 mg Tablet 10's contains 'Disulfiram', which works by blocking an enzyme that breakdown alcohol in our body. When a patient drinks alcohol, it is changed into acetaldehyde, Tyfusin 500 mg Tablet 10's blocks the enzyme that breaks down acetaldehyde. This results in a higher level of acetaldehyde in the blood, causing discomfort and physical reactions. Tyfusin 500 mg Tablet 10's can help alcohol-addicted people who have decided to quit alcohol drinking by deterring them from drinking again. So, it acts as a supportive agent in the treatment of alcoholism. 

Tyfusin 500 mg Tablet 10's should be taken as prescribed by your doctor, with or without a meal, to avoid stomach upset and at fixed daily intervals for best results. The common side effects of Tyfusin 500 mg Tablet 10's include drowsiness, tiredness, headache, acne, flushing (warmth, redness, or tingly feeling), sweating, increased thirst, swelling, rapid weight gain, nausea, severe vomiting, neck pain, throbbing headache, blurred vision, fast or pounding heartbeats or fluttering in your chest, confusion, weakness, spinning sensation, feeling unsteady, or and metallic/garlic-like taste in the mouth may occur as your body gets used to the medication. Everyone need not experience the above side effects. If the Tyfusin 500 mg Tablet 10's causes any serious case of discomfort, speak with a doctor.

Before starting Tyfusin 500 mg Tablet 10's, do not take Tyfusin 500 mg Tablet 10's if you have consumed alcohol within the past 12 hours. Do not consume alcohol while taking Tyfusin 500 mg Tablet 10's and at least up to 14 days after you stop taking Tyfusin 500 mg Tablet 10's. If your doctor prescribes, Tyfusin 500 mg Tablet 10's is safe to use during pregnancy and breastfeeding. Unpleasant effects may occur after taking minimal amounts of alcohol used in cooking or even if rubbed into the skin. Avoid alcohol-containing aftershave, perfumes/colognes, body lotions, vinegar and alcohol-containing mouthwash and hand sanitiser. Even exposure to alcohol-based hand sanitisers in some people can trigger a serious side effect response. Hence hand-washing with water and soap is recommended instead.

Uses of Tyfusin 500 mg Tablet 10's

Alcohol addiction

Medicinal Benefits Mweb

Key Benefits

Tyfusin 500 mg Tablet 10's contains 'Disulfiram', which belongs to 'Antabuse' used to treat alcohol dependence. It works by blocking an enzyme (acetaldehyde) that helps break alcohol in the body. Tyfusin 500 mg Tablet 10's helps alcohol-dependent people who have decided to quit alcohol drinking by deterring them from drinking again.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Tyfusin 500 mg Tablet 10's

Drug Warnings

Before taking the Tyfusin 500 mg Tablet 10's, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. Signs of an overdose of Tyfusin 500 mg Tablet 10's include feeling or being sick, stomach pain, diarrhoea, drowsiness, mental disorders, tiredness, rapid heartbeat, rapid breathing, high body temperature, low blood pressure, loss of muscle control, high blood sugar, changes in the blood (as seen in blood tests). Certain foods, liquid medicines, remedies, tonics, toiletries, perfumes, and sprays may contain enough alcohol to cause a disulfiram tablet-alcohol reaction. So avoid using any alcohol-containing drugs, hand wash, mouth wash or alcoholic beverages as it may lead to an 'aldehyde reaction'.

Drug-Drug Interactions

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DisulfiramAmprenavir
Critical

Drug-Drug Interactions

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How does the drug interact with Tyfusin 500 mg Tablet:
Coadministration of Tyfusin 500 mg Tablet with Metronidazole can increase the risk of side effects.

How to manage the interaction:
Taking Metronidazole and Tyfusin 500 mg Tablet together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, confusion, weakness, shortness of breath, or palpitations, contact your doctor. Do not discontinue any medications without consulting a doctor.
DisulfiramAmprenavir
Critical
How does the drug interact with Tyfusin 500 mg Tablet:
Coadministration of Amprenavir and Tyfusin 500 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Amprenavir and Tyfusin 500 mg Tablet together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like difficulty breathing, vomiting, sweating, palpitation, or dizziness, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DisulfiramBenznidazole
Critical
How does the drug interact with Tyfusin 500 mg Tablet:
Coadministration of Tyfusin 500 mg Tablet with Benznidazole can increase the risk of side effects.

How to manage the interaction:
Taking benznidazole and Tyfusin 500 mg Tablet together is advised as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, weakness, shortness of breath, or palpitations, contact your doctor immediately.
DisulfiramParaldehyde
Critical
How does the drug interact with Tyfusin 500 mg Tablet:
Coadministration of Paraldehyde and Tyfusin 500 mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Paraldehyde and Tyfusin 500 mg Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience palpitations, difficulty breathing, vomiting, sweating, chest pain, dizziness, or blurred vision contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Tyfusin 500 mg Tablet:
Coadministration of Tyfusin 500 mg Tablet and Leflunomide can increase the risk of liver problems.

How to manage the interaction:
There may be a possibility of interaction between Tyfusin 500 mg Tablet and Leflunomide, but it can be taken if prescribed by a doctor. If you have any of these symptoms fever, vomiting, stomach pain, dark urine, or yellowing of skin and eyes, contact your doctor right away. Do not discontinue any medications without consulting your doctor.
DisulfiramLomitapide
Severe
How does the drug interact with Tyfusin 500 mg Tablet:
Coadministration of Tyfusin 500 mg Tablet and Lomitapide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Tyfusin 500 mg Tablet and Lomitapide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
DisulfiramMipomersen
Severe
How does the drug interact with Tyfusin 500 mg Tablet:
Co-administration of Tyfusin 500 mg Tablet and Mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Tyfusin 500 mg Tablet and Mipomersen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, weakness, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tyfusin 500 mg Tablet:
Co-administration of Tyfusin 500 mg Tablet and Teriflunomide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Tyfusin 500 mg Tablet and Teriflunomide can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience dizziness, fever, joint pain, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tyfusin 500 mg Tablet:
Co-administration of Tyfusin 500 mg Tablet and Sertraline can increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Tyfusin 500 mg Tablet with Sertraline can lead to an interaction, it can be taken if advised by your doctor. However, consult the doctor immediately if you experience headache, vomiting, excessive sweating, or thirst. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tyfusin 500 mg Tablet:
Co-administration of Ritonavir with Tyfusin 500 mg Tablet can increase the risk or severity of side effects.

How to manage the interaction:
Co-administration of Tyfusin 500 mg Tablet with ritonavir can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor if you experience headaches, difficulty breathing, vomiting, excessive sweating, chest pain, palpitations, dizziness, or blurred vision. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

Habit Forming

No

Special Advise

  • Tyfusin 500 mg Tablet 10's may interfere with certain laboratory tests (including urine VMA/HVA tests), possibly causing false test results. It is a paramount priority for a patient to enlighten the laboratory personnel and all their doctors to know they use this drug.
  • Tyfusin 500 mg Tablet 10's should never be given to a patient when they are in a state of alcohol intoxication or without his full knowledge.
  • After you stop taking Tyfusin 500 mg Tablet 10's, do not drink alcohol for at least seven days as your body needs to start making the enzyme 'acetaldehyde' again. In case, drinking alcohol earlier than this may trigger an 'aldehyde reaction'.

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