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  1. Home
  2. Medicine

  3. Trofame XR Capsule 10's

Prescription drug
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Composition :

TROSPIUM-60MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

[ANTIMUSCARINIC AGENTS]

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - TRO0079

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:35 AM IST

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Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Safe if prescribed

You are recommended to avoid consumption of alcohol with Trofame XR Capsule as it may increase the risk of adverse effects of Trofame XR Capsule .

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Pregnancy

Consult your doctor

Trofame XR Capsule is a category C pregnancy drug and is given to pregnant women only if the doctor thinks benefits outweigh risks. However, please consult a doctor if you are pregnant.

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Breast Feeding

Consult your doctor

It is unknown whether Trofame XR Capsule is excreted in human milk. Therefore, please consult a doctor if you are breastfeeding. Trofame XR Capsule is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Safe if prescribed

Trofame XR Capsule may cause blurred vision in some people. Therefore, wait until your vision is clear before driving or operating heavy machinery.

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Liver

Consult your doctor

Take Trofame XR Capsule with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking Trofame XR Capsule if you have severe liver disease.

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Kidney

Consult your doctor

Take Trofame XR Capsule with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Safe if prescribed

Trofame XR Capsule is not recommended for children below 12 years as the safety and effectiveness were not established.

Reference

  1. https://www.medicines.org.uk/emc/files/pil.6643.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/021595s009lbl.pdf
  3. https://www.drugs.com/pregnancy/trospium.html

About Trofame XR Capsule

Trofame XR Capsule belongs to the class of drugs called antimuscarinics used to treat overactive bladder (OAB) symptoms. Overactive bladder is a problem with bladder function that causes a sudden urge to urinate. Overactive bladder symptoms include frequent urination, involuntary loss of urine, an urgent and uncontrollable need to urinate, or bedwetting.

Trofame XR Capsule contains Trospium which works by blocking muscarinic receptors on the surface of muscle cells and inhibits the action of acetylcholine (a chemical messenger) that causes contraction of the bladder muscle. Thereby, Trofame XR Capsule relaxes the involuntary muscle (detrusor) in the bladder wall and reduces unstable and involuntary contractions of the bladder, and increases the bladder's capacity to hold urine. Thus, it decreases the need to urinate.

Take Trofame XR Capsule as prescribed by your doctor. You are advised to take Trofame XR Capsule for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dry mouth, nausea, stomach pain, indigestion, or constipation. Most of these side effects of Trofame XR Capsule do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Trofame XR Capsule or any other medicines, please tell your doctor. Trofame XR Capsule is not recommended for children below 12 years as the safety and effectiveness were not established.  Please consult a doctor if you are pregnant or breastfeeding before taking Trofame XR Capsule . Do not consume alcohol with Trofame XR Capsule as it may increase the risk of adverse effects. You are recommended to drink plenty of water while taking Trofame XR Capsule to prevent dryness of the mouth. Drive only if your vision is clear after taking Trofame XR Capsule as it may cause blurred vision in some people for a short duration.

Uses of Trofame XR Capsule

Overactive bladder

Medicinal Benefits Mweb

Key Benefits

Trofame XR Capsule contains Trospium used to treat overactive bladder symptoms.  Trofame XR Capsule blocks muscarinic receptors on the muscle cells and inhibits the action of acetylcholine (a chemical messenger) that causes contraction of the bladder muscle. Thereby, Trofame XR Capsule relaxes the involuntary muscle (detrusor) in the bladder wall and reduces unstable and involuntary contractions of the bladder and increases bladder capacity to hold urine. Thus, it decreases the need to urinate.

Directions for Use

Take Trofame XR Capsule on empty stomach before a meal as prescribed by your doctor and swallow whole with a glass of water. Do not crush, chew or break it.

Side Effects of Trofame XR Capsule

  • Dry mouth
  • Nausea
  • Stomach pain
  • Indigestion
  • Constipation

Drug Warnings

If you are allergic to Trofame XR Capsule or any other medicines, please tell your doctor. If you have nerve damage, overactive thyroid,  hernia of the diaphragm with inflammation of the esophagus, liver, kidney, or heart problems, inform your doctor before taking Trofame XR Capsule . Trofame XR Capsule is not recommended for children below 12 years as the safety and effectiveness were not established.  Please consult a doctor if you are pregnant or breastfeeding before taking Trofame XR Capsule . Do not consume alcohol with Trofame XR Capsule as it may increase the risk of adverse effects. You are recommended to drink plenty of water while taking Trofame XR Capsule to prevent dryness of the mouth. Avoid taking Trofame XR Capsule if you have urinary retention, serious liver disorder, narrow-angle glaucoma, irregular heartbeats, myasthenia gravis (muscle weakness), and toxic megacolon (severe gastrointestinal condition). Drive only if your vision is clear after taking Trofame XR Capsule as it may cause blurred vision in some people for a short duration.

Drug-Drug Interactions

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TrospiumPotassium chloride
Critical
TrospiumPotassium citrate
Critical

Drug-Drug Interactions

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TrospiumPotassium chloride
Critical
How does the drug interact with Trofame XR Capsule:
Taking Trofame XR Capsule with Potassium chloride can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Trofame XR Capsule with Potassium chloride is not recommended as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
TrospiumPotassium citrate
Critical
How does the drug interact with Trofame XR Capsule:
Taking Potassium citrate and Trofame XR Capsule together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Trofame XR Capsule with Potassium citrate is not recommended as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
TrospiumZonisamide
Severe
How does the drug interact with Trofame XR Capsule:
Coadministration of Trofame XR Capsule with Zonisamide can increase the risk or severity of Zonisamide side effects like increased body temperature and decreased sweating.

How to manage the interaction:
Taking Trofame XR Capsule with Zonisamide together can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience changes in blood pressure, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
TrospiumTopiramate
Severe
How does the drug interact with Trofame XR Capsule:
Taking Trofame XR Capsule with Topiramate can cause increase in body temperature and decrease sweating.

How to manage the interaction:
Although taking Trofame XR Capsule and Topiramate together can evidently cause an interaction, but it should be taken if your doctor has suggested it. However, if you experience feeling sweating, feeling very tired, dizzy or lightheaded, or having trouble thinking clearly contact your doctor immediately. Do not stop using any medications without a doctor's advice.
TrospiumProcainamide
Severe
How does the drug interact with Trofame XR Capsule:
Using Trofame XR Capsule together with procainamide may increase the blood levels and effects of both the drugs.

How to manage the interaction:
There may be a possibility of interaction between Trofame XR Capsule and Procainamide, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • IMIPRAMINE
  • AMITRIPTYLINE
  • SALBUTAMOL
  • METOCLOPRAMIDE
  • COLESTIPOL
  • CHOLESTYRAMINE
  • MIRABEGRON
  • ACETAMINOPHEN
  • METOPROLOL
  • DIPHENHYDRAMINE

Habit Forming

No

Special Advise

Please consult a doctor if the condition persists or worsens after using Trofame XR Capsule for 1 month.

Diet & Lifestyle Advise

  • Pelvic floor exercises would help treat bladder spasms.
  • Avoid foods like sugars, carbonated beverages, tea, citrus fruits, tomatoes, spicy foods, chocolate and tea.
  • Limit fluid intake as excess fluid intake could cause an urge to urinate frequently.
  • Avoid drinking excess alcohol or caffeinated drinks as they can worsen the symptoms.
  • Maintain a healthy weight, and exercise regularly.
  • Avoid smoking and alcohol intake.
  • Take 6-8 glasses of liquids every day.
  • Avoid processed foods. Instead, choose whole, unprocessed foods.
  • Include fruits, vegetables, and fiber-rich food in your diet.

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