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Triplixam 4mg/1.25mg/5mg Tablet 10's

Triplixam 4mg/1.25mg/5mg Tablet 10's

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Written BySantoshini Reddy G,M Pharmacy
Reviewed ByHari Kumar,MBBS
Last Updated Aug 20, 2024 | 1:09 PM IST

About Triplixam 4mg/1.25mg/5mg Tablet 10's

Triplixam 4mg/1.25mg/5mg Tablet 10's belongs to the group of anti-hypertensive medicines used to treat high blood pressure (hypertension). High blood pressure is a condition in which the blood exerts increased pressure on the walls of blood vessels. Triplixam 4mg/1.25mg/5mg Tablet 10's helps lower the blood pressure, thereby reduces the chances of heart problems such as heart attack and stroke.  
 
Triplixam 4mg/1.25mg/5mg Tablet 10's contains Indapamide, Amlodipine, and Perindopril erbumine. Indapamide lowers blood pressure by increasing the amount of urine produced by the kidneys. Amlodipine relaxes the blood vessels, thereby improves blood flow. Perindopril erbumine widens the blood vessels, making it easier for the heart to pump blood through them. Together, Triplixam 4mg/1.25mg/5mg Tablet 10's helps treat hypertension.
 
You are advised to take Triplixam 4mg/1.25mg/5mg Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as oedema, headache, dizziness, flushing, and abdominal pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Triplixam 4mg/1.25mg/5mg Tablet 10's is not recommended during early pregnancy and should not be taken when more than 3 months pregnant as it may cause serious harm to the baby. Triplixam 4mg/1.25mg/5mg Tablet 10's is not recommended for breastfeeding mothers and children. Triplixam 4mg/1.25mg/5mg Tablet 10's may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

Uses of Triplixam 4mg/1.25mg/5mg Tablet 10's

Hypertension (high blood pressure).

Medicinal Benefits

Triplixam 4mg/1.25mg/5mg Tablet 10's is a combination of three drugs, namely: Indapamide, Amlodipine, and Perindopril erbumine. Triplixam 4mg/1.25mg/5mg Tablet 10's belongs to the group of anti-hypertensive medicines used to treat high blood pressure (hypertension). Triplixam 4mg/1.25mg/5mg Tablet 10's helps lower blood pressure, thereby reduces the chances of heart problems such as heart attack and stroke. Indapamide is a diuretic that lowers blood pressure by increasing the amount of urine produced by the kidneys. Amlodipine is a calcium channel blocker that relaxes the blood vessels, thereby improving blood flow. Perindopril erbumine is an angiotensin-converting enzyme inhibitor that widens the blood vessels; this makes it easier for the heart to pump blood through them. Together, Triplixam 4mg/1.25mg/5mg Tablet 10's helps treat hypertension.

Directions for Use

Take Triplixam 4mg/1.25mg/5mg Tablet 10's before a meal. Swallow Triplixam 4mg/1.25mg/5mg Tablet 10's as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Triplixam 4mg/1.25mg/5mg Tablet 10's

  • Oedema
  • Headache
  • Dizziness
  • Flushing
  • Tiredness
  • Weakness
  • Nausea
  • Vomiting

Drug Warnings

Do not take Triplixam 4mg/1.25mg/5mg Tablet 10's if you are allergic to any of its contents; if you have angioedema, severe liver/kidney problems, liver encephalopathy, severe water retention, low blood pressure, or low blood potassium. Inform your doctor if you have diabetes, heart problems, gout, parathyroid gland problems, heart failure, collagen disease, atherosclerosis (hardening of arteries), excess acid in the blood, liver/kidney problems, if you are on a low-salt diet, if you are taking lithium/potassium-sparing diuretics, low blood pressure in the brain, or if you are taking any other blood pressure-lowering medicines. Triplixam 4mg/1.25mg/5mg Tablet 10's is not recommended during early pregnancy and should not be taken when more than 3 months pregnant as it may cause serious harm to the baby. Triplixam 4mg/1.25mg/5mg Tablet 10's is not recommended for breastfeeding mothers and children. Triplixam 4mg/1.25mg/5mg Tablet 10's may cause dizziness, so drive with caution. Keep your doctor informed about your health condition and medications to rule out any interactions.

Therapeutic Class

ANTI- HYPERTENSIVES

Drug Interactions

Drug-Drug Interactions: Triplixam 4mg/1.25mg/5mg Tablet 10's may interact with anti-maniac drug (lithium), muscle relaxer (dantrolene), anti-cancer (estramustine), drugs used to treat heart failure (sacubitril+valsartan), potassium-sparing drugs (triamterene, amiloride), immunosuppressant (cyclosporin), anti-hypertensive (aliskiren).

Drug-Food Interactions: Avoid consuming grapefruit and grapefruit juice whilst taking Triplixam 4mg/1.25mg/5mg Tablet 10's as it might increase the blood levels of amlodipine; this can lead to an unpredictable increase in the blood pressure-lowering effect of Triplixam 4mg/1.25mg/5mg Tablet 10's. Inform your doctor if you are taking St. John's wort (a herbal supplement).

Drug-Disease Interactions: Inform your doctor if you have angioedema, severe liver/kidney problems, liver encephalopathy, severe water retention, low blood pressure, heart failure, or low blood potassium.

Drug-Drug Interactions Checker List

  • LITHIUM
  • DANTROLENE
  • ESTRAMUSTINE
  • SACUBITRIL+VALSARTAN
  • TRIAMTERENE
  • AMILORIDE
  • CICLOSPORIN
  • ALISKIREN

Habit Forming

No

Diet & Lifestyle Advise

  • You are advised to consume low salt and low-fat diet. 
  • Exercise regularly.
  • Eat a diet rich in whole grains, vegetables, and fruits.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight with proper diet and exercise.
  • Practice meditation or yoga as it helps in managing stress.

Special Advise

  • Regular monitoring of blood pressure levels, kidney function and electrolyte levels while taking Triplixam 4mg/1.25mg/5mg Tablet 10's is advised.
  • If you are due to have any surgery, inform the doctor that you are taking Triplixam 4mg/1.25mg/5mg Tablet 10's

Disease/Condition Glossary

High blood pressure (hypertension): It is a condition in which the blood exerts increased pressure on the walls of blood vessels leading to hypertension. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). High blood pressure also causes brain damage (stroke) and kidney failure. Symptoms of high blood pressure include headache, dizziness, nose bleed, changes in vision, chest pain, weakness and dyspnoea (shortness of breath). However, most of the time, the signs and symptoms of hypertension are none.

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