Trigli Sim-1 mg Tablet

Trigli Sim-1 mg Tablet is a combination of anti-diabetic drugs used to treat type 2 diabetes mellites. Type 2 diabetes is a chronic or lifelong condition that affects the way your body processes glucose. People with type 2 diabetes either do not produce enough insulin or if at all the insulin is produced, it is unable to perform its function in the body (insulin resistance). Due to this, the blood glucose level increases and causes symptoms such as frequent urination, increased thirst and increased hunger start. 

Trigli Sim-1 mg Tablet is a combination of three antidiabetic drugs: Glimepiride, Metformin and Voglibose. Glimepiride, which is a 'sulfonylurea', acts by increasing the amount of insulin released by the pancreas. Metformin, which is a 'biguanide', acts by lowering the glucose production in the liver, delaying glucose absorption from the intestines and increasing the body's response to insulin. Voglibose, which is an 'alpha-glucosidase inhibitor', prevents the breakdown of complex sugars into simple sugars such as glucose in the intestine. In a nutshell, the three medicines together prevent the blood glucose levels from rising to very high levels, thus keeping your diabetes under control.

Trigli Sim-1 mg Tablet should be taken with food to avoid an upset stomach. Based on your medical condition, your doctor will decide for how long you need to take Trigli Sim-1 mg Tablet . Trigli Sim-1 mg Tablet may cause certain common side effects such as hypoglycaemia (low blood glucose levels), taste change, nausea, diarrhoea, stomach pain, headache, upper respiratory symptoms. Most of these side effects do not require medical attention and will resolve gradually over time. However, if you experience these side effects persistently, consult your doctor.

Continue taking Trigli Sim-1 mg Tablet for as long as your doctor has advised. If you stop taking Trigli Sim-1 mg Tablet abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). Trigli Sim-1 mg Tablet should not be taken if you have type 1 diabetes mellitus, severe kidney or liver disease. Please inform your doctor if you have any type of heart disease, are planning to get pregnant or are breastfeeding.

Trigli Sim-1 mg Tablet contains Glimepiride, Metformin and Voglibose. Glimepiride, which is a 'sulfonylurea', acts by increasing the amount of insulin released by the pancreas. Metformin, which is a 'biguanide', acts by lowering the glucose production in the liver, delaying glucose absorption from the intestines and increasing the body's response to insulin. Voglibose, which is an 'alpha-glucosidase inhibitor' prevents the breakdown of complex sugars into simple sugars such as glucose in the intestine. Trigli Sim-1 mg Tablet prevents the blood glucose levels from rising to very high levels thus keeping your diabetes under control. Trigli Sim-1 mg Tablet also helps to prevent serious complications of diabetes such as kidney damage (Diabetic Nephropathy), blindness (Diabetic Retinopathy), loss of sensation in your hands and feet (Diabetic Neuropathy), Trigli Sim-1 mg Tablet also helps to reduce your chance of having a heart attack or stroke. Being a combination of three drugs, Trigli Sim-1 mg Tablet  reduces the need to take multiple pills and hence makes it easier to remember to take the drugs.

Some diabetic patients taking Trigli Sim-1 mg Tablet may develop a rare but serious condition called lactic acidosis. In this condition, there is too much lactic acid accumulated in the blood. So, your liver and kidney proper functioning is required for the elimination of excess lactic acid from the blood. You should not take Trigli Sim-1 mg Tablet if you have kidney disease, as measured by a blood test. Trigli Sim-1 mg Tablet may lower vitamin B12 levels, so try to have blood test annual blood and vitamin. Trigli Sim-1 mg Tablet when used with or without insulin has the tendency to extremely lower the blood sugar level. So, the doctor may lower the dose of insulin. Trigli Sim-1 mg Tablet may lower your thyroid-stimulating hormone (TSH), so an annual check-up of TSH is suggested.

• Keep taking the drug even if you think your blood sugar levels are under control. If you miss a dose, do not take a larger dose, consult your treating physician for advice. 
• Take short frequent meals, avoid prolonged fasting when taking this drug. Beware of symptoms of hypoglycaemia which include sweating, dizziness, palpitations, shivering, intense thirst, dry mouth, dry skin, frequent urination etc. Whenever you experience the above mentioned symptoms, immediately consume 5-6 candies or 3 glucose biscuits or 3 teaspoons of honey/sugar and also get in touch with your physician. Make sure to carry these with you at all times, especially for long travels. 
• It is always better that your physician knows about any underlying conditions like kidney disease or liver disease, prior heart attack, alcohol intake, etc before the doctor prescribes you this medicine.
• Avoid drinking alcohol while on this drug as it increases the risk of hypoglycaemia (decrease in blood sugar which might be fatal in some cases) and lactic acidosis (when the lactic acid increases in the body which impacts the functioning of various organs in the body).
• Try to quit smoking and reduce intake of carbohydrate rich food like potato, rice, mangoes, bread, sugar etc.
• Remember, lifestyle modifications are the most important step in controlling blood sugar levels.