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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Composition :

TOBRAMYCIN-300MG

Manufacturer/Marketer :

Fusion Health Care Pvt Ltd

Consume Type :

Inhalation

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

[ANTIBIOTICS]

Country of origin

India

Manufacturer/Marketer address

Fusion House, Plot No. 22, H.No 8-2-350/B, Road No. 3, Banjara Hills, Hyderabad, Telangana-500034
Other Info - TRE0372

FAQs

Disclaimer

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Alcohol

Safe if prescribed

It is unknown if alcohol affects Trespin Respules 5 ml. However, it is advisable to limit or avoid alcohol as a precautionary measure.

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Pregnancy

Consult your doctor

Trespin Respules 5 ml may not be recommended to be used in pregnancy. If you are pregnant, please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor as there is no substantial research yet on using Trespin Respules 5 ml in breastfeeding/nursing mothers.

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Driving

Safe if prescribed

Trespin Respules 5 ml may not affect your ability to drive, use, or operate machines.

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Liver

Consult your doctor

Limited information about the usage of Trespin Respules 5 ml in patients with liver disease is available. Please consult your physician. Your doctor will weigh the benefits and potential risks before prescribing Trespin Respules 5 ml.

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Kidney

Consult your doctor

Limited information about the usage of Trespin Respules 5 ml in patients with kidney disease is available. Please consult your physician. Your doctor will weigh the benefits and potential risks before prescribing Trespin Respules 5 ml.

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Children

Safe if prescribed

Children and adolescents aged six and up are eligible to use Trespin Respules 5 ml. Trespin Respules 5 ml should not be given to children under the age of six.

About Trespin Respules 5 ml

Trespin Respules 5 ml belongs to the class of aminoglycoside antibiotics. Trespin Respules 5 ml is used to treat chest infections caused by the bacteria Pseudomonas aeruginosa in cystic fibrosis patients aged six years and older. Pseudomonas aeruginosa is a type of bacteria that can cause lung or chest infections, especially in people who already have a lung disease (cystic fibrosis) or an issue with their immune system.

Trespin Respules 5 ml contains Tobramycin, an aminoglycoside antibiotic that fights the infection in your lungs by interfering with protein synthesis in Pseudomonas bacterial cell and helps you breathe better.

Use the Trespin Respules 5 ml as prescribed by your doctor. Sometimes, you may experience certain common side effects, such as runny or stuffy nose, sneezing, voice alteration (hoarseness), discolouration of the substance you cough up (sputum), worsening of lung function test results, feeling unwell, muscle pain and voice alteration with sore throat and difficulty swallowing (laryngitis). Most of these side effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not use Trespin Respules 5 ml if you are allergic to any of its components or other aminoglycoside antibiotics. Do not use the Trespin Respules 5 ml without consulting your doctor if you are pregnant or breastfeeding. Tell your doctor before prescribing Trespin Respules 5 ml if you have hearing problems, kidney problems, unusual difficulty breathing with wheezing or coughing, chest tightness, blood in the sputum, muscle weakness, and Parkinson's disease. Trespin Respules 5 ml is not recommended to be used in children under the age of six.

Uses of Trespin Respules 5 ml

Chest infections (Pseudomonas aeruginosa infection)

Medicinal Benefits Mweb

Key Benefits

Trespin Respules 5 ml contains Tobramycin, an aminoglycoside antibiotic that fights pulmonary infection by interfering with protein synthesis in Pseudomonas bacterial cells and allows you to breathe easier.

Directions for Use

Check the label for directions before using the Trespin Respules 5 ml. It is for inhalation only. Do not swallow the respules. Use it in the dose and for the duration advised by your doctor.

Side Effects of Trespin Respules 5 ml

  • Runny or stuffy nose, sneezing
  • Voice alteration (hoarseness)
  • Discolouration of the substance you cough up (sputum)
  • Worsening of lung function test results
  • Generally feeling unwell
  • Muscle pain
  • Voice alteration with a sore throat
  • Difficulty swallowing (laryngitis)

Drug Warnings

Do not use Trespin Respules 5 ml if you are allergic to any of the components or other aminoglycoside antibiotics (neomycin, paromomycin, kanamycin). Do not use the Trespin Respules 5 ml without consulting your doctor if you are pregnant or breastfeeding. Tell your doctor before prescribing Trespin Respules 5 ml if you have hearing problems, kidney problems, unusual difficulty breathing with wheezing or coughing, chest tightness, blood in the sputum, muscle weakness, and Parkinson's disease. Children and adolescents aged six and up are eligible to use Trespin Respules 5 ml. Trespin Respules 5 ml should not be given to children under the age of six. Before taking the Trespin Respules 5 ml, notify your doctor about your medical history and other medications you are now taking to rule out any potential adverse effects or interactions.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Trespin Respules 5 ml:
Coadministration of cidofovir with Trespin Respules 5 ml can cause kidney problems.

How to manage the interaction:
Taking Trespin Respules 5 ml with Cidofovir is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Trespin Respules 5 ml:
Co-administration of Trespin Respules 5 ml with torasemide increases the risk of toxicity.

How to manage the interaction:
Although taking Trespin Respules 5 ml and torasemide together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as blurred vision, dry mouth, dry skin, frequent urination, nausea, and stomach pain, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Trespin Respules 5 ml:
Coadministration of Trespin Respules 5 ml with Sirolimus can cause an increased risk or severity of kidney problems.

How to manage the interaction:
Although taking Sirolimus and Trespin Respules 5 ml together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Trespin Respules 5 ml:
Taking magnesium sulfate with Trespin Respules 5 ml can increase the risk of muscle weakness.

How to manage the interaction:
Although taking Magnesium sulfate and Trespin Respules 5 ml together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience symptoms such as muscle weakness and breathing difficulties consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Trespin Respules 5 ml:
Using Atracurium with Trespin Respules 5 ml can increase the risk of respiratory depression (breathing disorder).

How to manage the interaction:
Although there is a interaction between Trespin Respules 5 ml and Atracurium, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to your doctor.
How does the drug interact with Trespin Respules 5 ml:
Taking deferasirox with Trespin Respules 5 ml may increase the risk of kidney problems.

How to manage the interaction:
Taking Trespin Respules 5 ml with Deferasirox together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without talking to your doctor.
How does the drug interact with Trespin Respules 5 ml:
Using Botulinum toxin and Trespin Respules 5 ml together may increase the risk of side effects.

How to manage the interaction:
Although taking Botulinum toxin and Trespin Respules 5 ml can cause an interaction, it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience excessive muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Trespin Respules 5 ml:
Using Vecuronium with Trespin Respules 5 ml can increase the risk of respiratory depression(hypoventilation).

How to manage the interaction:
Co-administration of Trespin Respules 5 ml with Vecuronium can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Trespin Respules 5 ml:
Using Trespin Respules 5 ml together with everolimus can increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Everolimus and Trespin Respules 5 ml, you can take these medicines together if prescribed by a doctor. However, if you experience sudden weight gain, feeling out of breath, or having kidney problems. If you experience nausea, vomiting, loss of appetite, weight loss, swelling, muscle cramps, weakness, dizziness, confusion, or an irregular heartbeat contact a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Trespin Respules 5 ml:
Takin human immunoglobulin with Trespin Respules 5 ml may raise the risk of kidney problems.

How to manage the interaction:
Although taking Human immunoglobulin and Trespin Respules 5 ml together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • SALBUTAMOL
  • FUROSEMIDE
  • ETHACRYNIC ACID
  • MANNITOL

Habit Forming

No

Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Trespin Respules 5 ml to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains, like whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking too many calcium-enriched foods and drinks as it might affect the working of Trespin Respules 5 ml.
  • Avoid intake of alcoholic beverages with Trespin Respules 5 ml as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Trespin Respules 5 ml in fighting off infections.

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