Tocira-400 Infusion

Tocira-400 Infusion belongs to the class of 'immunosuppressants', primarily used to treat rheumatoid arthritis, ankylosing spondylitis, and giant cell arteritis (inflammation of the lining of your arteries) in adults. It is also used to treat rheumatoid arthritis in children, such as systemic juvenile idiopathic arthritis (SJIA) and polyarticular juvenile idiopathic arthritis (PJIA). Rheumatoid arthritis is an autoimmune disease in which the body's immune system attacks its own cells and cause joint pain with inflammation. Tocira-400 Infusion is currently being trialled to treat breathing complications in COVID-19 (Corona Virus Disease-19) patients. 

Tocira-400 Infusion consists of 'Tocilizumab' that belongs to the class of 'interleukin inhibitors.' It works by blocking the Interleukin-6 (IL-6), a substance released by the body that causes inflammation. Lately, Tocira-400 Infusion is also being used in COVID-19 infection to reduce the severity of inflammation and damage in the lungs. It is thought to decrease the cytokine storm, an excessive immune response that occurs in the lungs of a COVID-19 infected person.

Your doctor will decide the dose and duration based on the medical condition. Common side effects of Tocira-400 Infusion include runny nose, sinus pain, sore throat, increased blood pressure, pain and swelling at the injection site, and headache. These side effects are not familiar to everyone and vary individually. However, if the side effects are persistent, please reach out to your doctor.

Before starting Tocira-400 Infusion, inform your doctor if you have any liver, heart or kidney diseases, stomach and intestinal ulcers, multiple sclerosis (nerve and muscle disease), diabetes, weak immune system (HIV), hepatitis B, cancer, and active infections. Let your doctor know if you are pregnant or breastfeeding before starting Tocira-400 Infusion. Tocira-400 Infusion may cause dizziness, so drive only if you are alert and focused. Tocira-400 Infusion should not be given to children under two years of age as safety has not been established. Avoid consuming alcohol along with Tocira-400 Infusion as it could lead to increased dizziness and risk of liver damage. 

Tocira-400 Infusion treats pain, redness, and inflammation (swelling) in patients with rheumatoid arthritis, ankylosing spondylitis, and giant cell arteritis. It contains 'Tocilizumab,' an 'interleukin inhibitor.' It works by blocking the Interleukin-6 (IL-6), a substance released by the body that causes inflammation. Lately, Tocira-400 Infusion is also being used in COVID-19 infection to reduce breathing complications, the severity of inflammation, and damage in the lungs. It is used to decrease the cytokine storm, an excessive immune response that occurs in the lungs of a COVID-19 infected person. 

Inform your doctor if you have any liver, heart or kidney diseases, stomach and intestinal ulcers (diverticulitis), multiple sclerosis (nerve and muscle disease), low blood cell count, diabetes, weak immune system (HIV), hepatitis B, cancer, and active infections before starting Tocira-400 Infusion. Avoid close contact with people who have infections like chickenpox, measles, tuberculosis, and flu that can be easily spread. Thoroughly wash your hands to prevent the spread of infection. Do not take live vaccines while being treated with Tocira-400 Infusion to prevent any serious consequences. Tocira-400 Infusion may cause dizziness and drowsiness, so drive only if you are alert and focused. Avoid consuming alcohol along with Tocira-400 Infusion as it could lead to increased dizziness and risk of stomach bleeding/ulcers. Tocira-400 Infusion is not recommended in children younger than two years of age as safety and efficacy is not established. Store Tocira-400 Infusion at temperatures of 2°C to 8°C. Do not freeze the vial.

• It is advised to closely monitor the patient for infections like active tuberculosis during and after the treatment though the patient gets a negative tuberculin test.
• It is essential to inform your doctor if you have any active viral, bacterial, and fungal infections before starting Tocira-400 Infusion.