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  3. Tocira-400 Infusion 20 ml

48 Hrs returnable
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Tocira-400 Infusion 20 ml, Pack of 1 INFUSION
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Prescription drug

Whats That

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TOCILIZUMAB-400MG
PARENTERAL
Not Returnable
Apr-24
Prescription drug
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Country of origin

INDIA
Other Info - TOC0078

FAQs

Tocira-400 Infusion 20 ml contains Tocilizumab, an immunosuppressant. It blocks the action of Interleukin-6 (IL-6), a substance released by the body that causes inflammation. Thus, it helps in decreasing pain and inflammation in various diseases like rheumatoid arthritis, ankylosing spondylitis, and giant cell arteritis.
When a person is infected with the coronavirus, his/her immune system responds in such a way that it sends useful immune chemicals to the affected areas of the lungs to fight the infection. However, in some people, this release of immune chemicals is overactive, resulting in a cytokine storm, an excessive immune response in the lungs. This can further lead to severe breathing complications in an infected person. Tocira-400 Infusion 20 ml reduces this cytokine storm and further prevents the inflammation and damage in the lungs of a COVID-19 infected person.
Though Tocilizumab in Tocira-400 Infusion 20 ml is under the clinical trial stage of development by FDA for being used in COVID-19 infection, it is currently used to treat breathing complications for COVID-19 patients. It is known to show improvement in pneumonia during coronavirus infection.
Tocira-400 Infusion 20 ml is not recommended for every person infected with the coronavirus. Tocira-400 Infusion 20 ml has potential hazards and is only prescribed by doctors in patients with severe breathing difficulties and who have highly dropping saturation levels (blood oxygen level (SpO2)).
Tocira-400 Infusion 20 ml is to be carefully administered with caution in patients under doctor's supervision only since it can cause potential side effects like elevated liver enzymes, neutropenia (low levels of neutrophils), and thrombocytopenia (low levels of platelets). It can also cause serious viral infections like hepatitis B, bacterial infections including active tuberculosis, and fungal infections including candidiasis, aspergillosis, and pneumocystis.
Tocira-400 Infusion 20 ml affects your immune system and makes you more susceptible to infections. Hence, it is not recommended in people with active infections like tuberculosis, hepatitis B, abnormal liver enzymes, and platelet counts less than 50,000. Tocira-400 Infusion 20 ml can also increase the risk of developing cancers; hence it is essential to mention your doctor if you had a history of any cancer.
Even if there is no improvement after administering Tocira-400 Infusion 20 ml, your doctor may suggest an alternate course. Please note that Tocira-400 Infusion 20 ml does not reverse the damage caused due to coronavirus infection, but it will further prevent the inflammation of the lungs. It is also advised to medically examine for other lung and heart related dysfunctions even the patient suffers breathlessness after Tocira-400 Infusion 20 ml administration.
It is not recommended to get live vaccines like measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine while being treated with Tocira-400 Infusion 20 ml. This could lead to a severe infection. Please consult a doctor before you start Tocira-400 Infusion 20 ml if you are undergoing any vaccinations.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

You are recommended to avoid alcohol consumption if you are being treated with Tocira-400 Infusion 20 ml. Alcohol intake, along with Tocira-400 Infusion 20 ml, may cause increased dizziness and risk of stomach bleeding/ulcers.

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Pregnancy

Caution

Tocira-400 Infusion 20 ml is a pregnancy category C drug and is not recommended during pregnancy since animal studies showed harmful effects on the developing baby. Your doctor will prescribe Tocira-400 Infusion 20 ml only if the benefit outweighs the risk.

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Breast Feeding

Caution

It is not known if Tocira-400 Infusion 20 ml passes into the breastmilk when used by breastfeeding mother. Your doctor will prescribe Tocira-400 Infusion 20 ml only if the benefit outweighs the risk.

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Driving

Unsafe

Tocira-400 Infusion 20 ml may make you feel dizzy and sleepy. Do not drive or operate machinery if you experience dizziness or drowsiness.

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Liver

Caution

Please consult your doctor since Tocira-400 Infusion 20 ml should be used with caution in patients with liver impairment/liver disease. Dose adjustment may be needed in patients with liver impairment. However, Tocira-400 Infusion 20 ml is not recommended in patients with active liver diseases.

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Kidney

Caution

Please consult your doctor since Tocira-400 Infusion 20 ml should be used with caution in patients with kidney impairment/kidney disease. Dose adjustment may be required.

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Children

Caution

Tocira-400 Infusion 20 ml is not recommended in children younger than two years of age.

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/125276s092lbl.pdf
  2. https://www.webmd.com/drugs/2/drug-153516/tocilizumab-intravenous/details
  3. https://www.drugs.com/monograph/tocilizumab.html

About Tocira-400 Infusion 20 ml

Tocira-400 Infusion 20 ml belongs to the class of 'immunosuppressants', primarily used to treat rheumatoid arthritis, ankylosing spondylitis, and giant cell arteritis (inflammation of the lining of your arteries) in adults. It is also used to treat rheumatoid arthritis in children, such as systemic juvenile idiopathic arthritis (SJIA) and polyarticular juvenile idiopathic arthritis (PJIA). Rheumatoid arthritis is an autoimmune disease in which the body's immune system attacks its own cells and cause joint pain with inflammation. Tocira-400 Infusion 20 ml is currently being trialled to treat breathing complications in COVID-19 (Corona Virus Disease-19) patients. 

Tocira-400 Infusion 20 ml consists of 'Tocilizumab' that belongs to the class of 'interleukin inhibitors.' It works by blocking the Interleukin-6 (IL-6), a substance released by the body that causes inflammation. Lately, Tocira-400 Infusion 20 ml is also being used in COVID-19 infection to reduce the severity of inflammation and damage in the lungs. It is thought to decrease the cytokine storm, an excessive immune response that occurs in the lungs of a COVID-19 infected person.

Your doctor will decide the dose and duration based on the medical condition. Common side effects of Tocira-400 Infusion 20 ml include runny nose, sinus pain, sore throat, increased blood pressure, pain and swelling at the injection site, and headache. These side effects are not familiar to everyone and vary individually. However, if the side effects are persistent, please reach out to your doctor.

Before starting Tocira-400 Infusion 20 ml, inform your doctor if you have any liver, heart or kidney diseases, stomach and intestinal ulcers, multiple sclerosis (nerve and muscle disease), diabetes, weak immune system (HIV), hepatitis B, cancer, and active infections. Let your doctor know if you are pregnant or breastfeeding before starting Tocira-400 Infusion 20 ml. Tocira-400 Infusion 20 ml may cause dizziness, so drive only if you are alert and focused. Tocira-400 Infusion 20 ml should not be given to children under two years of age as safety has not been established. Avoid consuming alcohol along with Tocira-400 Infusion 20 ml as it could lead to increased dizziness and risk of liver damage. 

Uses of Tocira-400 Infusion 20 ml

Rheumatoid arthritis, Ankylosing spondylitis, and giant cell arteritis.

Medicinal Benefits Mweb

Medicinal Benefits

Tocira-400 Infusion 20 ml treats pain, redness, and inflammation (swelling) in patients with rheumatoid arthritis, ankylosing spondylitis, and giant cell arteritis. It contains 'Tocilizumab,' an 'interleukin inhibitor.' It works by blocking the Interleukin-6 (IL-6), a substance released by the body that causes inflammation. Lately, Tocira-400 Infusion 20 ml is also being used in COVID-19 infection to reduce breathing complications, the severity of inflammation, and damage in the lungs. It is used to decrease the cytokine storm, an excessive immune response that occurs in the lungs of a COVID-19 infected person. 

Directions for Use

Tocira-400 Infusion 20 ml will be administered by a healthcare professional. Do not self-administer.

Side Effects of Tocira-400 Infusion 20 ml

  • Runny nose
  • Sinus pain
  • Sore throat
  • Increased blood pressure
  • Pain and swelling at the injection site
  • Headache 

Drug Warnings

Inform your doctor if you have any liver, heart or kidney diseases, stomach and intestinal ulcers (diverticulitis), multiple sclerosis (nerve and muscle disease), low blood cell count, diabetes, weak immune system (HIV), hepatitis B, cancer, and active infections before starting Tocira-400 Infusion 20 ml. Avoid close contact with people who have infections like chickenpox, measles, tuberculosis, and flu that can be easily spread. Thoroughly wash your hands to prevent the spread of infection. Do not take live vaccines while being treated with Tocira-400 Infusion 20 ml to prevent any serious consequences. Tocira-400 Infusion 20 ml may cause dizziness and drowsiness, so drive only if you are alert and focused. Avoid consuming alcohol along with Tocira-400 Infusion 20 ml as it could lead to increased dizziness and risk of stomach bleeding/ulcers. Tocira-400 Infusion 20 ml is not recommended in children younger than two years of age as safety and efficacy is not established. Store Tocira-400 Infusion 20 ml at temperatures of 2°C to 8°C. Do not freeze the vial.

Drug-Drug Interactions

verifiedApollotooltip
TocilizumabClozapine
Severe
TocilizumabBaricitinib
Severe

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Drug Interactions Checker List

  • INFLIXIMAB
  • ADALIMUMAB
  • ABATACEPT
  • ETANERCEPT
  • WARFARIN
  • ATORVASTATIN
  • LOVASTATIN
  • SIMVASTATIN
  • OMEPRAZOLE
  • DEXTROMETHORPHAN
  • CERTOLIZUMAB
  • GOLIMUMAB
  • ANAKINRA

Habit Forming

No

Special Advise

  • It is advised to closely monitor the patient for infections like active tuberculosis during and after the treatment though the patient gets a negative tuberculin test.
  • It is essential to inform your doctor if you have any active viral, bacterial, and fungal infections before starting Tocira-400 Infusion 20 ml.

Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching that is less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well and get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated; drink plenty of water.