Sefpine TZ 2250mg Injection

Sefpine TZ 2250mg Injection belongs to the class of medications called ‘antibiotics’ used to treat bacterial infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick. Symptoms of bacterial infection vary depending on the organ affected by bacteria.

Sefpine TZ 2250mg Injection is a combination of two medicines: Cefepime and Tazobactam. Cefepime is a cephalosporin antibiotic. It has bactericidal action (kills bacteria). It works by preventing the formation of the cell wall (the outer protective layer of bacteria, which is essential for its survival) by preventing protein synthesis. Tazobactam is a beta-lactamase inhibitor. It can improve the spectrum of antibacterial action by inhibiting the action of beta-lactamase. Beta-lactamase is an enzyme produced by bacteria that can destroy antibiotics (cefotaxime). Sefpine TZ 2250mg Injection is only used to treat bacterial infections and is not recommended for viral infections.

Sefpine TZ 2250mg Injection will be administered by a healthcare professional; do not self-administer. The common side effects of Sefpine TZ 2250mg Injection are pain and swelling at the injection site and skin rash. These side effects are usually mild and temporary. However, if any of these side effects persist or get worse, inform your doctor immediately.

It is not recommended to take Sefpine TZ 2250mg Injection if you are allergic to penicillin, any cephalosporin antibiotic, or its contents. Before taking Sefpine TZ 2250mg Injection, inform your doctor if you have kidney problems, diabetes, gastrointestinal problems, especially colitis (inflammation of the large intestine), or use other antibiotics. Do not discontinue or abruptly stop using Sefpine TZ 2250mg Injection as it may lead to antibiotic resistance (bacteria become resistant to antibiotics). This medicine is not recommended in children aged less than two years. Sefpine TZ 2250mg Injection should be used with caution in pregnant women, breastfeeding mothers and elderly people. Sefpine TZ 2250mg Injection may interact with alcohol. Sefpine TZ 2250mg Injection may not affect your ability to drive.

Sefpine TZ 2250mg Injection contains Cefepime and Tazobactam. Cefepime is a cephalosporin antibiotic, whereas Tazobactam is a beta-lactamase inhibitor. Sefpine TZ 2250mg Injection has broad-spectrum activity and is effective against both gram-positive and gram-negative bacteria. It makes the drug effective in multiple moderate to severe bacterial infections such as urinary tract infections (UTI), skin infections, intra-abdominal infections, lower respiratory tract (lung) infections such pneumonia (inflammation of the air sacs present in lungs) and bronchitis (inflammation of the bronchi), septicemia (including infections of the bloodstream), and empiric treatment in febrile neutropenic patients (development of fever in patients with low neutrophil count).

Sefpine TZ 2250mg Injection should be used with caution in patients with kidney impairment. There is a risk of serious adverse events such as confusion, hallucinations, stupor (a state of near-unconsciousness), and seizures (fits). Sefpine TZ 2250mg Injection may cause Clostridium difficile-associated diarrhoea (CDAD), ranging from mild diarrhea to fatal colitis (inflammation of the large intestine). If CDAD is suspected or confirmed, the doctor may discontinue therapy and advise appropriate fluid and electrolyte management, protein supplementation, and antibiotic therapy to treat CDAD. A Sefpine TZ 2250mg Injection may cause positive direct Coomb’s test, which indicates antibodies against red blood cells. So, it is necessary to let your doctor know that you are taking this medicine before undergoing laboratory tests. Do not discontinue or abruptly stop the medication as it may lead to antibiotic resistance, a condition in which bacteria become resistant to antibiotics. Sefpine TZ 2250mg Injection may cause superinfection (additional infection caused by other microbes) on prolonged use.

• Sefpine TZ 2250mg Injection may cause positive Coomb’s test, increase liver enzymes, alter red blood cell count, decrease phosphorus and cause abnormal prothrombin time (PT) and partial thromboplastin time (PTT) (abnormal PT and PTT indicate abnormal blood clotting). So, it is necessary to let your doctor know that you are taking Sefpine TZ 2250mg Injection before undergoing laboratory tests.
• If you are taking aminoglycoside antibiotics such as streptomycin and gentamicin, your kidney function should be regularly monitored.