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  3. RCINEX R CIN + INH 450MG CAPSULE

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

[ANTI- TUBERCULOSIS]

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - RCI0006

Author Details

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Safe if prescribed

Avoid alcohol consumption while taking RCINEX R CIN + INH 450MG CAPSULE as it could lead to increased drowsiness, dizziness and liver damage.

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Pregnancy

Consult your doctor

Please consult your doctor if you are pregnant, your doctor will prescribe RCINEX R CIN + INH 450MG CAPSULE only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

RCINEX R CIN + INH 450MG CAPSULE passes into breast milk. Do not breastfeed while taking RCINEX R CIN + INH 450MG CAPSULE.

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Driving

Safe if prescribed

RCINEX R CIN + INH 450MG CAPSULE may cause dizziness, drowsiness, numbness and tingling sensation in hands and feet. Do not drive or operate machinery if you experience these symptoms.

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Liver

Consult your doctor

Dose adjustment may be needed. Please consult your doctor before taking RCINEX R CIN + INH 450MG CAPSULE if you have liver impairment/liver disease.

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Kidney

Consult your doctor

Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking RCINEX R CIN + INH 450MG CAPSULE.

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Children

Safe if prescribed

Please consult your doctor. Your doctor may suggest suitable dose and dosage form based on your child's age, body weight and medical condition. Kid tablets could be used in children if prescribed by the doctor.

About RCINEX R CIN + INH 450MG CAPSULE

RCINEX R CIN + INH 450MG CAPSULE belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat and prevent tuberculosis. Tuberculosis is an infectious disease that mainly affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow.

RCINEX R CIN + INH 450MG CAPSULE is a combination of two anti-tuberculosis drugs, namely: Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, RCINEX R CIN + INH 450MG CAPSULE kills Mycobacterium tuberculosis which causes TB (tuberculosis).

In some cases, you may experience certain common side-effects such as drowsiness, dizziness, headache, weakness, muscle pain, heartburn, diarrhoea, gas, and numbness or tingling sensation. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor before taking RCINEX R CIN + INH 450MG CAPSULE if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking RCINEX R CIN + INH 450MG CAPSULE as it passes into breast milk. RCINEX R CIN + INH 450MG CAPSULE may cause dizziness, and vision problems, so drive only if you are alert. Avoid alcohol consumption while taking RCINEX R CIN + INH 450MG CAPSULE as it could lead to increased drowsiness, dizziness and liver damage.

Uses of RCINEX R CIN + INH 450MG CAPSULE

Tuberculosis.

Medicinal Benefits Mweb

Key Benefits

RCINEX R CIN + INH 450MG CAPSULE is a combination of two anti-tuberculosis drugs, namely: Rifampicin, and Isoniazid. Rifampicin inhibits DNA-dependent RNA polymerase activity in the bacteria. Isoniazid inhibits the biosynthesis of mycolic acid, which is the major component of the cell wall. Together, RCINEX R CIN + INH 450MG CAPSULE kills Mycobacterium tuberculosis which causes TB (tuberculosis).

Directions for Use

Take RCINEX R CIN + INH 450MG CAPSULE 30 minutes before food or 2 hours after food. Swallow RCINEX R CIN + INH 450MG CAPSULE as a whole; do not crush or chew it.

Side Effects of RCINEX R CIN + INH 450MG CAPSULE

  • Drowsiness
  • Dizziness
  • Headache
  • Weakness
  • Muscle pain 
  • Heartburn 
  • Diarrhoea
  • Gas
  • Numbness 

Drug Warnings

Do not take RCINEX R CIN + INH 450MG CAPSULE if you are allergic to any of its contents; if you have jaundice, or if you are taking HIV medicines (saquinavir or ritonavir). Before starting RCINEX R CIN + INH 450MG CAPSULE, please inform your doctor if you have diabetes, epilepsy, gout, mental health problems, HIV infection, malnutrition, peripheral neuropathy, porphyria, bleeding problems, kidney or liver problems. Consult your doctor before taking RCINEX R CIN + INH 450MG CAPSULE if you are pregnant or planning for pregnancy. Avoid breastfeeding while taking RCINEX R CIN + INH 450MG CAPSULE as it passes into breast milk. RCINEX R CIN + INH 450MG CAPSULE may cause dizziness, and drowsiness, so drive only if you are alert. Avoid alcohol consumption while taking RCINEX R CIN + INH 450MG CAPSULE as it could lead to increased drowsiness, dizziness and liver damage.

Drug-Drug Interactions

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RifampicinSaquinavir
Critical

Drug-Drug Interactions

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RifampicinSaquinavir
Critical
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking saquinavir with Rcinex R Cin + Inh 450mg Capsule can increase the risk or severity of side effects.

How to manage the interaction:
Although there is an interaction between pyrazinamide and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience fever, stomach pain, less desire to eat, nausea, yellowing of the skin or eyes, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
When Indinavir is taken with Rcinex R Cin + Inh 450mg Capsule, it can reduce the blood levels and effects of Indinavir.

How to manage the interaction:
Although there is an interaction between indinavir and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking pirfenidone with Rcinex R Cin + Inh 450mg Capsule can reduce the levels and effects of pirfenidone

How to manage the interaction:
Although there is an interaction between pirfenidone and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking darunavir with Rcinex R Cin + Inh 450mg Capsule can decrease the blood levels of darunavir, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between darunavir and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking Voriconazole with Rcinex R Cin + Inh 450mg Capsule can increase blood level of Voriconazole.

How to manage the interaction:
Although there is an interaction between Voriconazole with Rcinex R Cin + Inh 450mg Capsule, it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
When ranolazine is taken with Rcinex R Cin + Inh 450mg Capsule, it can reduce the blood levels and effects of ranolazine.

How to manage the interaction:
Although there is an interaction between ranolazine and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
When Rcinex R Cin + Inh 450mg Capsule is taken with Regorafenib, it can increase the levels of Regorafenib leading to side effects.

How to manage the interaction:
Taking Regorafenib with Rcinex R Cin + Inh 450mg Capsule is not recommended, it taken can be taken if prescribed by the doctor.
IsoniazidLomitapide
Critical
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
When Lomitapide is taken with Rcinex R Cin + Inh 450mg Capsule, Rcinex R Cin + Inh 450mg Capsule may increase the blood levels of lomitapide which leads to side effects.

How to manage the interaction:
Taking Rcinex R Cin + Inh 450mg Capsule with Lomitapide is not recommended but can be taken if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor.
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
When Lovastatin is taken with Rcinex R Cin + Inh 450mg Capsule, can increase the risk of myopathy (muscles problems), including rhabdomyolysis (a condition that causes your muscles to break down, which leads to muscle death).

How to manage the interaction:
Taking Rcinex R Cin + Inh 450mg Capsule with Lovastatin is not recommended but can be taken if a doctor has prescribed it.
RifampicinBedaquiline
Severe
How does the drug interact with Rcinex R Cin + Inh 450mg Capsule:
Taking bedaquiline with Rcinex R Cin + Inh 450mg Capsule can decrease the blood levels of bedaquiline, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between bedaquiline and Rcinex R Cin + Inh 450mg Capsule, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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ISONIAZID-300MG+RIFAMPICIN-450MGTyramine-containing food
Moderate

Drug-Food Interactions

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ISONIAZID-300MG+RIFAMPICIN-450MGTyramine-containing food
Moderate
Common Foods to Avoid:
Pepperoni, Miso Soup, Natto, Ricotta, Salami, Shoyu, Shrimp, Stilton Cheese, Swiss Cheese, Tamari, Tempeh, Fish, Farm Cheese, Fava Beans, Fermented Seafood, Fermented Tofu, Gorgonzola Cheese, Chicken Liver, Chocolates, Cottage Cheese, Cream Cheese, Dried Sausage, Dry-Type Summer Sausages, Cheddar Cheese, Cashews, Camembert, Beef Liver, American Cheese, Almonds, Avocado

How to manage the interaction:
Coadministration of Rcinex R Cin + Inh 450mg Capsule with foods containing tyramine increases the risk of side effects such as headache, sweating, diarrhea, nausea, vomiting, fast heartbeats, difficulty breathing, and low blood pressure. Avoid foods containing tyramine while being treated with Rcinex R Cin + Inh 450mg Capsule , as it can lead to side effects.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • SAQUINAVIR
  • RITONAVIR
  • ACETAMINOPHEN
  • HYDROCODONE
  • DULOXETINE
  • BUPROPION
  • DILTIAZEM
  • ETHAMBUTOL
  • PYRAZINAMIDE
  • CHOLECALCIFEROL
  • ERGOCALCIFEROL

Habit Forming

No

Special Advise

  • RCINEX R CIN + INH 450MG CAPSULE may affect test results of some blood tests such as tests for folate, vitamin B12, and liver function. Inform the person doing the tests that you are taking RCINEX R CIN + INH 450MG CAPSULE.
  • Your doctor may advise you to get regular liver tests while taking RCINEX R CIN + INH 450MG CAPSULE to check how your liver is functioning.

Diet & Lifestyle Advise

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Foods rich in vitamin C such as kiwi, broccoli, and bell pepper helps in improving the immune system. 
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help in providing relief from cough.
  • Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
  • Quit smoking and avoid alcohol consumption.

Have a query?