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48 Hrs returnable
COD available

Online payment accepted

Prescription drug

Whats That

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DABRAFENIB-75MG
ORAL
Not Returnable
Apr-24
Prescription drug
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Country of origin

India
Other Info - RAF0046

FAQs

Rafinlar 75 mg Capsule 28's contains Dabrafenib, which works by inhibiting the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells.
It is advised not to miss any dose of medicine. If you miss it, take the medicine as soon as you remember. However, if it is time for your next dose, avoid taking the missed dose and do not double the dose.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Consult your doctor

It is unknown whether Rafinlar 75 mg Capsule 28's interacts with alcohol. Consult your doctor.

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Pregnancy

Unsafe

Rafinlar 75 mg Capsule 28's is not recommended for use in pregnancy as it may cause embryo-fetal toxicity and harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Rafinlar 75 mg Capsule 28's. You should not become pregnant while you are taking Rafinlar 75 mg Capsule 28's for at least two weeks from the last dose of Rafinlar 75 mg Capsule 28's. Using effective birth control methods while on treatment with Rafinlar 75 mg Capsule 28's is suggested.

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Breast Feeding

Unsafe

Inform your doctor if you are intending to breastfeed. Breastfeeding should be avoided while getting Rafinlar 75 mg Capsule 28's and for at least two weeks from the final dosage of administration.

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Driving

Unsafe

Rafinlar 75 mg Capsule 28's may cause visual disturbances such as loss of vision or blurred vision in some patients. Hence, avoid driving and operating machines until you are completely alert.

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Liver

Caution

If you have a pre-existing or a history of liver problems, tell your doctor before taking this medicine.

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Kidney

Caution

If you have a pre-existing or a history of kidney problems, tell your doctor before taking this medicine.

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Children

Caution

Rafinlar 75 mg Capsule 28's is not recommended for use in children below six years of age, as the safety and efficacy have not been established. In children above six years, it is used in the treatment of unresectable or metastatic solid tumours with BRAF V600E mutation when prescribed by your doctor.

About Rafinlar 75 mg Capsule 28's

Rafinlar 75 mg Capsule 28's is an anti-cancer medicine used in the treatment of various types of cancers. Cancer is a disease caused by the abnormal growth of cells that divide uncontrollably. This medicine is used as a single agent in treating patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutation. It is also used along with trametinib in treating anaplastic thyroid cancer, non-small cell lung cancer with BRAF V600E mutation, and unresectable or metastatic solid tumours with BRAF V600E mutation.

Rafinlar 75 mg Capsule 28's contains Dabrafenib, which belongs to the class of medicines known as kinase inhibitors. It works by inhibiting the action of an enzyme (tyrosine kinase) and thus stops the abnormal growth of cancer cells.

Rafinlar 75 mg Capsule 28's may cause certain side effects such as diarrhoea, decreased appetite, nausea, vomiting, tiredness, itching, rash, headache, fever, acne, increased blood pressure, cough, and abdominal pain. Inform your doctor if any of these side effects bother you. Rafinlar 75 mg Capsule 28's should be taken as prescribed by your doctor. Do not take more than the recommended dose of medicine.

If you are allergic to Rafinlar 75 mg Capsule 28's or its components, inform your doctor. Before taking Rafinlar 75 mg Capsule 28's, inform your doctor if you have/had liver or kidney disease, calcium deficiency, heart problems, increased blood pressure, seizures, bleeding disorders, vision problems, and a history of blood clots. This medicine is known to cause embryo-fetal toxicity. It is not recommended for use in pregnancy and breastfeeding. 

Uses of Rafinlar 75 mg Capsule 28's

Metastatic melanoma, Anaplastic thyroid cancer, Non-small cell lung cancer, Metastatic solid tumors.

Medicinal Benefits Mweb

Medicinal Benefits

Rafinlar 75 mg Capsule 28's contains Dabrafenib, which is used in treating different types of cancer. It works by stopping the action of a tyrosine kinase enzyme that causes the multiplication of cancerous cells. This helps stop the abnormal growth of cancer cells and thus reduce the further spread to other parts of the body. It also decreases the blood supply to cancer tumors to slow down the growth of the tumor.  In this way, Rafinlar 75 mg Capsule 28's stops the body's production, spread and growth of cancerous cells.

Directions for Use

Take Rafinlar 75 mg Capsule 28's as prescribed by the doctor. It should be taken at least one hour before or 2 hours after meals. Swallow it as a whole with a glass of water. Do not crush, break, or chew it. Your doctor may suggest you take Rafinlar 75 mg Capsule 28's twice daily in a 12-hour interval. It is advised not to take more than the recommended dose of medicine.

Side Effects of Rafinlar 75 mg Capsule 28's

  • Nausea
  • Vomiting
  • Diarrhoea
  • Loss of appetite
  • Tiredness
  • Muscle/joint pain
  • Dizziness
  • Weakness
  • Warts
  • Cough
  • Headache
  • Itching
  • Rash
  • Abdominal pain
  • Vision problem
  • Increased blood pressure
  • Acne
  • Infection around finger and toenails

Drug Warnings

To treat your condition effectually, continue taking Rafinlar 75 mg Capsule 28's for the period that your doctor has prescribed. Avoid taking Rafinlar 75 mg Capsule 28's if you are allergic to it or any other components present in it. Caution should be exercised if you have/had liver or kidney disease, heart disease, blood or bleeding disorders, diabetes, eye problems, or gastrointestinal disorders. Inform your doctor if you are pregnant or are planning to become pregnant before starting the treatment, as this medicine is known to cause embryo-fetal toxicity. Breastfeeding should be discontinued in nursing mothers during the treatment as it passes into breast milk and may cause a possible risk to the infant. Avoid driving and operating machines, as this medicine may cause visual disturbances. This medicine is not recommended for use in children below six years of age as the safety and efficacy are not established. Rafinlar 75 mg Capsule 28's may cause hypertension, thrombotic events, hemorrhagic events, cardiomyopathy, severe skin reactions, Glucose-6-phosphate Dehydrogenase Deficiency (G6PD), uveitis, tumor promotion in BRAF wild-type tumors, the occurrence of new malignancies, and hyperglycemia in some patients. Hence, inform your doctor about your complete medication and medical history before taking Rafinlar 75 mg Capsule 28's.

Drug-Drug Interactions

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DabrafenibLevonorgestrel
Severe
DabrafenibRanolazine
Severe

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Drug Interactions Checker List

  • ITRACONAZOLE
  • KETOCONAZOLE
  • FLUCONAZOLE
  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • DILTIAZEM
  • WARFARIN
  • VERAPAMIL
  • RITONAVIR

Habit Forming

No

Special Advise

  • Using contraceptive pills while using Rafinlar 75 mg Capsule 28's to prevent pregnancy is advised.
  • Thyroid function and symptoms of anemia will be monitored during treatment to avoid any life-threatening side effects.
  • Seek medical attention immediately if you have swelling in your lower legs, fast heartbeats, or trouble breathing, as it may be a sign of a heart problem.
  • An ECG and ECHO will be performed frequently to check for left ventricular ejection fraction (LVEF) during the treatment course.

Diet & Lifestyle Advise

  • Eat food rich in antioxidants such as berries, spinach, etc.
  • Foods containing fibre help in better digestion. These include beans, peas, lentils, whole grains, nuts, and seeds.
  • Physical activity helps strengthen muscles, reduces fatigue, helps in weight loss, and gives strength. Gentle activities like 20-30 minutes of walking or swimming would be helpful.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Getting adequate sleep as resting helps improve your health and mental ability and improves attention.
  • Avoid smoking and alcohol consumption.
  • Maintain a healthy weight.

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