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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Composition :

ISONIAZID-300MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

Therapeutic Class

[ANTI- TUBERCULOSIS]

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country of Origin: India
Other Info - PYZ0004

Author Details

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Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Safe if prescribed

Avoid alcohol consumption while on treatment with PYZINA KID TABLET as it may increase the risk of liver damage. Please consult your doctor in case of any concerns.

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Pregnancy

Consult your doctor

If you are pregnant, consult your doctor before taking PYZINA KID TABLET. Your doctor may prescribe this medicine if only the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

PYZINA KID TABLET is excreted in breast milk in low quantities. If you are breastfeeding, consult your doctor before taking PYZINA KID TABLET. Your doctor may prescribe this medicine if only the benefits outweigh the risks.

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Driving

Safe if prescribed

PYZINA KID TABLET may cause mental health problems, fits or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience any of these symptoms after taking PYZINA KID TABLET.

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Liver

Consult your doctor

Take PYZINA KID TABLET with caution, especially if you have a history of Liver diseases/conditions. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Consult your doctor

Take PYZINA KID TABLET with caution, especially if you have a history of Kidney diseases/conditions. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Safe if prescribed

PYZINA KID TABLET is not recommended for children below 3 months of age. However, in children above 3 months, PYZINA KID TABLET should be used under medical supervision.

About PYZINA KID TABLET

PYZINA KID TABLET belongs to the group of medicines called anti-tubercular agents primarily used to treat and prevent tuberculosis (TB). Tuberculosis is an infectious bacterial disease that mainly affects the lungs, but it can also spread to other body parts such as the kidneys, brain, spine, and bone marrow. PYZINA KID TABLET does not work against infections caused by the virus.

PYZINA KID TABLET contains isoniazid, an antibiotic that works by preventing bacteria from producing mycolic acids, an enzyme required for cell wall formation (protective coating). As a result of the disturbance in their metabolism, bacteria that lack a cell wall die and burst. Thus, PYZINA KID TABLET inhibits the spread of infection by acting against the bacteria Mycobacterium tuberculosis, which causes tuberculosis.

Take PYZINA KID TABLET as prescribed. Use PYZINA KID TABLET for as long as your doctor has prescribed it based on your medical condition. In some cases, you may experience fever, dizziness, nausea, stomach upset, loss of appetite, constipation, tiredness, numbness, or tingling in the feet or hands as side effects of PYZINA KID TABLET. Most of these side effects do not require medical attention and gradually resolve over time. However, if any of these side effects persist or worsen, please consult your doctor.

If you are allergic to PYZINA KID TABLET or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking PYZINA KID TABLET. PYZINA KID TABLET may cause mental health problems, fits, or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience any of these symptoms after taking PYZINA KID TABLET.  Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer while on treatment with PYZINA KID TABLET as they might interact with this medicine. If you have fits, diabetes, HIV infection, malnutrition, kidney or liver problems, or have suffered from psychosis (mental disturbances), inform your doctor before taking PYZINA KID TABLET.

Uses of PYZINA KID TABLET

Tuberculosis (TB)

Medicinal Benefits Mweb

Key Benefits

PYZINA KID TABLET contains isoniazid, an antibiotic used to treat and prevent tuberculosis. PYZINA KID TABLET prevents bacteria from producing mycolic acids, which are required for the formation of cell walls (protective coating). Additionally, PYZINA KID TABLET may combine with an enzyme that interferes with bacterial cell metabolism. Bacteria die as a result of the disruption in their metabolism and the lack of a cell wall. As a result, it kills Mycobacterium tuberculosis bacteria that causes tuberculosis (TB) and eliminates the infection.

Directions for Use

Take PYZINA KID TABLET on an empty stomach at least one hour before or two hours after a meal or as advised by your doctor. Do not take it with food. Tablet: Swallow it as a whole with a glass of water. Do not crush, break or chew it. Syrup: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Side Effects of PYZINA KID TABLET

  • Fever
  • Dizziness
  • Nausea
  • Stomach upset
  • Loss of appetite
  • Constipation
  • Tiredness
  • Numbness or tingling in the feet or hands

Drug Warnings

If you are known to be allergic to PYZINA KID TABLET, please inform your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking PYZINA KID TABLET. PYZINA KID TABLET may cause mental health problems, fits or optic neuritis (swelling of the optic nerve that may cause vision loss) in some people. Therefore, avoid driving if you experience any of these symptoms after taking PYZINA KID TABLET. Avoid foods and drinks containing a high level of tyramine, such as fermented foods, cheese, cured meat, soya, tuna, salmon, mackerel, wine, and beer, while taking PYZINA KID TABLET as they might cause drug-food interaction. Avoid alcohol consumption with PYZINA KID TABLET as it may cause liver damage. If you have fits, diabetes, HIV infection, malnutrition, kidney or liver problems or have suffered from psychosis (mental disturbances), inform your doctor before taking PYZINA KID TABLET.

Drug-Drug Interactions

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PyrazinamideLomitapide
Severe

Drug-Drug Interactions

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PyrazinamideLomitapide
Severe
How does the drug interact with Pyzina Kid Tablet:
Co-administration of Lomitapide with Pyzina Kid Tablet may increase in the risk or severity of liver problems.

How to manage the interaction:
Although taking Lomitapide and Pyzina Kid Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor immediately: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, or bleeding. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Pyzina Kid Tablet:
Co-administration of Ketoconazole with Pyzina Kid Tablet may increase the risk or severity of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Pyzina Kid Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, lack of appetite, nausea, vomiting, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Pyzina Kid Tablet:
Co-administration of Teriflunomide with Pyzina Kid Tablet may increase the risk or severity of liver damage.

How to manage the interaction:
Although taking Teriflunomide and Pyzina Kid Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor immediately: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, or bleeding. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Pyzina Kid Tablet:
Taking rifampicin together with Pyzina Kid Tablet can cause liver problems.

How to manage the interaction:
Although there is an interaction between Pyzina Kid Tablet and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience fever, rash, less desire to eat, nausea, vomiting, fatigue, right upper abdominal pain, or dark urine, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Pyzina Kid Tablet:
Co-administration of leflunomide with Pyzina Kid Tablet may increase the risk or severity of liver problems.

How to manage the interaction:
Although taking Leflunomide and Pyzina Kid Tablet together can cause an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

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  • THEOPHYLLINE
  • PREDNISOLONE
  • PHENOBARBITAL
  • VALPROIC ACID
  • FLURAZEPAM
  • TRIAZOLAM
  • DIAZEPAM
  • WARFARIN
  • PHENINDIONE
  • PROCAINAMIDE
  • ALFENTANIL
  • MIDAZOLAM
  • HALOPERIDOL
  • CHLORPROMAZINE
  • PARACETAMOL
  • PHENYTOIN
  • KETOCONAZOLE

Habit Forming

No

Special Advise

 

  • Your doctor may advise you to get regular blood tests while taking PYZINA KID TABLET to monitor your liver function.
  • Consult a pulmonologist or lung specialist if you have had a bad cough for 3 weeks or longer, chest pain, coughing up blood or sputum from deep inside the lungs.
  • A monthly liver function test is advisable while using PYZINA KID TABLET.

 

Diet & Lifestyle Advise

 

  • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
  • Vitamin C-rich foods such as kiwi, broccoli, and bell pepper help in improving the immune system.
  • Avoid processed and fried foods.
  • Warm ginger tea or warm soup can help in providing relief from a cough.
  • Avoid foods and drinks containing histamine or tyramine such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
  • Quit smoking and avoid alcohol consumption.

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