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Written By Veda Maddala , M Pharmacy
Reviewed By Sureshvarma D , MPharma
48 Hrs returnable
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PROMISTIN 1MILLION IU INJECTION, Pack of 1 INJECTION
PROMISTIN 1MILLION IU INJECTION, Pack of 1 INJECTION
PROMISTIN 1MILLION IU INJECTION, Pack of 1 INJECTION
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COLISTIMETHATE-1M.I.U
PARENTERAL
Not Returnable
Apr-24
ANTIBIOTICS
INDIA
Fusion House, Plot No. 22, H.No 8-2-350/B, Road No. 3, Banjara Hills, Hyderabad, Telangana-500034
Other Info - PRO1182
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FAQs

PROMISTIN 1MILLION IU INJECTION contains Colistimethate, an antibiotic that works by binding to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stops the leakage of cell contents. Thereby, damages bacterial cell membranes and kills bacteria.
You are not recommended to take PROMISTIN 1MILLION IU INJECTION with gentamicin as co-administration of these two medicines may increase the risk of severe adverse effects such as kidney problems, hearing loss or respiratory depression especially in elderly people and in those who have preexisting kidney disease or who are dehydrated. However, please consult your doctor before taking PROMISTIN 1MILLION IU INJECTION with other medicines.
PROMISTIN 1MILLION IU INJECTION may cause dizziness as a common side effect. Avoid driving if you feel dizzy after taking PROMISTIN 1MILLION IU INJECTION. However, if the condition persists or worsens, please consult a doctor.
PROMISTIN 1MILLION IU INJECTION should be used with caution in patients receiving dialysis (the process of filtration and purification of blood using a machine). Therefore, if you are receiving dialysis, please inform your doctor before taking PROMISTIN 1MILLION IU INJECTION so that the dose may be adjusted accordingly.
You are recommended to take PROMISTIN 1MILLION IU INJECTION with extreme caution if you have kidney disease as it may worsen the condition. Regular monitoring of kidney functioning is recommended while taking PROMISTIN 1MILLION IU INJECTION. Therefore, inform your doctor if you have any kidney problems before taking PROMISTIN 1MILLION IU INJECTION.
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  1. https://www.medicines.org.uk/emc/files/pil.5648.pdf
  2. https://www.drugs.com/cdi/colistimethate.html

PROMISTIN 1MILLION IU INJECTION belongs to a class of drugs called antibiotics used in the treatment of severe bacterial infections. Bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. PROMISTIN 1MILLION IU INJECTION does not work against infections caused by a virus.

PROMISTIN 1MILLION IU INJECTION contains Colistimethate, an antibiotic that works by binding to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thereby, damaging bacterial cell membranes and kills bacteria.

Take PROMISTIN 1MILLION IU INJECTION as prescribed by your doctor. You are advised to take PROMISTIN 1MILLION IU INJECTION for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, stomach upset, tingling, or difficulty in breathing. Most of these side effects of PROMISTIN 1MILLION IU INJECTION do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to PROMISTIN 1MILLION IU INJECTION or any other medicines, please tell your doctor. If you have myasthenia gravis (muscle weakness), kidney problems, or porphyria (a disorder in the formation of red blood pigment), inform your doctor before taking PROMISTIN 1MILLION IU INJECTION. If you are pregnant or breastfeeding, please inform your doctor before taking PROMISTIN 1MILLION IU INJECTION. Special care should be taken in new-born and premature babies as kidneys are not developed fully. Drive only if you are alert as PROMISTIN 1MILLION IU INJECTION may cause confusion, vision problems, or dizziness.  If you are on dialysis, inform your doctor before taking PROMISTIN 1MILLION IU INJECTION so that the dose may be reduced accordingly.

Several bacterial infections

Medicinal Benefits Mweb

PROMISTIN 1MILLION IU INJECTION contains Colistimethate, a narrow-spectrum antibiotic that is active against gram-negative bacteria. PROMISTIN 1MILLION IU INJECTION binds to bacterial cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thereby, damages bacterial cell membranes and kills bacteria. PROMISTIN 1MILLION IU INJECTION is used when other antibiotics are not suitable.

PROMISTIN 1MILLION IU INJECTION will be administered by a healthcare professional; do not self-administer.
  • Dizziness
  • Stomach upset
  • Tingling
  • Difficulty in breathing

If you are allergic to PROMISTIN 1MILLION IU INJECTION or any other medicines, please tell your doctor. If you have myasthenia gravis (muscle weakness), kidney problems, or porphyria (a disorder in the formation of red blood pigment), inform your doctor before taking PROMISTIN 1MILLION IU INJECTION. If you are pregnant or breastfeeding, please inform your doctor before taking PROMISTIN 1MILLION IU INJECTION. Special care should be taken in new-born and premature babies as kidneys are not developed fully. Drive only if you are alert as PROMISTIN 1MILLION IU INJECTION may cause confusion, vision problems, or dizziness. If you are on dialysis, inform your doctor before taking PROMISTIN 1MILLION IU INJECTION so that the dose may be reduced accordingly. Inform your anesthetist that you are taking PROMISTIN 1MILLION IU INJECTION as it may increase the effects of muscle relaxants used in general anesthesia. You are recommended to complete the full course of PROMISTIN 1MILLION IU INJECTION as prescribed by your doctor for effective results.

verifiedApollotooltip
ColistinBCG vaccine
Critical
ColistinNeomycin
Severe
ColistinBCG vaccine
Critical
How does the drug interact with PROMISTIN 1MILLION IU INJECTION:
Coadministration of PROMISTIN 1MILLION IU INJECTION along with BCG vaccine can reduce the treatment outcomes.

How to manage the interaction:
Taking PROMISTIN 1MILLION IU INJECTION with BCG vaccine is avoided as it may lead to an interaction, please consult your doctor before taking it.
ColistinNeomycin
Severe
How does the drug interact with PROMISTIN 1MILLION IU INJECTION:
Combining PROMISTIN 1MILLION IU INJECTION with Neomycin can increase the risk or severity of kidney problems.

How to manage the interaction:
Although there is a possible interaction between PROMISTIN 1MILLION IU INJECTION and Neomycin, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, Rash, Dizziness, or Fever, consult a doctor. Do not stop using any medications without a doctor's advice.
ColistinRocuronium bromide
Severe
How does the drug interact with PROMISTIN 1MILLION IU INJECTION:
Coadministration of Rocuronium bromide with PROMISTIN 1MILLION IU INJECTION may increase the side effects of Rocuronium bromide.

How to manage the interaction:
Although there is a possible interaction between PROMISTIN 1MILLION IU INJECTION and Rocuronium bromide, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, Rash, Dizziness, or Fever, consult a doctor. Do not stop using any medications without a doctor's advice.
ColistinAmikacin
Severe
How does the drug interact with PROMISTIN 1MILLION IU INJECTION:
Coadministration of PROMISTIN 1MILLION IU INJECTION with Amikacin can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between PROMISTIN 1MILLION IU INJECTION and Amikacin, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ColistinKanamycin
Severe
How does the drug interact with PROMISTIN 1MILLION IU INJECTION:
Coadministration of PROMISTIN 1MILLION IU INJECTION with Kanamycin can increase the level and risk of PROMISTIN 1MILLION IU INJECTION side effects.

How to manage the interaction:
Although there is a possible interaction between PROMISTIN 1MILLION IU INJECTION and Kanamycin, you can take these medicines together if prescribed by your doctor. However, if you experience shortness of breath, swelling, muscle pain, dizziness, or palpitations call your doctor right away. Do not stop using any medications without a doctor's advice.
ColistinTobramycin
Severe
How does the drug interact with PROMISTIN 1MILLION IU INJECTION:
Coadministration of Tobramycin with PROMISTIN 1MILLION IU INJECTION can increase the blood levels and risk of PROMISTIN 1MILLION IU INJECTION side effects.

How to manage the interaction:
Although there is a possible interaction between PROMISTIN 1MILLION IU INJECTION and Tobramycin, you can take these medicines together if prescribed by your doctor. However, if you experience, shortness of breath, muscle pain, dizziness, or palpitations, contact your doctor immediately. Do not stop using any medications without a doctor's advice.
ColistinSuxamethonium
Severe
How does the drug interact with PROMISTIN 1MILLION IU INJECTION:
Using Suxamethonium together with PROMISTIN 1MILLION IU INJECTION may increase the effects of Suxamethonium.

How to manage the interaction:
Although there is a possible interaction between PROMISTIN 1MILLION IU INJECTION and Suxamethonium, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, Rash Paresthesia (tingling or pricking sensation) Dizziness Slurred speech Vertigo, or Fever, consult a doctor. Do not stop using any medications without a doctor's advice.
ColistinGentamicin
Severe
How does the drug interact with PROMISTIN 1MILLION IU INJECTION:
Co-administration of PROMISTIN 1MILLION IU INJECTION with Gentamicin can increase the levels and risk of PROMISTIN 1MILLION IU INJECTION side effects.

How to manage the interaction:
Although there is a possible interaction between PROMISTIN 1MILLION IU INJECTION and Gentamicin, you can take these medicines together if prescribed by your doctor. However, if you experience weight gain or loss suddenly, muscle pain, dizziness, or palpitations, call your doctor right away. Do not stop using any medications without a doctor's advice.
ColistinStreptomycin
Severe
How does the drug interact with PROMISTIN 1MILLION IU INJECTION:
Coadministration of Streptomycin with PROMISTIN 1MILLION IU INJECTION may increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between PROMISTIN 1MILLION IU INJECTION and Streptomycin, you can take these medicines together if prescribed by your doctor. However, if you experience shortness of breath, muscle pain, dizziness, or palpitations, call a doctor right away. Do not stop using any medications without a doctor's advice.
ColistinPancuronium
Severe
How does the drug interact with PROMISTIN 1MILLION IU INJECTION:
Using Pancuronium with PROMISTIN 1MILLION IU INJECTION can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between PROMISTIN 1MILLION IU INJECTION and Pancuronium, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, rash, dizziness, or fever, consult a doctor. Do not stop using any medications without a doctor's advice.
verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
  • AMIKACIN
  • NETILIMICIN
  • TOBRAMYCIN
  • GENTAMICIN
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • AZITHROMYCIN
  • CIPROFLOXACIN
  • NORFLOXACIN
  • OFLOXACIN
No
  • Regular blood tests are recommended to monitor the levels of PROMISTIN 1MILLION IU INJECTION in blood and kidney functioning.
  • Inform your anaesthetist that you are taking PROMISTIN 1MILLION IU INJECTION as it may increase the effects of muscle relaxants used in general anaesthesia.
  • Take probiotics after completing the full course of PROMISTIN 1MILLION IU INJECTION to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhea. Certain fermented foods like cheese, yogurt, kombucha, sauerkraut, and kimchi can restore the good bacteria of the intestine.
  • Include fiber-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fiber-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as whole-grain bread and brown rice should be included in your diet.
  • Make sure you drink plenty of water or other fluids every day while you are taking PROMISTIN 1MILLION IU INJECTION.
  • Avoid alcohol consumption as it may increase adverse effects.

PROMISTIN 1MILLION IU INJECTION Substitute

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