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  1. Home
  2. Medicine

  3. Posalup 300Mg/16.7Ml Injection 1's

Prescription drug
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Composition :

POSACONAZOLE-18MG

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

ANTIFUNGALS

Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3Rd Floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India Country Of Origin: India
Other Info - POS0122

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:47 AM IST

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FAQs

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Limit or avoid consumption of alcohol while on treatment with Posalup 300Mg/16.7Ml Injection as it may increase the risk of serious side effects.

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Pregnancy

Caution

Posalup 300Mg/16.7Ml Injection is not recommended for use in pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Posalup 300Mg/16.7Ml Injection.

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Breast Feeding

Caution

There is no substantial research yet on using Posalup 300Mg/16.7Ml Injection in breastfeeding women. Inform your doctor if you are a nursing mother before taking Posalup 300Mg/16.7Ml Injection; your doctor will decide whether Posalup 300Mg/16.7Ml Injection can be taken by breastfeeding mothers.

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Driving

Caution

It is unknown whether Posalup 300Mg/16.7Ml Injection alters the ability to drive, so do not drive or operate machinery if you experience any symptoms affecting your ability to concentrate and react.

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Liver

Caution

Inform your doctor before receiving the Posalup 300Mg/16.7Ml Injection if you have a liver impairment/disorder history. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Inform your doctor before receiving the Posalup 300Mg/16.7Ml Injection if you have a kidney impairment/disorder history. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Consult your doctor

Please consult your doctor. Your doctor will prescribe a suitable dose based on your child's age and condition.

Product Substitutes

Reference

  1. https://medlineplus.gov/druginfo/meds/a616017.html
  2. https://www.drugs.com/drug-interactions/posaconazole.html
  3. https://pubmed.ncbi.nlm.nih.gov/16961575/#:~:text=Posaconazole%2C%20a%20new%20triazole%20antifungal,fungi%20except%20Pneumocystis%20and%20Pythium.
  4. https://go.drugbank.com/drugs/DB01263
  5. https://mft.nhs.uk/app/uploads/sites/10/2021/11/Posaconazole-NAC-PIL.pdf

About Posalup 300Mg/16.7Ml Injection

Posalup 300Mg/16.7Ml Injection is in a class of medications called azole antifungals. It is used to prevent and treat fungal infections in adults and children two years of age and older with a weakened ability to fight infection. Besides this, it is also used to treat invasive aspergillosis (a serious fungal infection that begins in the lungs and spreads through the bloodstream to other organs) in adults and teenagers 13 years of age and older. Any disease caused by a fungus is known as a fungal infection.

Posalup 300Mg/16.7Ml Injection contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.

Posalup 300Mg/16.7Ml Injection will be administered by a qualified healthcare professional. You may sometimes experience injection site reactions, fever, headache, chills or shaking, stomach pain, constipation, diarrhoea, nosebleeds and coughing. Most of these side effects of Posalup 300Mg/16.7Ml Injection do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Inform your doctor if you are allergic or hypersensitive to any component present in Posalup 300Mg/16.7Ml Injection or if you are pregnant, suspect you are pregnant, plan to have a baby or are breastfeeding; your doctor will prescribe Posalup 300Mg/16.7Ml Injection only if the benefits outweigh the risk. Before taking the Posalup 300Mg/16.7Ml Injection, inform your doctor about your medical history and ongoing therapies to rule out any potential adverse effects or interactions.

Uses of Posalup 300Mg/16.7Ml Injection

Fungal infections

Medicinal Benefits Mweb

Medicinal Benefits

It is used to prevent and treat fungal infections in adults and children two years of age and older with a weakened ability to fight infection. It is also used to treat invasive aspergillosis (a serious fungal infection that begins in the lungs and spreads through the bloodstream to other organs) in adults and teenagers 13 years of age and older. Posalup 300Mg/16.7Ml Injection contains a medicine called posaconazole. It is a triazole antifungal agent and exerts its antifungal activity through the blockage of certain enzymes (P-450 dependent enzyme, sterol 14α-demethylase). This leads to inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, and the accumulation of methylated sterol precursors. This results in the inhibition of fungal cell growth and cell death. Thus, it treats infections.

Directions for Use

Posalup 300Mg/16.7Ml Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Side Effects of Posalup 300Mg/16.7Ml Injection

  • Injection site reactions
  • Fever
  • Headache
  • Chills or shaking
  • Constipation
  • Stomach pain
  • Diarrhoea
  • Nosebleeds
  • Coughing

Drug Warnings

Keep your doctor informed about your health condition and medicines to rule out any side effects. Posalup 300Mg/16.7Ml Injection is restricted to people sensitive to product constituents or other antifungal medicines. During pregnancy and lactation, posaconazole should only be used after careful risk/benefit considerations, so before taking Posalup 300Mg/16.7Ml Injection, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. It is unknown whether it is safe to consume alcohol with Posalup 300Mg/16.7Ml Injection. However, as a precautionary measure, it is advisable not to take or limit alcohol.

Drug-Drug Interactions

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PosaconazoleIsavuconazole
Critical
PosaconazoleZiprasidone
Critical

Drug-Drug Interactions

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PosaconazoleIsavuconazole
Critical
How does the drug interact with Posalup 300Mg/16.7Ml Injection:
When Isavuconazole is taken with Posalup 300Mg/16.7Ml Injection, it can increase the levels of isavuconazole in the blood.

How to manage the interaction:
Although there is an interaction between isavuconazole and Posalup 300Mg/16.7Ml Injection, it can be taken if prescribed by the doctor. However, if you experience nausea, vomiting, diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PosaconazoleZiprasidone
Critical
How does the drug interact with Posalup 300Mg/16.7Ml Injection:
Coadministration of Posalup 300Mg/16.7Ml Injection with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Posalup 300Mg/16.7Ml Injection with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
PosaconazoleEliglustat
Critical
How does the drug interact with Posalup 300Mg/16.7Ml Injection:
Taking eliglustat with Posalup 300Mg/16.7Ml Injection can increase the levels of eliglustat in the blood.

How to manage the interaction:
Although there is an interaction between Posalup 300Mg/16.7Ml Injection and eliglustat, they can be taken together if prescribed by a doctor. However, contact a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, a slow heart rate, or a weak pulse. Do not discontinue any medications without consulting a doctor.
PosaconazoleSimvastatin
Critical
How does the drug interact with Posalup 300Mg/16.7Ml Injection:
Taking Posalup 300Mg/16.7Ml Injection with Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver problems and rhabdomyolysis (which involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Posalup 300Mg/16.7Ml Injection and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark-colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
PosaconazoleEplerenone
Critical
How does the drug interact with Posalup 300Mg/16.7Ml Injection:
Coadministration of Posalup 300Mg/16.7Ml Injection with eplerenone can increase the blood levels of eplerenone. This can increase the risk of serious side effects, including hyperkalemia (high blood potassium).

How to manage the interaction:
Although there is an interaction between Posalup 300Mg/16.7Ml Injection and eplerenone, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
PosaconazoleCerivastatin
Critical
How does the drug interact with Posalup 300Mg/16.7Ml Injection:
Taking cerivastatin with Posalup 300Mg/16.7Ml Injection can increase the blood levels of cerivastatin.

How to manage the interaction:
Although there is an interaction between Posalup 300Mg/16.7Ml Injection and cerivastatin, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, dark-colored urine, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
PosaconazoleTolvaptan
Critical
How does the drug interact with Posalup 300Mg/16.7Ml Injection:
Taking Tolvaptan and Posalup 300Mg/16.7Ml Injection together results in an increase in the levels and effects of Tolvaptan.

How to manage the interaction:
Although there is an interaction between Tolvaptan and Posalup 300Mg/16.7Ml Injection, it can be taken if prescribed by a doctor. However, consult a doctor if you experience difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, or seizures (fits). Do not stop using any medications without a doctor's advice.
PosaconazolePimozide
Critical
How does the drug interact with Posalup 300Mg/16.7Ml Injection:
Taking pimozide with Posalup 300Mg/16.7Ml Injection can increase the levels of pimozide in the blood, which can lead to an increased risk of abnormal heart rhythm.

How to manage the interaction:
Although there is an interaction between Posalup 300Mg/16.7Ml Injection and pimozide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe or prolonged diarrhea, vomiting dizziness, lightheadedness, fainting, or shortness of breath. Do not discontinue any medications without consulting a doctor.
PosaconazoleTicagrelor
Critical
How does the drug interact with Posalup 300Mg/16.7Ml Injection:
Co-administration of Posalup 300Mg/16.7Ml Injection with Ticagrelor can increase the risk of bleeding.

How to manage the interaction:
Taking Ticagrelor with Posalup 300Mg/16.7Ml Injection is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue any medications without consulting a doctor.
PosaconazoleSilodosin
Critical
How does the drug interact with Posalup 300Mg/16.7Ml Injection:
Coadministration of silodosin and Posalup 300Mg/16.7Ml Injection may significantly increase the blood levels and effects of silodosin.

How to manage the interaction:
Although there is an interaction between Posalup 300Mg/16.7Ml Injection and Silodosin, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, nasal congestion, and headache. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • APIXABAN

Habit Forming

No

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals if you take Posalup 300Mg/16.7Ml Injection for more than one day.
  • Do not use other over-the-counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Posalup 300Mg/16.7Ml Injection.
  • Continue taking your normal regular diet unless your doctor prescribes a specific diet.
  • It is advisable to follow a candida diet during yeast infections. This diet excludes sugar, gluten, certain dairy products, and alcoholic beverages and switches to low-sugar fruits, non-starchy vegetables, and gluten-free foods.
  • A very high sugar or high-carbohydrate diet may increase the count of Candida in some people. It is better to avoid or limit alcohol and caffeine intake during the Posalup 300Mg/16.7Ml Injection treatment to enhance a healthy lifestyle practice.

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