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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Last Updated Aug 20, 2024 | 1:18 PM IST
48 Hrs returnable
COD available

Online payment accepted

Prescription drug

Whats That

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Composition :

PLERIXAFOR-24MG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

Apr-24
Prescription drug
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Therapeutic Class

CHEMOTHERAPY

Country of origin

India
Other Info - PLE0092

Author Details

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FAQs

Plerixa 24 mg Injection 1.2 ml contains Plerixafor, which works by binding to the chemokine receptor CXCR4 and inhibits the binding of its cognate ligand CXCL12.
Plerixa 24 mg Injection 1.2 ml may cause tumor cell mobilization and haematological effects such as increased lymphocytes, decreased platelet count, and splenic rupture in some patients. Hence, inform your oncologist about your complete medical history, including current medication, to rule out any side effects/interactions.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

It is unknown whether Plerixa 24 mg Injection 1.2 ml interacts with alcohol or not. Please consult your doctor.

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Pregnancy

Unsafe

Plerixa 24 mg Injection 1.2 ml is not recommended for use in pregnancy as it may harm your fetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Plerixa 24 mg Injection 1.2 ml. Effective birth control is necessary during treatment and for one week after your last dose.

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Breast Feeding

Unsafe

Plerixa 24 mg Injection 1.2 ml is not recommended if you are breastfeeding. You should not breastfeed while taking this medication and for one week after your last dose.

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Driving

Not applicable

Plerixa 24 mg Injection 1.2 ml is generally administered to hospitalized patients. Driving is not advised after taking this medicine.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Plerixa 24 mg Injection 1.2 ml. A dose adjustment may be made, or a suitable alternative may be advised based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Plerixa 24 mg Injection 1.2 ml. A dose adjustment may be made, or a suitable alternative may be advised based on your condition.

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Children

Unsafe

Plerixa 24 mg Injection 1.2 ml is not recommended for use in children as the safety and efficacy are not established.

About Plerixa 24 mg Injection 1.2 ml

Plerixa 24 mg Injection 1.2 ml belongs to the class of hemopoietic stem cell mobilizer. It is used in the treatment of Non-Hodgkin’s Disease (a blood cancer that affects your lymph system) and multiple myeloma (a type of cancer that affects the plasma cells of the bone marrow) in combination with granulocyte-colony stimulating factor (G-CSF).

Plerixa 24 mg Injection 1.2 ml contains Plerixafor, which belongs to the hemopoietic stem cell mobilizer class or drugs. It works by binding to the chemokine receptor CXCR4 and inhibits the binding of its cognate ligand CXCL12.

Plerixa 24 mg Injection 1.2 ml may cause certain side effects, such as nausea, vomiting, headache, dizziness, diarrhoea, flatulence, fatigue, and pain at the site of injection. These side effects do not require medical attention and gradually resolve over time. A trained healthcare professional will administer it. Do not self-administer.

Avoid taking it and inform your doctor if you are allergic to Plerixa 24 mg Injection 1.2 ml or its components. Before administration, inform your doctor if you have liver/kidney disease, cardiac disorders, blood disorders or respiratory conditions. This medicine is known to cause fetal harm in pregnant women. Hence, inform your doctor if you are pregnant or are planning to become pregnant. Breastfeeding should be discontinued during the treatment.

Uses of Plerixa 24 mg Injection 1.2 ml

Multiple Myeloma, Non-Hodgkin’s Disease.

Medicinal Benefits Mweb

Medicinal Benefits

Plerixa 24 mg Injection 1.2 ml contains Plerixafor, which belongs to the hemopoietic stem cell mobilizer class or drugs. It works by binding to the chemokine receptor CXCR4 and inhibiting its cognate ligand CXCL12 binding. This mobilizes hematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation in cancer patients.

Directions for Use

Plerixa 24 mg Injection 1.2 ml will be administered by a trained healthcare professional. Hence, do not self-administer. 

Drug Warnings

Plerixa 24 mg Injection 1.2 ml should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease, cardiac disorders, blood disorders, anaemia, or respiratory conditions. Plerixa 24 mg Injection 1.2 ml may cause the potential for tumor cell mobilization in leukemia patients, haematological effects, and splenic rupture in some patients. Hence, careful monitoring should be done during the entire treatment. This medicine is known to cause fetal harm in pregnant women. Hence, inform your doctor if you are pregnant or are planning to become pregnant. Breastfeeding should be discontinued in nursing mothers during the treatment. Plerixa 24 mg Injection 1.2 ml should be avoided in children as safety is not established.

Habit Forming

No

Special Advise

  • A blood test should be performed, such as LFT, RFT, and PFT, to check for liver function and pulmonary function.
  • Weekly blood tests should be done during the treatment to check for CBC (Complete blood count).
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