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  3. Plagerine 75 mg Tablet 10's

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Hari Kumar , MBBS

Composition :

CLOPIDOGREL-75MG

Manufacturer/Marketer :

Micro Labs Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

NPPA :

Regulated

Therapeutic Class

[ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS]

Country of origin

India

Manufacturer/Marketer address

No. 28 Sundar Industrial Estate,N.T.Y Layout Mysore Road , Bangalore - 560026, India
Other Info - PLA0011

Author Details

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FAQs

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Alcohol

Safe if prescribed

You can drink alcohol with Plagerine 75 Tablet . But do not drink too much while taking this medicine. It can irritate your stomach.

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Pregnancy

Consult your doctor

Plagerine 75 Tablet should not be taken until prescribed. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Breast Feeding

Consult your doctor

Plagerine 75 Tablet should not be taken until prescribed. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

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Driving

Safe if prescribed

Plagerine 75 Tablet has no or negligible influence on the ability to drive or use machines.

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Liver

Consult your doctor

No dosage adjustment is necessary in patients with liver disease.

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Kidney

Consult your doctor

Plagerine 75 Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Plagerine 75 Tablet is not recommended for children. The safety and effectiveness of Plagerine 75 Tablet have not been established in children due to limited testing of this drug on children by competent authorities across the world.

About Plagerine 75 Tablet

Plagerine 75 Tablet consists of the anti-platelet drug (blood thinner) primarily taken for the prevention of heart attack or stroke in people at high risk of heart disease. A heart attack generally refers to the blocked flow of blood to the heart because of the blockage of arteries. A heart blockage is most often a build-up of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries).

Plagerine 75 Tablet belongs to a class of medications called a blood thinner or an antiplatelet medication. Plagerine 75 Tablet plays a vital role in preventing the formation of harmful blood clots (plaque) in your veins. It makes your blood flow easy through your veins making it less likely to form a serious blood clot. So, an intake of Plagerine 75 Tablet helps prevent blood clots if you have an increased risk of having severe chest pain (unstable angina or heart attack), stroke, peripheral arterial disease (heart problem due to narrowed blood vessels).

The recommended daily dose of Plagerine 75 Tablet is 75 mg once daily orally, with or without food. It should be swallowed whole with a glass of water. Do not chew, bite or break it. Your doctor will advise you how often you take your tablets based on your medical condition. In some cases, you may experience nosebleeds, heavier periods, bleeding gums, easy bruising, diarrhoea, stomach pain, indigestion, or heartburn. If the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Stopping a sudden intake of Plagerine 75 Tablet may worsen your condition and increase your risk of cardiovascular death, heart attack, and stroke. Let your doctor know if you have any liver, kidney, or heart problems. Plagerine 75 Tablet should be taken cautiously in pregnant or breastfeeding women. It should be not given to people with a bleeding disorder (haemophilia), active pathological bleeding, like a peptic ulcer, or bleeding in the brain (intracranial haemorrhage). Do not take Plagerine 75 Tablet with aspirin or ibuprofen for pain relief while you are using Plagerine 75 Tablet . It may increase the chance of having stomach ulcers or severe gastric bleeding.

Uses of Plagerine 75 Tablet

Prevention of heart attack, Prevention of stroke, Prevention of heart related chest pain (angina)

Medicinal Benefits Mweb

Key Benefits

Plagerine 75 Tablet plays a vital role to prevent the formation of harmful blood clots in your blood vessels by making platelets (clotting agents) sticking together. Thus, it helps to reduce the risk of heart attack, stroke, unstable angina (heart related chest pain), peripheral arterial disease (blocked or poor blood flow due to narrowed blood vessels) in heart disease patients and patient who have undergone recent heart surgery with stent.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Side Effects of Plagerine 75 Tablet

  • Nosebleeds
  • Heavier periods
  • Bleeding gums
  • Easy bruising
  • Diarrhoea
  • Stomach pain
  • Indigestion or heartburn

Drug Warnings

Indigestion medicines known as proton pump inhibitors like omeprazole should be used with caution while taking Plagerine 75 Tablet . Prolonged use of Plagerine 75 Tablet can cause bleeding problems (like nosebleeds, heavier periods, bleeding gums, and easy bruising). If you are going to have any surgery, discontinue taking Plagerine 75 Tablet 5 days before the surgery. Discontinuation of Plagerine 75 Tablet might increase the risk of heart attack, stroke, and other risks of cardiovascular events. So, do not stop taking Plagerine 75 Tablet of a sudden on your own decision. If you have had any recent stroke or heart attack, stop the intake of Plagerine 75 Tablet with painkillers like aspirin or ibuprofen as it can increase your stomach or gastrointestinal bleeding. Purpura (blood leakage under the skin) has been observed with the use of Plagerine 75 Tablet including in fatal cases.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Plagerine 75 mg Tablet:
Taking Plagerine 75 mg Tablet together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Plagerine 75 mg Tablet with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Plagerine 75 mg Tablet:
When Selexipag and Plagerine 75 mg Tablet are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Plagerine 75 mg Tablet with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
ClopidogrelDesirudin
Severe
How does the drug interact with Plagerine 75 mg Tablet:
Using desirudin together with Plagerine 75 mg Tablet may increase the risk of bleeding.

How to manage the interaction:
Taking Plagerine 75 mg Tablet with Desirudin together can result in an interaction, but it can be taken if your doctor has advised it. However, consult a doctor if you experience difficulty with bleeding, bleeding, bruising, feeling dizzy or lightheaded, dark or sticky stools, headache, or vomiting. Do not stop using any medications without a doctor's advice.
How does the drug interact with Plagerine 75 mg Tablet:
Taking loperamide with Plagerine 75 mg Tablet may significantly increase the blood levels of loperamide. This can lead to serious and complications such as irregular heart rhythm.

How to manage the interaction:
Although talking Plagerine 75 mg Tablet with loperamide may result in an interaction, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, or shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Plagerine 75 mg Tablet:
Taking Plagerine 75 mg Tablet with acalabrutinib may increase the risk of bleeding.

How to manage the interaction:
There could be a possible interaction between Plagerine 75 mg Tablet and Acalabrutinib, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding, like feeling dizzy or lightheaded, red or black, sticky stools, or severe headaches. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Plagerine 75 mg Tablet:
Taking rosuvastatin with Plagerine 75 mg Tablet can increase the blood levels of rosuvastatin. This can increase the risk of side effects.

How to manage the interaction:
Although taking Plagerine 75 mg Tablet together with Rosuvastatin may result in an interaction, it can be taken if prescribed by your doctor. However, consult your doctor immediately if you experience chills, joint pain or swelling, skin rash, itching, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Plagerine 75 mg Tablet:
Taking enoxaparin with Plagerine 75 mg Tablet can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Plagerine 75 mg Tablet and Enoxaparin, but they can be taken together if prescribed by a doctor. However, If you experience any unusual bleeding or have other signs of bleeding like feeling dizzy or lightheaded, red or black, sticky stools, or headache, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Plagerine 75 mg Tablet:
Taking Plagerine 75 mg Tablet with ticlopidine can reduced effectiveness of Plagerine 75 mg Tablet.

How to manage the interaction:
Taking Plagerine 75 mg Tablet and Ticlopidine together possibly has an interaction, but you can take these medications together if your doctor has advised it. Do not stop using any medications without talking to your doctor.
How does the drug interact with Plagerine 75 mg Tablet:
Taking Plagerine 75 mg Tablet with Dabigatran may increase the risk of bleeding.

How to manage the interaction:
Although there may be an interaction between Plagerine 75 mg Tablet and Apixaban, they can be taken together if advised by your doctor. However, consult your doctor immediately if you experience any unusual bleeding, dizziness or lightheadedness, red or black, sticky stools, or headaches. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Plagerine 75 mg Tablet:
Co-administration of Plagerine 75 mg Tablet with fluconazole can reduce the effectiveness of Plagerine 75 mg Tablet.

How to manage the interaction:
Plagerine 75 mg Tablet and Fluconazole may interact, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • WARFARIN
  • ASPIRIN
  • RIVAROXABAN
  • APIXABAN
  • IBUPROFEN
  • CITALOPRAM
  • OMEPRAZOLE

Habit Forming

No

Special Advise

  • As Plagerine 75 Tablet tends to increase bleeding, try to avoid injuries, keep away from sharp objects, and inform your doctor if you have peptic ulcers or injuries.

Diet & Lifestyle Advise

  • A low cholesterol diet and a regular exercise regime complement treatment with Plagerine 75 Tablet effectively.
  • Stick to a freshly prepared home-cooked meal and avoid processed, packed foods that contain hidden sugar and extra calories.
  • Try to replace most of your saturated fats with unsaturated fats can reduce total cholesterol and LDL cholesterol (bad cholesterol) in a short period.
  • Foods like avocados, olive oil, fatty fish and nuts contain many heart-healthy unsaturated fats, so eating them regularly is beneficial.
  • Include a diet enriched in fats like fish oils, polyunsaturated oils, and omega-3 fatty acids, which are good for heart health.
  • Quit smoking and avoid excessive intake of alcohol.

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