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  1. Home
  2. Medicine

  3. Pivikto 150 mg Tablet 28's

Prescription drug
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Composition :

ALPELISIB-150MG

Manufacturer/Marketer :

Sandoz Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

Therapeutic Class

KINASE INHIBITORS

Country of origin

SWITZERLAND

Manufacturer/Marketer address

Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Other Info - PIV0018

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:50 AM IST

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FAQs

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Avoid alcohol consumption while on treatment with Pivikto 150 mg Tablet .

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Pregnancy

Unsafe

Pivikto 150 mg Tablet should not be used during pregnancy. So, inform your doctor if you are pregnant or suspect pregnancy. You or your partner must use a reliable form of contraception to prevent pregnancy while taking these medications.

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Breast Feeding

Caution

Lactating women should not breastfeed throughout Pivikto 150 mg Tablet treatment and for one week following the final dosage.

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Driving

Caution

Pivikto 150 mg Tablet does not influence the ability to drive or use machines. However, go only if you are alert, as the Pivikto 150 mg Tablet may cause weakness or tiredness in some people.

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Liver

Caution

Limited information is available. Inform your doctor before taking the Pivikto 150 mg Tablet if you have had a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Kidney

Caution

No dose adjustment is recommended for patients with mild to moderate renal impairment (CLcr 30 to < 90 mL/min). The effect of severe renal impairment (CLcr < 30 mL/min) on alpelisib is unknown. So, inform your doctor before taking the Pivikto 150 mg Tablet if you have had a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.

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Children

Unsafe

Safety and effectiveness in patients below the age of 18 years have not been established. Hence, use is not recommended.

Reference

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/212526s000lbl.pdf
  2. https://www.breastcancer.org/types/metastatic
  3. https://give.breastcancer.org/give/294499/#!/donation/checkout?c_src=clipboard&c_src2=text-link
  4. https://www.breastcancer.org/treatment/targeted-therapy/piqray
  5. https://www.us.piqray.com/
  6. https://medlineplus.gov/druginfo/meds/a619036.html
  7. https://www.hcp.novartis.com/products/piqray/metastatic-breast-cancer/

About Pivikto 150 mg Tablet

Pivikto 150 mg Tablet belongs to a class of kinase inhibitors. It is used in conjunction with fulvestrant to treat postmenopausal women and men with hormone receptor (HR)-positive, HER2-negative, PIK3CA-mutated, advanced, or metastatic breast cancer.

Pivikto 150 mg Tablet contains Alpelisib. In breast cancers with a PIK3CA gene mutation, a protein called PI3K is involved in helping the cancer cells multiply and grow. By blocking the action of PI3K, Alpelisib helps stop the growth and spread of the cancer.

To treat your condition effectually, continue using Pivikto 150 mg Tablet for as long as your doctor has prescribed it. The most common side effects include rash, decreased appetite, weight loss, nausea, mouth sores, hair loss, tiredness and weakness, vomiting, changes in certain blood tests, allergic reactions, skin reactions, high blood sugar levels, lung problems, and diarrhea. You should talk to your doctor if you persistently experience these side effects.

Avoid taking Pivikto 150 mg Tablet if you are allergic to it. It is not recommended for use in pregnancy. Lactating women do not breastfeed during treatment with Pivikto 150 mg Tablet and for one week after the last dose. Alcohol should be avoided during treatment with this medicine. Safety and effectiveness in children have not been established.

Uses of Pivikto 150 mg Tablet

Advanced or metastatic breast cancer

Medicinal Benefits Mweb

Medicinal Benefits

Pivikto 150 mg Tablet contains Alpelisib, which belongs to a class of kinase inhibitors. It is used in conjunction with fulvestrant to treat postmenopausal women and men with hormone receptor (HR)-positive, HER2-negative, PIK3CA-mutated, advanced, or metastatic breast cancer. In breast cancers with a PIK3CA gene mutation, a protein called PI3K is involved in helping the cancer cells multiply and grow. By blocking the action of PI3K, Alpelisib helps stop the growth and spread of the cancer.

Directions for Use

Pivikto 150 mg Tablet should be swallowed as a whole with a glass of water. Do not crush, chew, or break the tablets. The doctor determines the dose and duration based on your health condition.

Side Effects of Pivikto 150 mg Tablet

  • Rash
  • Decreased appetite
  • Weight loss
  • Nausea
  • Mouth sores
  • Hair loss
  • Tiredness and weakness
  • Vomiting
  • Changes in certain blood tests
  • Severe allergic reactions
  • High blood sugar levels
  • Lung problems
  • Diarrhea

Drug Warnings

It is not advised during pregnancy, nursing, or for children or young adults under 18. Before taking the Pivikto 150 mg Tablet , inform your doctor about all your medical conditions (especially lung infections, diarrhoea, diabetics, kidney or liver impairment), sensitivities or allergic conditions, and all medications you use. Consult your doctor right away if you become pregnant while taking Pivikto 150 mg Tablet . Exposure of an unborn child to this medication could cause congenital disabilities, so you should not become pregnant or father a child while on this medication. Effective birth control is required throughout treatment and at least one week after treatment. You should not breastfeed while taking this medication for two weeks after your last dose.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • APALUTAMIDE
  • CARBAMAZEPINE
  • EDOXABAN
  • PRIMIDONE

Habit Forming

No

Special Advise

  • Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests to check your body's response to Pivikto 150 mg Tablet .
  • Pregnancy testing is recommended prior to starting treatment with Pivikto 150 mg Tablet .
  • Do not donate Sperm throughout treatment and at least one week after treatment.

Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

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