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Pirfenex 400 mg Tablet 15's

Pirfenex 400 mg Tablet 15's

About Pirfenex 400 mg Tablet 15's

Pirfenex 400 mg Tablet 15's is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults. IPF is an irreversible disease that is marked by a progressive decline in lung function. The tissues in the lungs become swollen and scarred over time, due to which it gets difficult to breathe deeply. The scarring makes it hard for the lungs to work properly.
 
Pirfenex 400 mg Tablet 15's contains ‘Pirfenidone’, which helps in reducing the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better. Pirfenex 400 mg Tablet 15's helps in slowing down the progress of idiopathic pulmonary fibrosis. 

In some cases, you may experience certain common side effects such as nausea, tiredness, diarrhoea, indigestion, loss of appetite, headache, and photosensitivity. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor before taking Pirfenex 400 mg Tablet 15's if you are pregnant or breastfeeding. Pirfenex 400 mg Tablet 15's may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Pirfenex 400 mg Tablet 15's as it could lead to increased dizziness. Pirfenex 400 mg Tablet 15's is not recommended for children below 18 years as safety and effectiveness have not been established. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Pirfenex 400 mg Tablet 15's

Idiopathic pulmonary fibrosis

Medicinal Benefits

Pirfenex 400 mg Tablet 15's is an anti-fibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF) in adults. Pirfenex 400 mg Tablet 15's can help effectively slow the rate of lung function decline by 50%. Pirfenex 400 mg Tablet 15's helps reduce the scarring and swelling in the lungs by decreasing the release/activity of naturally occurring growth factors in the body, thereby helps you breathe better. Pirfenex 400 mg Tablet 15's helps in slowing down the progress of idiopathic pulmonary fibrosis.

Directions for Use

Take Pirfenex 400 mg Tablet 15's with food. Swallow Pirfenex 400 mg Tablet 15's as a whole with a glass of water; do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pirfenex 400 mg Tablet 15's

  • Nausea
  • Tiredness
  • Diarrhoea
  • Indigestion/Stomach upset
  • Loss of appetite
  • Headache
  • Photosensitivity

Drug Warnings

Do not take Pirfenex 400 mg Tablet 15's if you are allergic to any of its components; if you have a severe or end-stage liver impairment or kidney disease requiring dialysis; if you are taking fluvoxamine (anti-depressant). Inform your doctor if you are taking any medicines that might make you photosensitive, if you smoke or have kidney or liver problems. Consult your doctor before taking Pirfenex 400 mg Tablet 15's if you are pregnant or breastfeeding. Pirfenex 400 mg Tablet 15's may cause tiredness and dizziness, so drive with caution. Avoid consuming alcohol with Pirfenex 400 mg Tablet 15's as it could lead to increased dizziness. Pirfenex 400 mg Tablet 15's is not recommended for children below 18 years as safety and effectiveness have not been established.

Drug Interactions

Drug-Drug Interactions: Pirfenex 400 mg Tablet 15's may interact with an anti-depressant (fluvoxamine), antibiotics (ciprofloxacin, enoxacin, rifampicin), antiarrhythmic (amiodarone, propafenone), antacid (omeprazole).

Drug-Food Interactions: Avoid grapefruit juice and chargrilled meats.

Drug-Disease Interactions: Inform your doctor if you have severe hepatic problems or end-stage renal impairment requiring dialysis.

Drug-Drug Interactions Checker List

  • FLUVOXAMINE
  • CIPROFLOXACIN
  • ENOXACIN
  • RIFAMPICIN
  • AMIODARONE
  • PROPAFENONE
  • OMEPRAZOLE

Habit Forming

No

Diet & Lifestyle Advise

  • Watch out for triggers that make the cough worse, such as smoke, foods, air-conditioning, high altitude, etc.
  • Exercise moderately. Eat healthily.
  • Follow the pulmonary rehabilitation program. It includes exercise, disease education, and group therapy.
  • Quit smoking.
  • Get ample rest.
  • Include green leafy vegetables, sweet potatoes, broccoli, tomatoes, carrots, mangoes, citrus fruits, berries, and cocoa.
  • Lean proteins such as fish, meat, and poultry are the best.
  • Hydration is important. Drink plenty of water, herbal tea, and fruit juices.
  • Avoid processed and refined foods.

Special Advise

  • Your doctor may advise liver function tests prior to the start of the treatment.
  • Regular blood tests are advised at the start of treatment with Pirfenex 400 mg Tablet 15's and monthly for every 6 months, and then for every 3 months thereafter to check the liver functioning.

Disease/Condition Glossary

Idiopathic pulmonary fibrosis (IPF): Idiopathic pulmonary fibrosis belongs to a group of interstitial lung diseases. It is an irreversible chronic disease marked by a progressive decline in lung function. The tissues in the lungs become inflamed and scarred over time, due to which it gets difficult to breathe properly. The scar tissue, known as fibrosis, becomes thick /stiff over time, making it hard for the lungs to work efficiently. This causes decreased lung function, which leads to increased breathlessness and coughing. Breathing difficulties can lead to other medical problems. Symptoms of IPF are shortness of breath, persistent dry cough, loss of appetite, weight loss, rounded and widened tips of the fingers and toes.

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