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  1. Home
  2. Medicine

  3. Pecloz MR 100mg/325mg/500mg Tablet

Prescription drug
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Written By ,
Reviewed By Sunny S , MBBS

Composition :

ACECLOFENAC-100MG + CHLORZOXAZONE-500MG + PARACETAMOL-325MG

Consume Type :

ORAL

Return Policy :

Not Returnable

Therapeutic Class

ANALGESICS

Country of origin

India
Other Info - PE15092

FAQs

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Pecloz MR 100mg/325mg/500mg Tablet with alcohol can cause liver problems, so should not be taken until prescribed if you are taking alcohol.

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Pregnancy

Safe if prescribed

Only consume Pecloz MR 100mg/325mg/500mg Tablet, if you are prescribed by a doctor.

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Breast Feeding

Safe if prescribed

Only consume Pecloz MR 100mg/325mg/500mg Tablet, if you are prescribed by a doctor

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Driving

Unsafe

Pecloz MR 100mg/325mg/500mg Tablet can impair the ability to drive. So, do not drive or operate heavy machinery that required mental alertness after taking Pecloz MR 100mg/325mg/500mg Tablet.

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Liver

Caution

Pecloz MR 100mg/325mg/500mg Tablet to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.

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Kidney

Caution

Pecloz MR 100mg/325mg/500mg Tablet to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Pecloz MR 100mg/325mg/500mg Tablet is not recommended for children below the age of 10 years. The safety and effectivenss of Pecloz MR 100mg/325mg/500mg Tablet has not been established in children due to limited testing of this drug on children by competent authorities across the world.

Product Substitutes

Reference

  1. https://www.drugs.com/pro/chlorzoxazone.html
  2. https://www.medicines.org.uk/emc/files/pil.4240.pdf
  3. https://www.medicines.org.uk/emc/files/pil.5164.pdf

About Pecloz MR 100mg/325mg/500mg Tablet

Pecloz MR 100mg/325mg/500mg Tablet is a combination drug that belongs to NSAIDs (non-steroidal anti-inflammatory drugs) or pain killers primarily used for pain relief and muscle relaxation. Muscle pain (myalgia) is widespread and generally refers to uncomfortable sensations in the muscles which can be due to illness, injury or excessive exercise. It can be continuous or can also occur at intervals.

Pecloz MR 100mg/325mg/500mg Tablet contains three medicines, namely: Aceclofenac (pain killer), Paracetamol (fever reducer/mild pain reliever) and Chlorzoxazone (muscle relaxant). Aceclofenac and Paracetamol together work by blocking the effect of a natural chemical messenger called cyclo-oxygenase (COX) enzymes that make another chemical (prostaglandins). These prostaglandins are produced at sites of damage or injury and cause inflammation and pain. On the other hand, Chlorzoxazone is a muscle relaxant that works by centrally acting on the spinal cord by depressing reflexes, thereby relieving pain and stiffness caused due to muscle strains and sprains.

Pecloz MR 100mg/325mg/500mg Tablet can be taken with or without food as advised by your doctor for the best results. Do not stop taking Pecloz MR 100mg/325mg/500mg Tablet even if you feel better to avoid any unpleasant side effects. Common side effects of Pecloz MR 100mg/325mg/500mg Tablet include nausea, vomiting, heartburn, stomach pain, diarrhoea, and loss of appetite. If any of these side effects get worse or do not subside, please visit your doctor immediately.

Pecloz MR 100mg/325mg/500mg Tablet should not be taken if you have any serious medical condition, severe kidney or liver disease, are planning to become pregnant or are pregnant. Also, consumption of alcohol should be avoided while taking Pecloz MR 100mg/325mg/500mg Tablet as it may increase the drowsiness and dizziness. So, driving a motor vehicle and operating heavy machinery should be avoided. Excess of paracetamol intake can cause liver damage so; its dose should not exceed more than 4 gm per day.

Uses of Pecloz MR 100mg/325mg/500mg Tablet

Musculoskeletal pain

Medicinal Benefits Mweb

Medicinal Benefits

Aceclofenac and Paracetamol together work by blocking the effect of a natural chemical messenger called cyclo-oxygenase (COX) enzymes that make another chemical (prostaglandins). These prostaglandins are produced at sites of damage or injury and cause inflammation and pain. On the other hand, Chlorzoxazone is a muscle relaxant that works by centrally acting on the spinal cord by depressing reflexes, thereby relieving pain and stiffness caused due to muscle strains and sprains.

Directions for Use

Take Pecloz MR 100mg/325mg/500mg Tablet as advised by your doctor. Preferably take it with a meal to avoid the upset of stomach. Swallow it as a whole, do not chew or crush it. Keep this medicine out of sight and reach of children.

Side Effects of Pecloz MR 100mg/325mg/500mg Tablet

  • Nausea
  • Vomiting
  • Heartburn
  • Stomach pain
  • Diarrhoea
  • Loss of appetite
  • Tiredness
  • Sleepiness

Drug Warnings

Pecloz MR 100mg/325mg/500mg Tablet should not be taken if you have any serious medical condition, severe kidney or liver disease, are planning to become pregnant or are pregnant. Also, consumption of alcohol should be avoided while taking Pecloz MR 100mg/325mg/500mg Tablet as it may increase the drowsiness and dizziness. So, driving a motor vehicle and operating heavy machinery should be avoided. Excess of paracetamol intake can cause liver damage so; its dose should not exceed more than 4 gm per day.

Drug-Drug Interactions

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AceclofenacAtenolol
Severe
ParacetamolOxazepam
Severe

Drug-Drug Interactions

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AceclofenacAtenolol
Severe
How does the drug interact with Pecloz MR 100mg/325mg/500mg Tablet:
Co-administration of Atenolol with Pecloz MR 100mg/325mg/500mg Tablet could increase the risk of low blood pressure.

How to manage the interaction:
Although there is a possible interaction between Atenolol and Pecloz MR 100mg/325mg/500mg Tablet, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience excessive sweating, shortness of breath, palpitations, or chest discomfort. Do not discontinue any medications without consulting a doctor.
ParacetamolOxazepam
Severe
How does the drug interact with Pecloz MR 100mg/325mg/500mg Tablet:
Co-administration of Pecloz MR 100mg/325mg/500mg Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Pecloz MR 100mg/325mg/500mg Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolKetamine
Severe
How does the drug interact with Pecloz MR 100mg/325mg/500mg Tablet:
Co-administration of ketamine and Pecloz MR 100mg/325mg/500mg Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Pecloz MR 100mg/325mg/500mg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolTeriflunomide
Severe
How does the drug interact with Pecloz MR 100mg/325mg/500mg Tablet:
Co-administration of Teriflunomide with Pecloz MR 100mg/325mg/500mg Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Pecloz MR 100mg/325mg/500mg Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolKetoconazole
Severe
How does the drug interact with Pecloz MR 100mg/325mg/500mg Tablet:
Co-administration of Pecloz MR 100mg/325mg/500mg Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Pecloz MR 100mg/325mg/500mg Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolLeflunomide
Severe
How does the drug interact with Pecloz MR 100mg/325mg/500mg Tablet:
Co-administration of Pecloz MR 100mg/325mg/500mg Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Pecloz MR 100mg/325mg/500mg Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with Pecloz MR 100mg/325mg/500mg Tablet:
Co-administration of Pecloz MR 100mg/325mg/500mg Tablet and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Pecloz MR 100mg/325mg/500mg Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolLomitapide
Severe
How does the drug interact with Pecloz MR 100mg/325mg/500mg Tablet:
Co-administration of Lomitapide and Pecloz MR 100mg/325mg/500mg Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Pecloz MR 100mg/325mg/500mg Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolMipomersen
Severe
How does the drug interact with Pecloz MR 100mg/325mg/500mg Tablet:
Co-administration of Mipomersen with Pecloz MR 100mg/325mg/500mg Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Pecloz MR 100mg/325mg/500mg Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ChlorzoxazoneMorphine
Severe
How does the drug interact with Pecloz MR 100mg/325mg/500mg Tablet:
Using Morphine together with Pecloz MR 100mg/325mg/500mg Tablet can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Co-administration of Morphine with Pecloz MR 100mg/325mg/500mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ALPRAZOLAM
  • ESCITALOPRAM
  • ZOLPIDEM
  • TRAMADOL
  • OXYCODONE
  • GABAPENTIN
  • TOPIRAMATE
  • PREGABALIN
  • FLUOXETINE
  • DULOXETINE
  • DIPHENHYDRAMINE
  • CETIRIZINE
  • BACLOFEN

Habit Forming

No

Diet & Lifestyle Advise

  • Try to increase the consumption of calcium and vitamin D, as recommended as part of a healthy bone diet.
  • Omega 3 fatty acid oils enriched food should include in your daily meal for keeping joints healthy.
  • Connective tissues are the “cellular glue” that connects and support vital organs in the body. This connective tissue is comprised of proteins like collagen and elastin. So the requirement of proteins are required for keeping your muscle healthy, so intake of high protein diets like fish (salmon, sardines, and tuna), chicken, and eggs for non-vegetarian. While legumes, nuts, seed and dairy items (milk, yoghurt, cheese) for a vegetarian person is recommended. 
  • Magnesium, Vitamin K and Zinc enriched foods can help in keeping your bones and muscle healthy so its intake should be enhanced in your daily diet plan. 
  • Physical activities like Tai chi, Yoga, swimming and walking have shown improvement in managing muscle pain. 
  • Do not sit for a longer duration. Try to take a gap of 10 minutes by brisk walking or stretching.

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