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Pacitane Tablet 30's

Pacitane Tablet 30's

About Pacitane Tablet 30's

Pacitane Tablet 30's belongs to a group of medicines called anti-spasmodic agents used as an adjunct to treat Parkinson’s disease and extrapyramidal symptoms (drug-induced movement disorders). Parkinson’s disease is a progressive neurological disorder in which the first signs are problems with movements. 

Pacitane Tablet 30's contains ‘Trihexyphenidyl’ which works by relaxing the muscles and nerve impulses that control muscle functioning. Besides this, Pacitane Tablet 30's also balances chemical messengers called neurotransmitters in the brain; thereby improving muscle control and reducing stiffness, thereby helps the muscles move naturally. 

In some cases, you may experience common side-effects such as nausea, vomiting, dizziness, constipation, weakness, headache, dry mouth, decreased urination, drowsiness, and feeling nervous or restless. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side-effects persist or worsen.

Consult your doctor if you are pregnant or breastfeeding. Pacitane Tablet 30's may cause drowsiness and dizziness, do not drive unless you are alert. Pacitane Tablet 30's should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Pacitane Tablet 30's as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your medicines and health condition to rule out any side-effects.

Uses of Pacitane Tablet 30's

Parkinson’s disease

Medicinal Benefits

Pacitane Tablet 30's belongs to a group of medicines called anti-spasmodic agents. Pacitane Tablet 30's is used to treat the symptoms of Parkinson’s disease and extrapyramidal symptoms (drug-induced movement disorders). Pacitane Tablet 30's exerts a direct inhibitory effect upon the parasympathetic nervous system. It works by relaxing the muscles and nerve impulses that control muscle functioning. Pacitane Tablet 30's improves muscle control and reduces stiffness, thereby helps the muscles move naturally. Pacitane Tablet 30's is used as an adjuvant therapy along with levodopa to treat Parkinson's disease. Additionally, Pacitane Tablet 30's is used to control drug-induced movement disorders caused by CNS drugs such as dibenzoxazepines, thioxanthenes, phenothiazines, and butyrophenones.

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, or crush the tablet/capsule.Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack; shake the pack well before each use.Dispersible tablet: Disperse the tablet in water and consume it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pacitane Tablet 30's

  • Nausea
  • Vomiting
  • Dizziness
  • Constipation
  • Weakness 
  • Headache
  • Dry mouth
  • Decreased urination
  • Drowsiness
  • Feeling nervous or restless

Drug Warnings

Do not take Pacitane Tablet 30's if you are allergic to any of its contents or if you have narrow-angle glaucoma. Do not discontinue Pacitane Tablet 30's on your own. Inform your doctor if you have glaucoma, prostate problems, urination problems, stomach ulcers, acidity, myasthenia gravis (muscle problems), tardive dyskinesia (involuntary facial movements), alcoholism, high blood pressure, heart, liver or kidney problems. Talk to your doctor immediately if you experience hallucinations. Consult your doctor if you are pregnant or breastfeeding. Pacitane Tablet 30's may cause drowsiness and dizziness, do not drive unless you are alert. Pacitane Tablet 30's should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Pacitane Tablet 30's as it could lead to increased drowsiness and dizziness.

Drug Interactions

Drug-Drug Interactions: Pacitane Tablet 30's may have interaction with antipsychotic (aripiprazole, lurasidone, olanzapine, risperidone, quetiapine, trifluoperazine), MAO inhibitor (rasagiline), antihistamine (diphenhydramine), anti-cholinergic (benztropine), anti-convulsant (clonazepam, lamotrigine, pregabalin), anti-depressants (escitalopram, duloxetine) anti-anxiety (alprazolam), and mild pain killers/fever-reducing agent (acetaminophen).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have arrhythmia (irregular heartbeats), autonomic neuropathy (nerve damage), gastrointestinal obstruction, glaucoma, urinary obstruction, infectious diarrhoea, tardive dyskinesia (involuntary facial movements), psychoses, high blood pressure, or fever.

Drug-Drug Interactions Checker List

  • ARIPIPRAZOLE
  • LURASIDONE
  • OLANZAPINE
  • RISPERIDONE
  • QUETIAPINE
  • TRIFLUOPERAZINE
  • RASAGILINE
  • DIPHENHYDRAMINE
  • BENZTROPINE MESYLATE
  • CLONAZEPAM
  • LAMOTRIGINE
  • PREGABALIN
  • ESCITALOPRAM
  • DULOXETINE
  • ALPRAZOLAM
  • ACETAMINOPHEN

Habit Forming

No

Diet & Lifestyle Advise

  • Maintain a healthy diet and exercise regularly.
  • Include a diet rich in iron, folate and magnesium. 
  • Regularly attend therapy sessions.
  • Perform meditation and yoga.
  • Follow a regular sleep pattern.
  • Avoid smoking and alcohol consumption.
  • Learn about your condition, understand the risk factors and follow the doctor’s treatment plan.

Special Advise

  • Take Pacitane Tablet 30's at least 2 hours after taking ketoconazole and antidiarrheal medicines as it may prevent the full absorption of trihexyphenidyl. Besides this, Pacitane Tablet 30's may prevent the complete absorption of antifungal agents like ketoconazole when these medicines are taken together.
  • Pacitane Tablet 30's can cause decreased sweating, resulting in a rise in body temperature (hyperthermia). This profound side effect is more significant in hot weather, so it is advisable to drink plenty of water, especially in summer. However, kidney patients should consult a doctor before consuming any fluid.
  • Take special care with your dental hygiene while using Pacitane Tablet 30's (like brushing, and flossing) and have regular dental check-ups.

Disease/Condition Glossary

Parkinson’s disease: It is a progressive neurological disorder in which the first signs are problems with movements. Dopamine is a naturally-occurring neurotransmitter in the brain which is reduced or absent in people with Parkinson’s disease. Due to this, problems arise with smooth and coordinated movements. Symptoms include decreased ability to smell, stooped posture, changes in voice, constipation, small/ cramped handwriting, tremor, slow movements, stiffness of arms, legs, trunk, and balance problems. 

Recommended for a 30-day course: 2 Strips

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