Open UP 150 Tablet

Open UP 150 Tablet belongs to a group of medicines called the biliary agents or gall stone dissolution agents used to treat gall stones, primary biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in bile and children above 6years with biliary and liver diseases caused by cystic fibrosis. 

Open UP 150 Tablet contains ursodeoxycholic acid, which is a naturally-occurring bile acid. Open UP 150 Tablet helps decrease the production of cholesterol in the blood, thereby dissolving gall bladder stones composed mainly of cholesterol. Open UP 150 Tablet has a protective effect on the liver cells from injury caused due to toxic bile acids and improves liver function.

Take Open UP 150 Tablet with food. You are advised to take Open UP 150 Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as abdominal discomfort, abdominal pain, diarrhoea, nausea, rash, dizziness, indigestion and weakness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Inform your doctor before taking Open UP 150 Tablet if you have variceal bleeding (high blood pressure in portal veins), ascites (excess abdominal fluid), liver encephalopathy or liver disease. Do not take Open UP 150 Tablet if you are pregnant or breastfeeding unless prescribed. Open UP 150 Tablet can be given to children above 6 years if prescribed by the doctor. Avoid consuming alcohol along with Open UP 150 Tablet as it could lead to increased drowsiness and liver damage. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Open UP 150 Tablet contains ursodeoxycholic acid, which is a naturally-occurring bile acid. It belongs to a group of medicines called the biliary agent or gall stone dissolution agents used to treat gall stones, primary biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in bile children above 6 years with biliary and liver diseases caused by cystic fibrosis. Open UP 150 Tablet breaks down the cholesterol that has formed into gall bladder stones, thereby dissolves the stones. Open UP 150 Tablet has a protective effect on the liver cells and the immune system, thereby improving liver function. Open UP 150 Tablet decreases the amount of cholesterol produced by the liver and absorbed by the intestine. In patients with primary biliary cirrhosis, Open UP 150 Tablet increases the bile flow.

Do not take Open UP 150 Tablet if you are allergic to any of its contents, if you have inflammation of gall bladder and bile ducts, narrowing or blockage bile ducts, biliary colic, calcified gallstones, improper constriction of the gallbladder, gastric or duodenal ulcer. Inform your doctor before taking Open UP 150 Tablet if you have variceal bleeding (high blood pressure in portal veins), ascites (excess abdominal fluid), liver encephalopathy or liver disease. Consult your doctor before taking Open UP 150 Tablet with other medicines as Open UP 150 Tablet might reduce the absorption of antibiotics (ciprofloxacin and dapsone) and antihypertensive agents (nitrendipine), increase the effect of immunosuppressants (cyclosporine), oral contraceptives (oestrogen) and cholesterol-lowering agents (clofibrate) might promote the formation of gallstones. Do not take Open UP 150 Tablet if you are pregnant or breastfeeding unless prescribed. Open UP 150 Tablet can be given to children above 6 years if prescribed by the doctor. Avoid consuming alcohol along with Open UP 150 Tablet as it could lead to increased drowsiness and liver damage. Keep your doctor informed about your health condition and medicines to rule out any unpleasant side-effects.

• Your doctor may advice regular liver function test to monitor the function of the liver and the progress of the treatment.
• Open UP 150 Tablet may rarely cause thinning and loss of hair, if there is excessive loss of hair consult your doctor for further advice.