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Alcohol
Unsafe
Onglyza 2.5 mg Tablet 14's is not advised to be taken with alcohol as it causes bizarre interactions. Both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) may occur, depending on how much and how often you drink.
Pregnancy
Caution
No harmful interaction has been reported in pregnant mothers yet the patient is advised to consult a doctor before taking this drug during pregnancy.
Breast Feeding
Caution
No harmful interaction has been reported in breastfeeding mothers yet the patient is advised to consult a doctor before taking this drug.
Driving
Caution
Caution is to be taken. If a patient feels dizzy while taking Onglyza 2.5 mg Tablet 14's, do not drive or use any tools or machines. Hypoglycaemia may affect your ability to drive and use machines or work with a safe foothold and there is a risk of hypoglycaemia after taking this medicine in combination with other medicines known to cause hypoglycaemia such as insulin and sulphonylureas.
Liver
Caution
Caution is to be taken in liver patients. Patients with severe liver problems are not advised to take this drug without doctor's consultation.
Kidney
Caution
Caution is to be taken in kidney patients. Patients with reduced kidney function are advised to consult with a doctor before taking Onglyza 2.5 mg Tablet 14's as the doctor may decrease the dose as per his own judgment.
Children
Caution
Onglyza 2.5 mg Tablet 14's is not recommended for children and adolescents under 18 years. It is not known if this medicine is safe and effective when used in children and adolescents under 18 years of age,thus doctors consultation is required.
About Onglyza 2.5 mg Tablet 14's
Onglyza 2.5 mg Tablet 14's contains saxagliptin which belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors used in the treatment of type 2 diabetes in adults. Onglyza 2.5 mg Tablet 14's is prescribed for the condition of type 2 diabetes when diet and exercise alone cannot control their blood sugar levels. It is the first-line therapy for patients with type 2 diabetes that restores the body's response to insulin. Insulin is the hormone that controls sugar levels in your blood. People with type 2 diabetes either do not produce enough insulin or the insulin produced is unable to perform its function in the body (insulin resistance). Middle-aged or older individuals are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes.
Onglyza 2.5 mg Tablet 14's work by blocking the action of DPP-4 (an enzyme which destroys hormone ‘Incretin’). The enzyme ‘Incretins’ help to produce more insulin only when required and reduce blood sugar level produced by the liver when not needed. Onglyza 2.5 mg Tablet 14's should not be used in patients with type 1 diabetes and for the treatment of diabetic ketoacidosis.
Onglyza 2.5 mg Tablet 14's should be taken with food or empty stomach. However, it should be taken at the same time of the day each time for best results. For better advice, your doctor will decide, what dose should be taken and it can change timely depending upon your condition. The most common side effect of Onglyza 2.5 mg Tablet 14's are hypoglycemia (low blood glucose levels), upper respiratory tract infection, nasopharyngitis (infection of nose and throat with common cold) and headache.
Prolonged intake of Onglyza 2.5 mg Tablet 14's may cause acute pancreatitis (swollen pancreas), and critical kidney problem. Increased risk of hypoglycemia (low blood sugar level) can occur when Onglyza 2.5 mg Tablet 14's is added to other anti-diabetic agents or insulin therapy. In this case, your doctor may adjust the dose of Onglyza 2.5 mg Tablet 14's. Severe allergic reactions might occur in some patients taking Onglyza 2.5 mg Tablet 14's like anaphylaxis, angioedema (swelling under the skin), and exfoliative skin conditions including Stevens-Johnson syndrome. Safety and efficacy of Onglyza 2.5 mg Tablet 14's in children under 18 years have not been established, so it should not be given to them. Patients taking digoxin (a heart medicine) with Onglyza 2.5 mg Tablet 14's should be closely monitored as severe drug interaction has been observed.
Uses of Onglyza 2.5 mg Tablet 14's
Medicinal Benefits
Onglyza 2.5 mg Tablet 14's work by blocking the action of DPP-4 (an enzyme which destroys hormone ‘Incretin’). The enzyme ‘Incretins’ help to produce more insulin only when required and reduce blood sugar level produced by the liver when not needed. Thus, Onglyza 2.5 mg Tablet 14's plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer and delayed wound healing.
Directions for Use
Side Effects of Onglyza 2.5 mg Tablet 14's
Drug Warnings
Increased risk of hypoglycemia (low blood sugar level) can occur when Onglyza 2.5 mg Tablet 14's is added to other anti-diabetic agents or insulin therapy. In this case, your doctor may adjust the dose of Onglyza 2.5 mg Tablet 14's. Prolonged intake of Onglyza 2.5 mg Tablet 14's may cause acute pancreatitis (swollen pancreas), and critical kidney problem. Severe allergic reactions might occur in some patients taking Onglyza 2.5 mg Tablet 14's like anaphylaxis, angioedema (swelling under the skin), and exfoliative skin conditions including Stevens-Johnson syndrome. Safety and efficacy of Onglyza 2.5 mg Tablet 14's in children under 18 years have not been established, so it should not be given to them. Patients taking digoxin (a heart medicine) with Onglyza 2.5 mg Tablet 14's should be closely monitored as severe drug interaction has been observed.
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