What is the best body site to inject Nobeglar-Uno 100IU Prefilled Pen 3 ml?

Nobeglar-Uno 100IU Prefilled Pen 3 ml should not be given into the veins or intravenously (IV) route. It should be only administered in the subcutaneous region below the skin. Abdomen regions (stomach) is the best site for the injecting Nobeglar-Uno 100IU Prefilled Pen 3 ml. However, you can also inject Nobeglar-Uno 100IU Prefilled Pen 3 ml in the upper arm, or thigh region.

Is Nobeglar-Uno 100IU Prefilled Pen 3 ml safe to use in every diabetic patient?

Nobeglar-Uno 100IU Prefilled Pen 3 ml can be given to treat both the condition of type 1 and type 2 diabetes mellitus. However, your doctor will decide whether Nobeglar-Uno 100IU Prefilled Pen 3 ml can be given to you or not depending on your present condition. Nobeglar-Uno 100IU Prefilled Pen 3 ml should be avoided in patients who are allergic to Nobeglar-Uno 100IU Prefilled Pen 3 ml or other forms of insulin. It should be avoided in patients suffering from low potassium level (hypokalemia), moderate to severe kidney disease or liver disease. Inform the doctor if you are pregnant or breastfeeding.

What does Nobeglar-Uno 100IU Prefilled Pen 3 ml contains?

The active substance is insulin glargine. Each ml of the solution contains 100 units of insulin glargine (equivalent to 3.64 mg).

How to store Nobeglar-Uno 100IU Prefilled Pen 3 ml?

Nobeglar-Uno 100IU Prefilled Pen 3 ml is a cold chain medicine which has to be stored 2-8 degree Celsius only else its efficiency of reducing blood glucose level declines. Do not keep inside the freezer.

Does Type-2 Diabetes occur in children?

Type-2 diabetes generally does not affect healthy children and teens, but it may affect children who are obese, which is also known as Childhood Obesity.

Can Nobeglar-Uno 100IU Prefilled Pen 3 ml be taken with other anti-diabetic medications?

Nobeglar-Uno 100IU Prefilled Pen 3 ml is generally safe to take for a long time. In fact, it works best if you take it for many months or even years.

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Nobeglar-Uno 100IU Prefilled Pen 3 ml

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Nobeglar-Uno 100IU Prefilled Pen 3 ml

About Nobeglar-Uno 100IU Prefilled Pen 3 ml

Nobeglar-Uno 100IU Prefilled Pen 3 ml is a long-acting insulin that contains insulin glargine. This is a modified insulin, very similar to human insulin. Human insulin is the name which describes synthetic (human-made) insulin, which is laboratory grown to mimic the insulin in humans. Nobeglar-Uno 100IU Prefilled Pen 3 ml is used to treat diabetes mellitus in adults, adolescents and children aged two years and above. Diabetes mellitus is a disease where your body does not produce enough insulin to control the level of blood sugar. Nobeglar-Uno 100IU Prefilled Pen 3 ml has a long and steady blood-sugar-lowering action. Long-acting insulin takes about 2 hours to start acting and is designed to work uniformly so that there is no peak activity as such. The duration of long-acting insulin is up to 24 hours. Treatment with Nobeglar-Uno 100IU Prefilled Pen 3 ml helps to prevent complications from your diabetes. Do not use Nobeglar-Uno 100IU Prefilled Pen 3 ml to treat diabetic ketoacidosis (too much acid in the blood).

Nobeglar-Uno 100IU Prefilled Pen 3 ml is a long-acting insulin that works by ensuring consistent sugar control. Hence, it helps lower blood sugar levels throughout the day. Based on your lifestyle, the results of your blood sugar (glucose) tests, and your previous insulin usage. Your doctor will advise you how much Nobeglar-Uno 100IU Prefilled Pen 3 ml per day you will need and when you need to take it.

Sometimes, you may experience injection site reactions such as lumps under the skin. The injection site should be rotated to prevent skin changes such as lumps under the skin. You may also experience symptoms of hypoglycaemia (low blood sugar) such as sweating, clammy skin, anxiety, fast heartbeat. Most of these side effects of Nobeglar-Uno 100IU Prefilled Pen 3 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking Nobeglar-Uno 100IU Prefilled Pen 3 ml of your own. Let your doctor know about this, as it may cause withdrawal symptoms. Do not take Nobeglar-Uno 100IU Prefilled Pen 3 ml if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs. Along with Nobeglar-Uno 100IU Prefilled Pen 3 ml, you should take a healthy diet, exercise regularly, and maintain weight as your doctor advises. Nobeglar-Uno 100IU Prefilled Pen 3 ml is a cold chain medicine, so it must be stored in the refrigerator between 2-8 degrees Celsius; otherwise, its efficiency might get lost. Do not store it in the freezer of the fridge.

Uses of Nobeglar-Uno 100IU Prefilled Pen 3 ml

Diabetes (Type 1 diabetes mellitus, Type 2 diabetes mellitus)

Medicinal Benefits

Nobeglar-Uno 100IU Prefilled Pen 3 ml has a long and steady blood-sugar-lowering action. Long-acting insulin takes about 2 hours to start acting and is designed to work uniformly so that there is no peak activity as such. The duration of long-acting insulin is up to 24 hours. This insulin causes body tissues to absorb glucose from the blood and decreases glucose production by the liver. Nobeglar-Uno 100IU Prefilled Pen 3 ml helps in improving the glycaemic control, which in turn reduces the risk of progression of complications of diabetes like damage to the retina (retinopathy), impairment of kidney (nephropathy), injury of nerve cells (neuropathy), delayed wound healing, diabetic foot ulcer and others. Besides this, Nobeglar-Uno 100IU Prefilled Pen 3 ml can be safely prescribed to pregnant and lactating mothers.

Directions for Use

Nobeglar-Uno 100IU Prefilled Pen 3 ml is injected under the skin (subcutaneously). Do NOT inject Nobeglar-Uno 100IU Prefilled Pen 3 ml in a vein. You need one injection of Nobeglar-Uno 100IU Prefilled Pen 3 ml every day, at the same time of the day. If you are not well trained to self-administer Nobeglar-Uno 100IU Prefilled Pen 3 ml, ask healthcare professional to administer it.Procedure for self-injecting insulin:•You should wash your hand first before injecting insulin.•Then roll the insulin bottle and wipe the bottle top.•Now pull the plunger of the syringe down to an appropriate number of units your doctor has prescribed.•Push the needle into the bottle and push the syringe plunger down.•Now once again pull the plunger down to an appropriate number of units as prescribed by the doctor.•Pick the injection site and wipe it with an alcohol swab. Now, pinch up the skin and push the needle into the skin and then push the plunger in.•The needle should be kept under the skin for at least 6 seconds to make sure the entire dose is injected.•After injecting the insulin pull out the needle and dispose of the syringe safely. And then you can have a meal or snack.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Nobeglar-Uno 100IU Prefilled Pen 3 ml

Low blood sugar or hypoglycaemia
Cold sweat
Cool pale skin
Nervousness
Anxious feeling
Unusual tiredness or weakness
Confusion
Difficulty in concentration
Drowsiness
Excessive hunger
Temporary vision changes
Headache
Nausea
Increased pulse or heartbeat (palpitation)

Drug Warnings

Nobeglar-Uno 100IU Prefilled Pen 3 ml is for subcutaneous (under the skin) use only and should never be administered intravenously (IV) or in the veins. If you are changing the brand of insulin or if you need to inject your insulin by another method, it should be done under strict medical supervision. Cases of heart failure were reported when pioglitazone was used with insulin, especially in patients at high risk of cardiac heart failure. The first symptoms of hyperglycaemia (high blood sugar level) may include symptoms like excessive thirst, dry mouth, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, loss of appetite and acetone odour of the breath. You should closely monitor these symptoms. Symptoms like heart failure, weight gain and oedema (fluid deposition in tissue) should not be overruled. It is advisable not to consume alcohol as it may increase or decrease your blood glucose level. Care should be taken while travelling across more than two time zones. Your doctor may adjust your insulin schedule. Nobeglar-Uno 100IU Prefilled Pen 3 ml may decrease the potassium level, leading to a state of hypokalaemia that, if left untreated, may lead to respiratory paralysis, irregular heartbeat rhythm, coma and even death. Do not take Nobeglar-Uno 100IU Prefilled Pen 3 ml if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs.

Drug Interactions

Drug-Drug Interactions: Nobeglar-Uno 100IU Prefilled Pen 3 ml may have an interaction with all other antidiabetic pills (sitagliptin), blood sugar enhancers (diazoxide), blood pressure-lowering pills (metoprolol, clonidine), antidepressants (lithium, fluoxetine), pain killers (aspirin, pentoxifylline, propoxyphene), anti TB drug (isoniazid), growth hormone (somatropin), thyroid hormone-related drugs (levothyroxine), antipsychotic medicines (phenothiazine, clozapine, olanzapine), anti-cholesterol drugs (fenofibrate), anti-asthmatic (epinephrine, salbutamol, terbutaline), female hormones like oestrogens and progestogens.

Drug-Food Interactions: Nobeglar-Uno 100IU Prefilled Pen 3 ml may interact with an ayurvedic, homoeopathy, Unani, herbal supplements or OTC items. Tell your doctor if you are using these products. Avoid drinking alcoholic beverages with Nobeglar-Uno 100IU Prefilled Pen 3 ml as it may raise or lower your blood sugar level.

Drug-Disease Interactions: Nobeglar-Uno 100IU Prefilled Pen 3 ml should not be given to patients with kidney disease, liver disease, low blood sugar/glucose level (hypoglycaemia), and low potassium level (hypokalaemia).

Drug-Drug Interactions Checker List

ASPIRIN
SITAGLIPTIN
PREGABALIN
METOPROLOL
LEVOTHYROXINE SODIUM
CLONIDINE
LITHIUM
FLUOXETINE
RIFAMPICIN+ISONIAZID
CLOZAPINE
OLANZAPINE
FENOFIBRATE
EPINEPHRINE
SALBUTAMOL
ESTROGEN
PROGESTERONE

Habit Forming

Diet & Lifestyle Advise

Exercise may lower your body’s need for insulin during and sometimes after physical activity.
Exercise may also speed up the effect of an insulin dose, especially if the activity involves the area of the injection site (for example, the leg should not be used for injection just before running).
Discuss with your doctor how to adjust your insulin regimen to accommodate exercise.
Avoid eating sugar food and prefer food cooked food low in calories.
When travelling across more than two time zones, you should talk to your doctor concerning adjustments in your insulin schedule.

Special Advise

Change (rotate) your injection sites within the area you chose with each dose to reduce your risk of getting lipodystrophy (pitted or thickened skin) and localized cutaneous amyloidosis (skin with lumps) at the injection sites. Do not use the same spot for each injection or injection where the skin is pitted, thickened, lumpy, tender, bruised, scaly, hard, scarred or damaged.

Disease/Condition Glossary

Diabetes: Diabetes is a chronic or lifelong disease that prevents the body from utilizing insulin properly. Insulin is the hormone that controls sugar levels in the blood. Diabetes is a condition in which blood glucose levels are above normal. It is of two types, namely: type-1 and type-2 diabetes. Type-1 diabetes is a condition in which the pancreas produces little or no insulin. Type-2 diabetes affects the way body processes the sugar. Symptoms of diabetes include lack of energy, tiredness, frequent urination, excess thirst, dry mouth, blurry vision, constant hunger, weight loss, and itchy skin.

Reference

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