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  1. Home
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  3. Nivmet Injection

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Composition :

METRONIDAZOLE-0.5GM

Manufacturer/Marketer :

Nivy Remedies Pvt Ltd

Consume Type :

Parenteral

Return Policy :

Not Returnable

Therapeutic Class

[ANTIBIOTICS]

Country of origin

India
Other Info - NI65537

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:46 AM IST

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FAQs

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Safe if prescribed

You are recommended not to consume alcohol along with Nivmet Injection to avoid unpleasant side effects such as stomach pain, nausea, vomiting, flushing, and headache.

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Pregnancy

Consult your doctor

Please consult your doctor. Nivmet Injection should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Consult your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Nivmet Injection.

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Driving

Safe if prescribed

Nivmet Injection may cause dizziness and drowsiness; thus, avoid operating machinery or driving vehicles unless you are alert.

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Liver

Consult your doctor

Nivmet Injection to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending upon your liver condition.

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Kidney

Consult your doctor

Nivmet Injection to be taken with extreme caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending upon your kidney condition.

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Children

Safe if prescribed

Limited information about the use of Nivmet Injection in paediatric patients. Please seek medical advice. Your doctor will weigh the benefits and risks before prescribing this medicine to your child.

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Reference

  1. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=d46870f5-e2b1-46bd-8413-4a0a8bcf3175&type=display
  2. https://www.medicines.org.uk/emc/files/pil.13293.pdf
  3. https://www.medicines.org.uk/emc/product/1842/smpc#gref
  4. https://www.nhs.uk/medicines/metronidazole/about-metronidazole/
  5. https://www.drugs.com/drug-interactions/metronidazole-index.html?filter=3

About Nivmet Injection

Nivmet Injection belongs to a group of medicines known as anti-bacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, gynaecological infections, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves). 

Nivmet Injection contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causes helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thereby Nivmet Injection treats bacterial infections.

Nivmet Injection will be administered by a healthcare professional; do not self-administer. Some common side effects of Nivmet Injection are nausea, vomiting, diarrhoea, constipation, and injection site reaction. These side effects are temporary and may get resolved after some time. However, if any of the side effects persist or worsen, contact the doctor.

Let your doctor know if you are allergic to metronidazole. Consult your doctor if you are pregnant, planning to get pregnant, or if you are breastfeeding. Do not operate heavy machinery or drive after taking Nivmet Injection as it may cause dizziness and drowsiness. Avoid consumption of alcohol while on treatment with Nivmet Injection as it may cause unpleasant side effects.

Uses of Nivmet Injection

Bacterial infections

Medicinal Benefits Mweb

Key Benefits

Nivmet Injection belongs to a group of medicines known as anti-bacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, gynecologic, respiratory infections, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves). Nivmet Injection contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causes helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thereby Nivmet Injection treats bacterial infections.

Directions for Use

Nivmet Injection will be administered by a qualified healthcare professional. Kindly do not self-administer.

Side Effects of Nivmet Injection

  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Injection site reactions

Drug Warnings

Do not take Nivmet Injection if you are allergic to any of the components. Consult your doctor if you are pregnant, plan to get pregnant or if you are breastfeeding. Do not operate heavy machinery or drive after taking Nivmet Injection as it may cause dizziness and drowsiness. Inform your doctor if you have bone marrow depression/low blood count, kidney impairment, CNS disorder, liver or heart problems, peripheral neuropathy, epilepsy, Crohn's disease (a condition in which the body attacks the lining of the digestive tract), yeast infection, oedema (swelling), or blood disorders.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Nivmet Injection:
Co-administration of Amprenavir with Nivmet Injection can increase the risk or severity of side effects.

How to manage the interaction:
Taking Nivmet Injection with Amprenavir is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience throbbing in the head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nivmet Injection:
Drinking alcohol while taking Nivmet Injection can increase the risk or severity of side effects.

How to manage the interaction:
Taking Nivmet Injection with Ethanol is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nivmet Injection:
Coadministration of Disulfiram with Nivmet Injection can increase the risk of side effects.

How to manage the interaction:
Taking Nivmet Injection and Disulfiram together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, confusion, weakness, shortness of breath, or palpitations, contact your doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Nivmet Injection:
Coadministration of Nivmet Injection with warfarin can increase the risk of bleeding.

How to manage the interaction:
There is a possible interaction between Nivmet Injection and warfarin, but they can be taken together if a doctor has prescribed them. Consult a doctor if experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not stop using any medications without talking to a doctor.
How does the drug interact with Nivmet Injection:
Coadministration of Busulfan and Nivmet Injection may increase the risk of side effects.

How to manage the interaction:
Taking Nivmet Injection and Busulfan together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience unusual bruising or bleeding, fever, diarrhea, sore throat, muscle aches, shortness of breath, or burning during urination, contact a doctor immediately. Do not discontinue the medication without a doctor's advice.
How does the drug interact with Nivmet Injection:
Coadministration of Nivmet Injection with mebendazole may increase the risk or severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Nivmet Injection and mebendazole, they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms like fever, body ache, painful red rash, cough, peeling of the skin, or Drooling, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Nivmet Injection:
Co-administration of Fluconazole together with Nivmet Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
-Taking Nivmet Injection with Fluconazole together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • AMPRENAVIR
  • ANISINDIONE
  • DICUMAROL
  • WARFARIN
  • BCG VACCINE
  • CHOLERA VACCINE LIVE
  • TYPHOID VACCINE LIVE
  • BUSULFAN
  • DISULFIRAM

Habit Forming

No

Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Nivmet Injection to restore healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Whole grains like whole-grain bread, and brown rice, should be included in the diet.
  • Avoid intake of alcoholic beverages with Nivmet Injection as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Nivmet Injection in fighting off infections.

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